2IK7A

Yeast inorganic pyrophosphatase variant d120n with magnesium and phosphate
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
281
structure length
277
Chain Sequence
TYTTRQIGAKNTLEYKVYIEKDGKPVSAFHDIPLYADKENNIFNMVVEIPRWTNAKLEITKEETLNPIIQDTKKGKLRFVRNCFPHHGYIHNYGAFPQTWEDPNVSHPETKAVGDNDPINVLEIGETIAYTGQVKQVKALGIMALLDEGETDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAFSGEAKNKKYALDIIKETHDSWKQLIAGKSSDSKGIDLTNVTLPTYSKAASDAIPPASKADAPIDKSIDKWFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Saccharomyces cerevisiae
molecule keywords Inorganic pyrophosphatase
total genus 80
structure length 277
sequence length 281
chains with identical sequence B
ec nomenclature ec 3.6.1.1: Inorganic diphosphatase.
pdb deposition date 2006-10-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00719 Pyrophosphatase Inorganic pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.80.10 Alpha Beta Alpha-Beta Complex Inorganic Pyrophosphatase Inorganic pyrophosphatase 2ik7A00
117EA 4XELA 1I40A 3EJ2A 1TWLA 2AU8A 1INOA 4Z70A 2IK1A 2BQYA 3FQ3A 1HUKA 4Z72A 2UXSA 3Q4WA 3EMJA 3EIYA 2PRDA 1MJXA 2IHPA 2IK4A 1YGZA 3R5UA 1MJWA 3LO0A 4QMBA 2AU6A 2IK2A 2AU7A 1OBWA 4Z74A 3I4QA 1IPWA 5KDFA 3EIZA 2IK9A 3Q46A 1WGIA 3D63A 1MJYA 1WCFA 3SW5A 3I98A 1M38A 2IK0A 3D53A 3R5VA 1I6TA 3Q3LA 1WGJA 3EJ0A 1FAJA 2AUUA 1IGPA 1UDEA 2IK6A 4Z71A 3R6EA 3Q5VA 5KDEA 4ECPA 1PYPA 5TEAA 1MJZA 4UM4A 1QEZA 1SXVA 2AU9A 1YPPA 8PRKA 3TR4A 3GVFA 2EIPA 2IK7A 1JFDA 3LD3A 4Z73A 5H4FA 1E6AA 1HUJA 4QLZA 2BQXA 1E9GA 4LUGA
chains in the Genus database with same CATH superfamily
117EA 4XELA 1I40A 3EJ2A 1TWLA 2AU8A 1INOA 4Z70A 2IK1A 2BQYA 3FQ3A 1HUKA 4Z72A 2UXSA 3Q4WA 3EMJA 3EIYA 2PRDA 1MJXA 2IHPA 2IK4A 1YGZA 3R5UA 1MJWA 3LO0A 4QMBA 2AU6A 2IK2A 2AU7A 1OBWA 4Z74A 3I4QA 1IPWA 5KDFA 3EIZA 2IK9A 3Q46A 1WGIA 3D63A 1MJYA 1WCFA 3SW5A 3I98A 1M38A 2IK0A 3D53A 3R5VA 1I6TA 3Q3LA 1WGJA 3EJ0A 1FAJA 2AUUA 1IGPA 1UDEA 2IK6A 4Z71A 3R6EA 3Q5VA 5KDEA 4ECPA 1PYPA 5TEAA 1MJZA 4UM4A 1QEZA 1SXVA 2AU9A 1YPPA 8PRKA 3TR4A 3GVFA 2EIPA 2IK7A 1JFDA 3LD3A 4Z73A 5H4FA 1E6AA 1HUJA 4QLZA 2BQXA 1E9GA 4LUGA
chains in the Genus database with same CATH topology
117EA 4XELA 1I40A 3EJ2A 1TWLA 2AU8A 1INOA 4Z70A 2IK1A 2BQYA 3FQ3A 1HUKA 4Z72A 2UXSA 3Q4WA 3EMJA 3EIYA 2PRDA 1MJXA 2IHPA 2IK4A 1YGZA 3R5UA 1MJWA 3LO0A 4QMBA 2AU6A 2IK2A 2AU7A 1OBWA 4Z74A 3I4QA 1IPWA 5KDFA 3EIZA 2IK9A 3Q46A 1WGIA 3D63A 1MJYA 1WCFA 3SW5A 3I98A 1M38A 2IK0A 3D53A 3R5VA 1I6TA 3Q3LA 1WGJA 3EJ0A 1FAJA 2AUUA 1IGPA 1UDEA 2IK6A 4Z71A 3R6EA 3Q5VA 5KDEA 4ECPA 1PYPA 5TEAA 1MJZA 4UM4A 1QEZA 1SXVA 2AU9A 1YPPA 8PRKA 3TR4A 3GVFA 2EIPA 2IK7A 1JFDA 3LD3A 4Z73A 5H4FA 1E6AA 1HUJA 4QLZA 2BQXA 1E9GA 4LUGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 117E A;  4XEL A;  1I40 A;  3EJ2 A;  1TWL A;  2AU8 A;  1INO A;  4Z70 A;  2IK1 A;  2BQY A;  3FQ3 A;  1HUK A;  4Z72 A;  2UXS A;  3Q4W A;  3EMJ A;  3EIY A;  2PRD A;  1MJX A;  2IHP A;  2IK4 A;  1YGZ A;  3R5U A;  1MJW A;  3LO0 A;  4QMB A;  2AU6 A;  2IK2 A;  2AU7 A;  1OBW A;  4Z74 A;  3I4Q A;  1IPW A;  5KDF A;  3EIZ A;  2IK9 A;  3Q46 A;  1WGI A;  3D63 A;  1MJY A;  1WCF A;  3SW5 A;  3I98 A;  1M38 A;  2IK0 A;  3D53 A;  3R5V A;  1I6T A;  3Q3L A;  1WGJ A;  3EJ0 A;  1FAJ A;  2AUU A;  1IGP A;  1UDE A;  2IK6 A;  4Z71 A;  3R6E A;  3Q5V A;  5KDE A;  4ECP A;  1PYP A;  5TEA A;  1MJZ A;  4UM4 A;  1QEZ A;  1SXV A;  2AU9 A;  1YPP A;  8PRK A;  3TR4 A;  3GVF A;  2EIP A;  2IK7 A;  1JFD A;  3LD3 A;  4Z73 A;  5H4F A;  1E6A A;  1HUJ A;  4QLZ A;  2BQX A;  1E9G A;  4LUG A; 
#chains in the Genus database with same CATH topology
 117E A;  4XEL A;  1I40 A;  3EJ2 A;  1TWL A;  2AU8 A;  1INO A;  4Z70 A;  2IK1 A;  2BQY A;  3FQ3 A;  1HUK A;  4Z72 A;  2UXS A;  3Q4W A;  3EMJ A;  3EIY A;  2PRD A;  1MJX A;  2IHP A;  2IK4 A;  1YGZ A;  3R5U A;  1MJW A;  3LO0 A;  4QMB A;  2AU6 A;  2IK2 A;  2AU7 A;  1OBW A;  4Z74 A;  3I4Q A;  1IPW A;  5KDF A;  3EIZ A;  2IK9 A;  3Q46 A;  1WGI A;  3D63 A;  1MJY A;  1WCF A;  3SW5 A;  3I98 A;  1M38 A;  2IK0 A;  3D53 A;  3R5V A;  1I6T A;  3Q3L A;  1WGJ A;  3EJ0 A;  1FAJ A;  2AUU A;  1IGP A;  1UDE A;  2IK6 A;  4Z71 A;  3R6E A;  3Q5V A;  5KDE A;  4ECP A;  1PYP A;  5TEA A;  1MJZ A;  4UM4 A;  1QEZ A;  1SXV A;  2AU9 A;  1YPP A;  8PRK A;  3TR4 A;  3GVF A;  2EIP A;  2IK7 A;  1JFD A;  3LD3 A;  4Z73 A;  5H4F A;  1E6A A;  1HUJ A;  4QLZ A;  2BQX A;  1E9G A;  4LUG A; 
#chains in the Genus database with same CATH homology
 117E A;  4XEL A;  1I40 A;  3EJ2 A;  1TWL A;  2AU8 A;  1INO A;  4Z70 A;  2IK1 A;  2BQY A;  3FQ3 A;  1HUK A;  4Z72 A;  2UXS A;  3Q4W A;  3EMJ A;  3EIY A;  2PRD A;  1MJX A;  2IHP A;  2IK4 A;  1YGZ A;  3R5U A;  1MJW A;  3LO0 A;  4QMB A;  2AU6 A;  2IK2 A;  2AU7 A;  1OBW A;  4Z74 A;  3I4Q A;  1IPW A;  5KDF A;  3EIZ A;  2IK9 A;  3Q46 A;  1WGI A;  3D63 A;  1MJY A;  1WCF A;  3SW5 A;  3I98 A;  1M38 A;  2IK0 A;  3D53 A;  3R5V A;  1I6T A;  3Q3L A;  1WGJ A;  3EJ0 A;  1FAJ A;  2AUU A;  1IGP A;  1UDE A;  2IK6 A;  4Z71 A;  3R6E A;  3Q5V A;  5KDE A;  4ECP A;  1PYP A;  5TEA A;  1MJZ A;  4UM4 A;  1QEZ A;  1SXV A;  2AU9 A;  1YPP A;  8PRK A;  3TR4 A;  3GVF A;  2EIP A;  2IK7 A;  1JFD A;  3LD3 A;  4Z73 A;  5H4F A;  1E6A A;  1HUJ A;  4QLZ A;  2BQX A;  1E9G A;  4LUG A; 
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