2IVHA

Crystal structure of the nuclease domain of cole7 (h545q mutant) in complex with an 18-bp duplex dna
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
128
structure length
124
Chain Sequence
KPGKATGKGKPVNNKWLNNAGKDLGSPVPDRIANKLRDKEFKSFDDFRKKFWEEVSKDPELSKQFSRNNNDRMKVGKAPKTRTQDVSGKRTSFELHQEKPISVYDMDNISVVTPKRHIDIHRGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Sequence-Dependent DNA Cleavage by Nonspecific Endonucleases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords COLCIN-E7
total genus 42
structure length 124
sequence length 128
ec nomenclature ec 3.1.-.-:
pdb deposition date 2006-06-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.540.10 Alpha Beta Alpha-Beta Complex Colicin E7 immunity protein; Chain B, fragment: Endonuclease domain Colicin/pyocin, DNase domain 2ivhA00
3U43B 4UHQA 1BXIB 2VLPB 3GJNB 1PT3A 1M08A 2ERHB 1EMVB 1V13A 2JBGB 2VLQB 2K5XB 2GZJB 2GYKB 1V15A 4QKOB 1FR2B 2GZFB 2WPTB 2JB0B 1ZNSA 1ZNVB 1MZ8B 2GZEB 2VLNB 2GZGB 2GZIB 4UHPA 7CEIB 2VLOB 3GKLA 1FSJB 1UJZB 2IVHA 3ZFKA 3FBDA 2JAZB 1V14A
chains in the Genus database with same CATH superfamily
3U43B 4UHQA 1BXIB 2VLPB 3GJNB 1PT3A 1M08A 2ERHB 1EMVB 1V13A 2JBGB 2VLQB 2K5XB 2GZJB 2GYKB 1V15A 4QKOB 1FR2B 2GZFB 2WPTB 2JB0B 1ZNSA 1ZNVB 1MZ8B 2GZEB 2VLNB 2GZGB 2GZIB 4UHPA 7CEIB 2VLOB 3GKLA 1FSJB 1UJZB 2IVHA 3ZFKA 3FBDA 2JAZB 1V14A
chains in the Genus database with same CATH topology
3U43B 4UHQA 1BXIB 2VLPB 3GJNB 1PT3A 1M08A 2ERHB 1EMVB 1V13A 2JBGB 2VLQB 2K5XB 2GZJB 2GYKB 1V15A 4QKOB 1FR2B 2GZFB 2WPTB 2JB0B 1ZNSA 1ZNVB 1MZ8B 2GZEB 2VLNB 2GZGB 2GZIB 4UHPA 7CEIB 2VLOB 3GKLA 1FSJB 1UJZB 2IVHA 3ZFKA 3FBDA 2JAZB 1V14A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U43 B;  4UHQ A;  1BXI B;  2VLP B;  3GJN B;  1PT3 A;  1M08 A;  2ERH B;  1EMV B;  1V13 A;  2JBG B;  2VLQ B;  2K5X B;  2GZJ B;  2GYK B;  1V15 A;  4QKO B;  1FR2 B;  2GZF B;  2WPT B;  2JB0 B;  1ZNS A;  1ZNV B;  1MZ8 B;  2GZE B;  2VLN B;  2GZG B;  2GZI B;  4UHP A;  7CEI B;  2VLO B;  3GKL A;  1FSJ B;  1UJZ B;  2IVH A;  3ZFK A;  3FBD A;  2JAZ B;  1V14 A; 
#chains in the Genus database with same CATH topology
 3U43 B;  4UHQ A;  1BXI B;  2VLP B;  3GJN B;  1PT3 A;  1M08 A;  2ERH B;  1EMV B;  1V13 A;  2JBG B;  2VLQ B;  2K5X B;  2GZJ B;  2GYK B;  1V15 A;  4QKO B;  1FR2 B;  2GZF B;  2WPT B;  2JB0 B;  1ZNS A;  1ZNV B;  1MZ8 B;  2GZE B;  2VLN B;  2GZG B;  2GZI B;  4UHP A;  7CEI B;  2VLO B;  3GKL A;  1FSJ B;  1UJZ B;  2IVH A;  3ZFK A;  3FBD A;  2JAZ B;  1V14 A; 
#chains in the Genus database with same CATH homology
 3U43 B;  4UHQ A;  1BXI B;  2VLP B;  3GJN B;  1PT3 A;  1M08 A;  2ERH B;  1EMV B;  1V13 A;  2JBG B;  2VLQ B;  2K5X B;  2GZJ B;  2GYK B;  1V15 A;  4QKO B;  1FR2 B;  2GZF B;  2WPT B;  2JB0 B;  1ZNS A;  1ZNV B;  1MZ8 B;  2GZE B;  2VLN B;  2GZG B;  2GZI B;  4UHP A;  7CEI B;  2VLO B;  3GKL A;  1FSJ B;  1UJZ B;  2IVH A;  3ZFK A;  3FBD A;  2JAZ B;  1V14 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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