2J4HA

Crystal structure of a h121a escherichia coli dctp deaminase mutant enzyme
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
174
structure length
174
Chain Sequence
MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPADLVGWLDGRSSLARLGLMVAVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAVRPYNRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE
total genus 38
structure length 174
sequence length 174
chains with identical sequence B
ec nomenclature ec 3.5.4.13: dCTP deaminase.
pdb deposition date 2006-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 2j4hA01
1F7OA 3CA9A 3TPNA 3T60A 5CCTA 3ARAA 1XS6A 2D4MA 5ECTA 3TQ4A 3EHWA 3TS6A 1XS1A 2D4LA 1PKHA 1XS4A 3TP1A 2HR6A 3ZF5A 2BSYA 1DUDA 3F4FA 2WE2A 4A6AA 3T70A 1SJNA 2WE0A 1SIXA 2V9XA 5CCOA 3TRNA 1F7DA 2OKDA 2HXDA 3TQZA 2BT1A 3ZF2A 3C3IA 1F7QA 1F7RA 2XCDA 3T6YA 3TPWA 4WRKA 4AOZA 1DUNA 2XCEA 1RNJA 1DUTA 4OOQA 1F7KA 2WE1A 3T64A 3I93A 3H6DA 1RN8A 3TTAA 2J4HA 1SYLA 3MBQA 3C2TA 3GF0A 3TQ3A 2QLPA 1EUWA 4DHKA 2Y8CA 2D4NA 4GK6A 4OOPA 3KM3A 2R9QA 2YZJA 3LQWA 1DUCA 2HXBA 2XY3A 5F9KA 3LOJA 1F7PA 2J4QA 2PC5A 4APZ1 2OL1A 2XX6A 2Y1TA 3TQ5A 3TSLA 1OGHA 1SEHA 1SLHA 1SNFA 1SMCA 1DUPA 3TPYA 3HZAA 2HRMA 1F7NA 2BAZA 1MQ7A 1Q5UX 4AO5A 4AOOA 3ZF6A 2PY4A 3TRLA 3TPSA 5EDDA 3H6XA 2HQUA 2ZDCA 3ECYA 3SO2A 2OL0A 1Q5HA 4LHRA 4B0HA 3ZEZA 1VYQA 1PKKA 2QXXA 4GV8A 3MDXA 3HHQA 2OKEA 3ZF3A 1SM8A 3P48A 1PKJA 3ZF1A 2WE3A 4GCYA 4XJCA 3ZF0A 3ARNA 1EU5A 3ZF4A 2OKBA
chains in the Genus database with same CATH superfamily
1F7OA 3CA9A 3TPNA 3T60A 5CCTA 3ARAA 1XS6A 2D4MA 5ECTA 3TQ4A 3EHWA 3TS6A 1XS1A 2D4LA 1PKHA 1XS4A 3TP1A 2HR6A 3ZF5A 2BSYA 1DUDA 3F4FA 2WE2A 4A6AA 3T70A 1SJNA 2WE0A 1SIXA 2V9XA 5CCOA 3TRNA 1F7DA 2OKDA 2HXDA 3TQZA 2BT1A 3ZF2A 3C3IA 1F7QA 1F7RA 2XCDA 3T6YA 3TPWA 4WRKA 4AOZA 1DUNA 2XCEA 1RNJA 1DUTA 4OOQA 1F7KA 2WE1A 3T64A 3I93A 3H6DA 1RN8A 3TTAA 2J4HA 1SYLA 3MBQA 3C2TA 3GF0A 3TQ3A 2QLPA 1EUWA 4DHKA 2Y8CA 2D4NA 4GK6A 4OOPA 3KM3A 2R9QA 2YZJA 3LQWA 1DUCA 2HXBA 2XY3A 5F9KA 3LOJA 1F7PA 2J4QA 2PC5A 4APZ1 1TULA 2OL1A 2XX6A 2Y1TA 3TQ5A 3TSLA 1OGHA 1SEHA 1SLHA 1SNFA 1SMCA 1DUPA 3TPYA 3HZAA 2HRMA 1F7NA 2BAZA 1MQ7A 1Q5UX 4AO5A 4AOOA 3ZF6A 2PY4A 3TRLA 3TPSA 5EDDA 3H6XA 2HQUA 2ZDCA 3ECYA 3SO2A 2OL0A 1Q5HA 4LHRA 4B0HA 3ZEZA 1VYQA 1PKKA 2QXXA 4GV8A 3MDXA 3HHQA 2OKEA 3ZF3A 1SM8A 3P48A 1PKJA 3ZF1A 2WE3A 4GCYA 4XJCA 3ZF0A 3ARNA 1EU5A 3ZF4A 2OKBA
chains in the Genus database with same CATH topology
1F7OA 3CA9A 3TPNA 3T60A 5CCTA 3ARAA 1XS6A 2D4MA 5ECTA 3TQ4A 3EHWA 3TS6A 1XS1A 2D4LA 1PKHA 1XS4A 3TP1A 2HR6A 3ZF5A 2BSYA 1DUDA 3F4FA 2WE2A 4A6AA 3T70A 1SJNA 2WE0A 1SIXA 2V9XA 5CCOA 3TRNA 1F7DA 2OKDA 2HXDA 3TQZA 2BT1A 3ZF2A 3C3IA 1F7QA 1F7RA 2XCDA 3T6YA 3TPWA 4WRKA 4AOZA 1DUNA 2XCEA 1RNJA 1DUTA 4OOQA 1F7KA 2WE1A 3T64A 3I93A 3H6DA 1RN8A 3TTAA 2J4HA 1SYLA 3MBQA 3C2TA 3GF0A 3TQ3A 2QLPA 1EUWA 4DHKA 2Y8CA 2D4NA 4GK6A 4OOPA 3KM3A 2R9QA 2YZJA 3LQWA 1DUCA 2HXBA 2XY3A 5F9KA 3LOJA 1F7PA 2J4QA 2PC5A 4APZ1 2OL1A 2XX6A 2Y1TA 3TQ5A 3TSLA 1OGHA 1SEHA 1SLHA 1SNFA 1SMCA 1DUPA 3TPYA 3HZAA 2HRMA 1F7NA 2BAZA 1MQ7A 1Q5UX 4AO5A 4AOOA 3ZF6A 2PY4A 3TRLA 3TPSA 5EDDA 3H6XA 2HQUA 2ZDCA 3ECYA 3SO2A 2OL0A 1Q5HA 4LHRA 4B0HA 3ZEZA 1VYQA 1PKKA 2QXXA 4GV8A 3MDXA 3HHQA 2OKEA 3ZF3A 1SM8A 3P48A 1PKJA 3ZF1A 2WE3A 4GCYA 4XJCA 3ZF0A 3ARNA 1EU5A 3ZF4A 2OKBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F7O A;  3CA9 A;  3TPN A;  3T60 A;  5CCT A;  3ARA A;  1XS6 A;  2D4M A;  5ECT A;  3TQ4 A;  3EHW A;  3TS6 A;  1XS1 A;  2D4L A;  1PKH A;  1XS4 A;  3TP1 A;  2HR6 A;  3ZF5 A;  2BSY A;  1DUD A;  3F4F A;  2WE2 A;  4A6A A;  3T70 A;  1SJN A;  2WE0 A;  1SIX A;  2V9X A;  5CCO A;  3TRN A;  1F7D A;  2OKD A;  2HXD A;  3TQZ A;  2BT1 A;  3ZF2 A;  3C3I A;  1F7Q A;  1F7R A;  2XCD A;  3T6Y A;  3TPW A;  4WRK A;  4AOZ A;  1DUN A;  2XCE A;  1RNJ A;  1DUT A;  4OOQ A;  1F7K A;  2WE1 A;  3T64 A;  3I93 A;  3H6D A;  1RN8 A;  3TTA A;  2J4H A;  1SYL A;  3MBQ A;  3C2T A;  3GF0 A;  3TQ3 A;  2QLP A;  1EUW A;  4DHK A;  2Y8C A;  2D4N A;  4GK6 A;  4OOP A;  3KM3 A;  2R9Q A;  2YZJ A;  3LQW A;  1DUC A;  2HXB A;  2XY3 A;  5F9K A;  3LOJ A;  1F7P A;  2J4Q A;  2PC5 A;  4APZ 1;  2OL1 A;  2XX6 A;  2Y1T A;  3TQ5 A;  3TSL A;  1OGH A;  1SEH A;  1SLH A;  1SNF A;  1SMC A;  1DUP A;  3TPY A;  3HZA A;  2HRM A;  1F7N A;  2BAZ A;  1MQ7 A;  1Q5U X;  4AO5 A;  4AOO A;  3ZF6 A;  2PY4 A;  3TRL A;  3TPS A;  5EDD A;  3H6X A;  2HQU A;  2ZDC A;  3ECY A;  3SO2 A;  2OL0 A;  1Q5H A;  4LHR A;  4B0H A;  3ZEZ A;  1VYQ A;  1PKK A;  2QXX A;  4GV8 A;  3MDX A;  3HHQ A;  2OKE A;  3ZF3 A;  1SM8 A;  3P48 A;  1PKJ A;  3ZF1 A;  2WE3 A;  4GCY A;  4XJC A;  3ZF0 A;  3ARN A;  1EU5 A;  3ZF4 A;  2OKB A; 
#chains in the Genus database with same CATH topology
 1F7O A;  3CA9 A;  3TPN A;  3T60 A;  5CCT A;  3ARA A;  1XS6 A;  2D4M A;  5ECT A;  3TQ4 A;  3EHW A;  3TS6 A;  1XS1 A;  2D4L A;  1PKH A;  1XS4 A;  3TP1 A;  2HR6 A;  3ZF5 A;  2BSY A;  1DUD A;  3F4F A;  2WE2 A;  4A6A A;  3T70 A;  1SJN A;  2WE0 A;  1SIX A;  2V9X A;  5CCO A;  3TRN A;  1F7D A;  2OKD A;  2HXD A;  3TQZ A;  2BT1 A;  3ZF2 A;  3C3I A;  1F7Q A;  1F7R A;  2XCD A;  3T6Y A;  3TPW A;  4WRK A;  4AOZ A;  1DUN A;  2XCE A;  1RNJ A;  1DUT A;  4OOQ A;  1F7K A;  2WE1 A;  3T64 A;  3I93 A;  3H6D A;  1RN8 A;  3TTA A;  2J4H A;  1SYL A;  3MBQ A;  3C2T A;  3GF0 A;  3TQ3 A;  2QLP A;  1EUW A;  4DHK A;  2Y8C A;  2D4N A;  4GK6 A;  4OOP A;  3KM3 A;  2R9Q A;  2YZJ A;  3LQW A;  1DUC A;  2HXB A;  2XY3 A;  5F9K A;  3LOJ A;  1F7P A;  2J4Q A;  2PC5 A;  4APZ 1;  1TUL A;  2OL1 A;  2XX6 A;  2Y1T A;  3TQ5 A;  3TSL A;  1OGH A;  1SEH A;  1SLH A;  1SNF A;  1SMC A;  1DUP A;  3TPY A;  3HZA A;  2HRM A;  1F7N A;  2BAZ A;  1MQ7 A;  1Q5U X;  4AO5 A;  4AOO A;  3ZF6 A;  2PY4 A;  3TRL A;  3TPS A;  5EDD A;  3H6X A;  2HQU A;  2ZDC A;  3ECY A;  3SO2 A;  2OL0 A;  1Q5H A;  4LHR A;  4B0H A;  3ZEZ A;  1VYQ A;  1PKK A;  2QXX A;  4GV8 A;  3MDX A;  3HHQ A;  2OKE A;  3ZF3 A;  1SM8 A;  3P48 A;  1PKJ A;  3ZF1 A;  2WE3 A;  4GCY A;  4XJC A;  3ZF0 A;  3ARN A;  1EU5 A;  3ZF4 A;  2OKB A; 
#chains in the Genus database with same CATH homology
 1F7O A;  3CA9 A;  3TPN A;  3T60 A;  5CCT A;  3ARA A;  1XS6 A;  2D4M A;  5ECT A;  3TQ4 A;  3EHW A;  3TS6 A;  1XS1 A;  2D4L A;  1PKH A;  1XS4 A;  3TP1 A;  2HR6 A;  3ZF5 A;  2BSY A;  1DUD A;  3F4F A;  2WE2 A;  4A6A A;  3T70 A;  1SJN A;  2WE0 A;  1SIX A;  2V9X A;  5CCO A;  3TRN A;  1F7D A;  2OKD A;  2HXD A;  3TQZ A;  2BT1 A;  3ZF2 A;  3C3I A;  1F7Q A;  1F7R A;  2XCD A;  3T6Y A;  3TPW A;  4WRK A;  4AOZ A;  1DUN A;  2XCE A;  1RNJ A;  1DUT A;  4OOQ A;  1F7K A;  2WE1 A;  3T64 A;  3I93 A;  3H6D A;  1RN8 A;  3TTA A;  2J4H A;  1SYL A;  3MBQ A;  3C2T A;  3GF0 A;  3TQ3 A;  2QLP A;  1EUW A;  4DHK A;  2Y8C A;  2D4N A;  4GK6 A;  4OOP A;  3KM3 A;  2R9Q A;  2YZJ A;  3LQW A;  1DUC A;  2HXB A;  2XY3 A;  5F9K A;  3LOJ A;  1F7P A;  2J4Q A;  2PC5 A;  4APZ 1;  2OL1 A;  2XX6 A;  2Y1T A;  3TQ5 A;  3TSL A;  1OGH A;  1SEH A;  1SLH A;  1SNF A;  1SMC A;  1DUP A;  3TPY A;  3HZA A;  2HRM A;  1F7N A;  2BAZ A;  1MQ7 A;  1Q5U X;  4AO5 A;  4AOO A;  3ZF6 A;  2PY4 A;  3TRL A;  3TPS A;  5EDD A;  3H6X A;  2HQU A;  2ZDC A;  3ECY A;  3SO2 A;  2OL0 A;  1Q5H A;  4LHR A;  4B0H A;  3ZEZ A;  1VYQ A;  1PKK A;  2QXX A;  4GV8 A;  3MDX A;  3HHQ A;  2OKE A;  3ZF3 A;  1SM8 A;  3P48 A;  1PKJ A;  3ZF1 A;  2WE3 A;  4GCY A;  4XJC A;  3ZF0 A;  3ARN A;  1EU5 A;  3ZF4 A;  2OKB A; 
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similar chains in the Genus database (?% sequence similarity)
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