2LUTA

Nmr solution structure of midkine-a
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
125
structure length
125
Chain Sequence
GSKNKKEKNKGGKGGADCAEWLYGSCVANNGDCGQGMREGTCNEQTRKVKCRVPCNWKKEFGADCKYKFGNWGECDAATSTKSRTGTLQKALFNVECQQTVSVTKPCTTKVKNKPKGKKGKGKGN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Functional Characterization of Two Zebrafish Midkine Proteins Reveals Importance of the Conserved Hinge for Heparin Binding and Embryogenesis
rcsb
molecule tags Hormone
source organism Danio rerio
molecule keywords Midkine-related growth factor
total genus 4
structure length 125
sequence length 125
ec nomenclature
pdb deposition date 2012-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01091 PTN_MK_C PTN/MK heparin-binding protein family, C-terminal domain
A PF05196 PTN_MK_N PTN/MK heparin-binding protein family, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.60.10 Mainly Beta Single Sheet Heparin-binding Growth Factor, Midkine; Chain A Pleiotrophin/Midkine, N-terminal domain 2lutA01
2.30.90.10 Mainly Beta Roll Heparin-binding Growth Factor, Midkine; Chain A, C-terminal Domain; Heparin-binding Growth Factor, Midkine; Chain A- C-terminal Domain 2lutA02
2LUUA 1MKCA 1MKNA 2LUTA
chains in the Genus database with same CATH superfamily
2LUUA 1MKCA 1MKNA 2LUTA
chains in the Genus database with same CATH topology
2LUUA 1MKCA 1MKNA 2LUTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LUU A;  1MKC A;  1MKN A;  2LUT A; 
#chains in the Genus database with same CATH topology
 2LUU A;  1MKC A;  1MKN A;  2LUT A; 
#chains in the Genus database with same CATH homology
 2LUU A;  1MKC A;  1MKN A;  2LUT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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