2NY7G

Hiv-1 gp120 envelope glycoprotein complexed with the broadly neutralizing cd4-binding-site antibody b12
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
317
structure length
290
Chain Sequence
EVVLVNVTENFNWCKNDMVEQMHEDICSLWDQSLKPCVACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGPCTNVSTVQCTHGIRPVVSSQLLLNGSLAEEEVVIRSCNFTDNAKTIIVQLNTSVEINCTGAGHCNIARAKWNNTLKQIASKLREQFGNNKTIIFKQSSGGDPEIVTHWFNCGGEFFYCNSTQLFNSTWFNSTWSGSDTITLPCRIKQIINMWCKVGKMMYAPPISGQIRCSSNITGLLLTRDGGNSNNESEIFRPGGGDMRDNWRSELYKYKVVKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural definition of a conserved neutralization epitope on HIV-1 gp120.
pubmed doi rcsb
molecule tags Viral protein/immune system
source organism Human immunodeficiency virus 1
molecule keywords ENVELOPE GLYCOPROTEIN GP120
total genus 61
structure length 290
sequence length 317
ec nomenclature
pdb deposition date 2006-11-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 2ny7G00
2NXYA 4OLWG 4I53A 4DKVA 5F4RA 1G9NG 4LSUG 3HI1G 1YYLG 2NXZA 3TGQA 4YE4G 4I54A 4P9HG 5IGXG 4DVWA 4JB9G 4RFOG 4JPWG 4J6RG 1G9MG 5F4PA 1YYMG 5FECC 5CAYG 2B4CG 4OLZG 4OM0G 5CD5A 4R4FA 5TE7G 2QADA 4OLUG 5F4UA 3IDXG 4DKPA 5KJRG 4H8WG 5TE6G 2I60G 4R2GA 4JPVG 2NY0A 4RFNA 4YDKG 4JDTG 4XMPG 4DVTA 4OLYG 3TGRA 5F9OG 3NGBA 3FUSA 4S1SG 4LSTG 4DKQA 4R4NA 4XNZA 4DVVA 2NY2A 4KA2A 4JM2E 4DKOA 5FA2A 4JZWA 4XNYG 2NY4A 2NY5G 4YDIG 5F96G 4DVRG 4XVSG 4JKPG 2I5YG 4S1QG 5F9WA 4LSPG 4LSSG 3TGSA 5F4LA 3TIHA 2NY7G 4YFLE 3RJQA 4LSQG 4YDLA 3U7YG 2BF1A 3IDYA 4JZZA 4LSRG 4YDJG 3SE8G 4OLVG 5I9QA 4DVXA 1RZJG 2NY3A 4S1RG 5T33G 3LQAG 4XVTG 5TE4G 4LAJA 4OM1G 2NY1A 4RX4E 4RWYA 4DKUA 4DKRA 3TGTA 3JWDA 3SE9G 1GC1G 4OLXG 2NY6A 3JWOA 4LSVG 4K0AA 4RZ8A 4DVSA 1RZKG
chains in the Genus database with same CATH superfamily
2NXYA 4OLWG 4I53A 4DKVA 5F4RA 1G9NG 4LSUG 3HI1G 1YYLG 2NXZA 3TGQA 4YE4G 4I54A 4P9HG 5IGXG 4DVWA 4JB9G 4RFOG 4JPWG 4J6RG 1G9MG 5F4PA 1YYMG 5FECC 5CAYG 2B4CG 4OLZG 4OM0G 5CD5A 4R4FA 5TE7G 2QADA 4OLUG 5F4UA 3IDXG 4DKPA 5KJRG 4H8WG 5TE6G 2I60G 4R2GA 4JPVG 2NY0A 4RFNA 4YDKG 4JDTG 4XMPG 4DVTA 4OLYG 3TGRA 5F9OG 3NGBA 3FUSA 4S1SG 4LSTG 4DKQA 4R4NA 4XNZA 4DVVA 2NY2A 4KA2A 4JM2E 4DKOA 5FA2A 4JZWA 4XNYG 2NY4A 2NY5G 4YDIG 5F96G 4DVRG 4XVSG 4JKPG 2I5YG 4S1QG 5F9WA 4LSPG 4LSSG 3TGSA 5F4LA 3TIHA 2NY7G 4YFLE 3RJQA 4LSQG 4YDLA 3U7YG 2BF1A 3IDYA 4JZZA 4LSRG 4YDJG 3SE8G 4OLVG 5I9QA 4DVXA 1RZJG 2NY3A 4S1RG 5T33G 3LQAG 4XVTG 5TE4G 4LAJA 4OM1G 2NY1A 4RX4E 4RWYA 4DKUA 4DKRA 3TGTA 3JWDA 3SE9G 1GC1G 4OLXG 2NY6A 3JWOA 4LSVG 4K0AA 4RZ8A 4DVSA 1RZKG
chains in the Genus database with same CATH topology
2NXYA 4OLWG 4I53A 4DKVA 5F4RA 1G9NG 4LSUG 3HI1G 1YYLG 2NXZA 3TGQA 4YE4G 4I54A 4P9HG 5IGXG 4DVWA 4JB9G 4RFOG 4JPWG 4J6RG 1G9MG 5F4PA 1YYMG 5FECC 5CAYG 2B4CG 4OLZG 4OM0G 5CD5A 4R4FA 5TE7G 2QADA 4OLUG 5F4UA 3IDXG 4DKPA 5KJRG 4H8WG 5TE6G 2I60G 4R2GA 4JPVG 2NY0A 4RFNA 4YDKG 4JDTG 4XMPG 4DVTA 4OLYG 3TGRA 5F9OG 3NGBA 3FUSA 4S1SG 4LSTG 4DKQA 4R4NA 4XNZA 4DVVA 2NY2A 4KA2A 4JM2E 4DKOA 5FA2A 4JZWA 4XNYG 2NY4A 2NY5G 4YDIG 5F96G 4DVRG 4XVSG 4JKPG 2I5YG 4S1QG 5F9WA 4LSPG 4LSSG 3TGSA 5F4LA 3TIHA 2NY7G 4YFLE 3RJQA 4LSQG 4YDLA 3U7YG 2BF1A 3IDYA 4JZZA 4LSRG 4YDJG 3SE8G 4OLVG 5I9QA 4DVXA 1RZJG 2NY3A 4S1RG 5T33G 3LQAG 4XVTG 5TE4G 4LAJA 4OM1G 2NY1A 4RX4E 4RWYA 4DKUA 4DKRA 3TGTA 3JWDA 3SE9G 1GC1G 4OLXG 2NY6A 3JWOA 4LSVG 4K0AA 4RZ8A 4DVSA 1RZKG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NXY A;  4OLW G;  4I53 A;  4DKV A;  5F4R A;  1G9N G;  4LSU G;  3HI1 G;  1YYL G;  2NXZ A;  3TGQ A;  4YE4 G;  4I54 A;  4P9H G;  5IGX G;  4DVW A;  4JB9 G;  4RFO G;  4JPW G;  4J6R G;  1G9M G;  5F4P A;  1YYM G;  5FEC C;  5CAY G;  2B4C G;  4OLZ G;  4OM0 G;  5CD5 A;  4R4F A;  5TE7 G;  2QAD A;  4OLU G;  5F4U A;  3IDX G;  4DKP A;  5KJR G;  4H8W G;  5TE6 G;  2I60 G;  4R2G A;  4JPV G;  2NY0 A;  4RFN A;  4YDK G;  4JDT G;  4XMP G;  4DVT A;  4OLY G;  3TGR A;  5F9O G;  3NGB A;  3FUS A;  4S1S G;  4LST G;  4DKQ A;  4R4N A;  4XNZ A;  4DVV A;  2NY2 A;  4KA2 A;  4JM2 E;  4DKO A;  5FA2 A;  4JZW A;  4XNY G;  2NY4 A;  2NY5 G;  4YDI G;  5F96 G;  4DVR G;  4XVS G;  4JKP G;  2I5Y G;  4S1Q G;  5F9W A;  4LSP G;  4LSS G;  3TGS A;  5F4L A;  3TIH A;  2NY7 G;  4YFL E;  3RJQ A;  4LSQ G;  4YDL A;  3U7Y G;  2BF1 A;  3IDY A;  4JZZ A;  4LSR G;  4YDJ G;  3SE8 G;  4OLV G;  5I9Q A;  4DVX A;  1RZJ G;  2NY3 A;  4S1R G;  5T33 G;  3LQA G;  4XVT G;  5TE4 G;  4LAJ A;  4OM1 G;  2NY1 A;  4RX4 E;  4RWY A;  4DKU A;  4DKR A;  3TGT A;  3JWD A;  3SE9 G;  1GC1 G;  4OLX G;  2NY6 A;  3JWO A;  4LSV G;  4K0A A;  4RZ8 A;  4DVS A;  1RZK G; 
#chains in the Genus database with same CATH topology
 2NXY A;  4OLW G;  4I53 A;  4DKV A;  5F4R A;  1G9N G;  4LSU G;  3HI1 G;  1YYL G;  2NXZ A;  3TGQ A;  4YE4 G;  4I54 A;  4P9H G;  5IGX G;  4DVW A;  4JB9 G;  4RFO G;  4JPW G;  4J6R G;  1G9M G;  5F4P A;  1YYM G;  5FEC C;  5CAY G;  2B4C G;  4OLZ G;  4OM0 G;  5CD5 A;  4R4F A;  5TE7 G;  2QAD A;  4OLU G;  5F4U A;  3IDX G;  4DKP A;  5KJR G;  4H8W G;  5TE6 G;  2I60 G;  4R2G A;  4JPV G;  2NY0 A;  4RFN A;  4YDK G;  4JDT G;  4XMP G;  4DVT A;  4OLY G;  3TGR A;  5F9O G;  3NGB A;  3FUS A;  4S1S G;  4LST G;  4DKQ A;  4R4N A;  4XNZ A;  4DVV A;  2NY2 A;  4KA2 A;  4JM2 E;  4DKO A;  5FA2 A;  4JZW A;  4XNY G;  2NY4 A;  2NY5 G;  4YDI G;  5F96 G;  4DVR G;  4XVS G;  4JKP G;  2I5Y G;  4S1Q G;  5F9W A;  4LSP G;  4LSS G;  3TGS A;  5F4L A;  3TIH A;  2NY7 G;  4YFL E;  3RJQ A;  4LSQ G;  4YDL A;  3U7Y G;  2BF1 A;  3IDY A;  4JZZ A;  4LSR G;  4YDJ G;  3SE8 G;  4OLV G;  5I9Q A;  4DVX A;  1RZJ G;  2NY3 A;  4S1R G;  5T33 G;  3LQA G;  4XVT G;  5TE4 G;  4LAJ A;  4OM1 G;  2NY1 A;  4RX4 E;  4RWY A;  4DKU A;  4DKR A;  3TGT A;  3JWD A;  3SE9 G;  1GC1 G;  4OLX G;  2NY6 A;  3JWO A;  4LSV G;  4K0A A;  4RZ8 A;  4DVS A;  1RZK G; 
#chains in the Genus database with same CATH homology
 2NXY A;  4OLW G;  4I53 A;  4DKV A;  5F4R A;  1G9N G;  4LSU G;  3HI1 G;  1YYL G;  2NXZ A;  3TGQ A;  4YE4 G;  4I54 A;  4P9H G;  5IGX G;  4DVW A;  4JB9 G;  4RFO G;  4JPW G;  4J6R G;  1G9M G;  5F4P A;  1YYM G;  5FEC C;  5CAY G;  2B4C G;  4OLZ G;  4OM0 G;  5CD5 A;  4R4F A;  5TE7 G;  2QAD A;  4OLU G;  5F4U A;  3IDX G;  4DKP A;  5KJR G;  4H8W G;  5TE6 G;  2I60 G;  4R2G A;  4JPV G;  2NY0 A;  4RFN A;  4YDK G;  4JDT G;  4XMP G;  4DVT A;  4OLY G;  3TGR A;  5F9O G;  3NGB A;  3FUS A;  4S1S G;  4LST G;  4DKQ A;  4R4N A;  4XNZ A;  4DVV A;  2NY2 A;  4KA2 A;  4JM2 E;  4DKO A;  5FA2 A;  4JZW A;  4XNY G;  2NY4 A;  2NY5 G;  4YDI G;  5F96 G;  4DVR G;  4XVS G;  4JKP G;  2I5Y G;  4S1Q G;  5F9W A;  4LSP G;  4LSS G;  3TGS A;  5F4L A;  3TIH A;  2NY7 G;  4YFL E;  3RJQ A;  4LSQ G;  4YDL A;  3U7Y G;  2BF1 A;  3IDY A;  4JZZ A;  4LSR G;  4YDJ G;  3SE8 G;  4OLV G;  5I9Q A;  4DVX A;  1RZJ G;  2NY3 A;  4S1R G;  5T33 G;  3LQA G;  4XVT G;  5TE4 G;  4LAJ A;  4OM1 G;  2NY1 A;  4RX4 E;  4RWY A;  4DKU A;  4DKR A;  3TGT A;  3JWD A;  3SE9 G;  1GC1 G;  4OLX G;  2NY6 A;  3JWO A;  4LSV G;  4K0A A;  4RZ8 A;  4DVS A;  1RZK G; 
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similar chains in the Genus database (?% sequence similarity)
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