2ONIA

Catalytic domain of the human nedd4-like e3 ligase
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
378
structure length
377
Chain Sequence
LYFQGSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFEEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMFCIDEENFGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title NEDD4-like E3 Ubiquitin-protein Ligase
rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase NEDD4-like protein
total genus 113
structure length 377
sequence length 378
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2007-01-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2160.10 Alpha Beta 2-Layer Sandwich Hect, E3 ligase catalytic domain Hect, E3 ligase catalytic domain 2oniA02
3.30.2410.10 Alpha Beta 2-Layer Sandwich Hect, E3 ligase catalytic fold Hect, E3 ligase catalytic domain 2oniA03
3.90.1750.10 Alpha Beta Alpha-Beta Complex Hect, E3 ligase catalytic domain fold Hect, E3 ligase catalytic domains 2oniA01
3JW0C 1D5FA 2XBBA 2XBFA 3H1DA 1ZVDA 3JVZC 1ND7A 2ONIA 3PT3A 1C4ZA 3OLMA 3G1NA
chains in the Genus database with same CATH superfamily
3JW0C 1D5FA 2XBBA 2XBFA 3H1DA 1ZVDA 3JVZC 1ND7A 2ONIA 3PT3A 1C4ZA 3OLMA 3G1NA
chains in the Genus database with same CATH topology
3JW0C 1D5FA 2XBBA 2XBFA 3H1DA 1ZVDA 3JVZC 1ND7A 2ONIA 3PT3A 1C4ZA 3OLMA 3G1NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3JW0 C;  1D5F A;  2XBB A;  2XBF A;  3H1D A;  1ZVD A;  3JVZ C;  1ND7 A;  2ONI A;  3PT3 A;  1C4Z A;  3OLM A;  3G1N A; 
#chains in the Genus database with same CATH topology
 3JW0 C;  1D5F A;  2XBB A;  2XBF A;  3H1D A;  1ZVD A;  3JVZ C;  1ND7 A;  2ONI A;  3PT3 A;  1C4Z A;  3OLM A;  3G1N A; 
#chains in the Genus database with same CATH homology
 3JW0 C;  1D5F A;  2XBB A;  2XBF A;  3H1D A;  1ZVD A;  3JVZ C;  1ND7 A;  2ONI A;  3PT3 A;  1C4Z A;  3OLM A;  3G1N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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