2PW8I

Crystal structure of sulfo-hirudin complexed to thrombin
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
65
structure length
61
Chain Sequence
LTYTDCTESGQNLCLCEGSNVCGQGNKCILGSDGEKNQCVTGEGTPKPQSGDFEEIPEELQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin.
pubmed doi rcsb
molecule tags Hydrolase
source organism Hirudo medicinalis
molecule keywords Thrombin light chain
total genus 9
structure length 61
sequence length 65
ec nomenclature
pdb deposition date 2007-05-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.10.10 Mainly Beta Distorted Sandwich Thrombin Inhibitor (Hirudin); Chain I Thrombin Inhibitor (Hirudin), subunit I 2pw8I00
6HIRA 2JOOA 2HIRA 5HIRA 4HTCI 1E0FI 4MLFD 4HIRA 1HRTI 2PW8I 1HICA
chains in the Genus database with same CATH superfamily
6HIRA 2JOOA 2HIRA 5HIRA 4HTCI 1E0FI 4MLFD 4HIRA 1HRTI 2PW8I 1HICA
chains in the Genus database with same CATH topology
6HIRA 2JOOA 2HIRA 5HIRA 4HTCI 1E0FI 4MLFD 4HIRA 1HRTI 2PW8I 1HICA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 6HIR A;  2JOO A;  2HIR A;  5HIR A;  4HTC I;  1E0F I;  4MLF D;  4HIR A;  1HRT I;  2PW8 I;  1HIC A; 
#chains in the Genus database with same CATH topology
 6HIR A;  2JOO A;  2HIR A;  5HIR A;  4HTC I;  1E0F I;  4MLF D;  4HIR A;  1HRT I;  2PW8 I;  1HIC A; 
#chains in the Genus database with same CATH homology
 6HIR A;  2JOO A;  2HIR A;  5HIR A;  4HTC I;  1E0F I;  4MLF D;  4HIR A;  1HRT I;  2PW8 I;  1HIC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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