2PY4A

Full length structure of the mycobacterium tuberculosis dutpase complexed with magnesium and alpha,beta-imido-dutp.
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
153
structure length
153
Chain Sequence
STTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEAGLASTSRGDGGHGSSGGHASL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 23
structure length 153
sequence length 153
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2007-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 2py4A00
3H6XA 4GCYA 3ZF6A 1DUPA 3MBQA 4B0HA 2OKBA 5ECTA 1RNJA 3CA9A 1F7NA 1XS6A 3MDXA 3H6DA 2HXBA 4GV8A 3TPSA 4WRKA 3T60A 3T70A 5CCOA 3TPNA 1Q5UX 2BSYA 2WE0A 3ZF5A 3ZF1A 1SM8A 1MQ7A 2HRMA 2OKEA 1DUCA 2PY4A 5EDDA 1PKJA 1DUDA 2J4QA 2WE3A 2ZDCA 1DUTA 2Y1TA 4AOOA 3ECYA 1SJNA 2D4LA 3HZAA 2BAZA 2OKDA 3TRLA 2XCDA 3TSLA 2Y8CA 1SNFA 2BT1A 1XS4A 3HHQA 2QLPA 5F9KA 1PKKA 4XJCA 3ARAA 3TTAA 4GK6A 2HXDA 3ARNA 2D4MA 2OL0A 1EUWA 2R9QA 4APZ1 2HQUA 3TRNA 1F7RA 3TP1A 3SO2A 3I93A 2YZJA 3TQZA 2XCEA 3TPYA 2V9XA 3ZF2A 2QXXA 3TQ4A 2OL1A 3ZF3A 3ZEZA 2WE2A 3T64A 1SLHA 2HR6A 2WE1A 4OOPA 3C3IA 3LOJA 5CCTA 3TQ3A 1VYQA 2XX6A 3ZF0A 1SYLA 4LHRA 3TQ5A 3TS6A 3C2TA 2J4HA 4A6AA 4DHKA 4OOQA 3GF0A 1SEHA 4AOZA 1Q5HA 1XS1A 1F7DA 3ZF4A 1OGHA 1RN8A 2D4NA 1F7QA 2XY3A 3LQWA 4AO5A 1PKHA 3KM3A 1F7KA 1SMCA 1EU5A 1F7OA 3EHWA 1DUNA 1F7PA 3F4FA 1SIXA 3P48A 3T6YA 3TPWA 2PC5A
chains in the Genus database with same CATH superfamily
3H6XA 4GCYA 3ZF6A 1DUPA 3MBQA 4B0HA 2OKBA 5ECTA 1RNJA 3CA9A 1F7NA 1XS6A 3MDXA 3H6DA 2HXBA 4GV8A 3TPSA 4WRKA 3T60A 3T70A 5CCOA 3TPNA 1Q5UX 2BSYA 2WE0A 3ZF5A 3ZF1A 1SM8A 1MQ7A 2HRMA 2OKEA 1DUCA 2PY4A 5EDDA 1PKJA 1DUDA 2J4QA 2WE3A 2ZDCA 1DUTA 2Y1TA 4AOOA 1SJNA 3ECYA 2D4LA 3HZAA 2BAZA 2OKDA 3TRLA 2XCDA 3TSLA 2Y8CA 1SNFA 2BT1A 1XS4A 3HHQA 2QLPA 5F9KA 1PKKA 4XJCA 3ARAA 3TTAA 4GK6A 2HXDA 3ARNA 2D4MA 2OL0A 1EUWA 2R9QA 4APZ1 2HQUA 3TRNA 1F7RA 3TP1A 3SO2A 3I93A 2YZJA 3TQZA 2XCEA 3TPYA 2V9XA 3ZF2A 2QXXA 3TQ4A 2OL1A 3ZF3A 3ZEZA 2WE2A 3T64A 1SLHA 2HR6A 2WE1A 4OOPA 3C3IA 3LOJA 5CCTA 3TQ3A 1VYQA 2XX6A 3ZF0A 1SYLA 4LHRA 3TQ5A 3TS6A 3C2TA 2J4HA 4A6AA 4DHKA 4OOQA 3GF0A 1SEHA 4AOZA 1Q5HA 1XS1A 1F7DA 3ZF4A 1OGHA 1RN8A 2D4NA 1F7QA 2XY3A 3LQWA 4AO5A 1PKHA 3KM3A 1F7KA 1SMCA 1TULA 1EU5A 1F7OA 3EHWA 1DUNA 1F7PA 3F4FA 1SIXA 3P48A 3T6YA 3TPWA 2PC5A
chains in the Genus database with same CATH topology
3H6XA 4GCYA 3ZF6A 1DUPA 3MBQA 4B0HA 2OKBA 5ECTA 1RNJA 3CA9A 1F7NA 1XS6A 3MDXA 3H6DA 2HXBA 4GV8A 3TPSA 4WRKA 3T60A 3T70A 5CCOA 3TPNA 1Q5UX 2BSYA 2WE0A 3ZF5A 3ZF1A 1SM8A 1MQ7A 2HRMA 2OKEA 1DUCA 2PY4A 5EDDA 1PKJA 1DUDA 2J4QA 2WE3A 2ZDCA 1DUTA 2Y1TA 4AOOA 3ECYA 1SJNA 2D4LA 3HZAA 2BAZA 2OKDA 3TRLA 2XCDA 3TSLA 2Y8CA 1SNFA 2BT1A 1XS4A 3HHQA 2QLPA 5F9KA 1PKKA 4XJCA 3ARAA 3TTAA 4GK6A 2HXDA 3ARNA 2D4MA 2OL0A 1EUWA 2R9QA 4APZ1 2HQUA 3TRNA 1F7RA 3TP1A 3SO2A 3I93A 2YZJA 3TQZA 2XCEA 3TPYA 2V9XA 3ZF2A 2QXXA 3TQ4A 2OL1A 3ZF3A 3ZEZA 2WE2A 3T64A 1SLHA 2HR6A 2WE1A 4OOPA 3C3IA 3LOJA 5CCTA 3TQ3A 1VYQA 2XX6A 3ZF0A 1SYLA 4LHRA 3TQ5A 3TS6A 3C2TA 2J4HA 4A6AA 4DHKA 4OOQA 3GF0A 1SEHA 4AOZA 1Q5HA 1XS1A 1F7DA 3ZF4A 1OGHA 1RN8A 2D4NA 1F7QA 2XY3A 3LQWA 4AO5A 1PKHA 3KM3A 1F7KA 1SMCA 1EU5A 1F7OA 3EHWA 1DUNA 1F7PA 3F4FA 1SIXA 3P48A 3T6YA 3TPWA 2PC5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H6X A;  4GCY A;  3ZF6 A;  1DUP A;  3MBQ A;  4B0H A;  2OKB A;  5ECT A;  1RNJ A;  3CA9 A;  1F7N A;  1XS6 A;  3MDX A;  3H6D A;  2HXB A;  4GV8 A;  3TPS A;  4WRK A;  3T60 A;  3T70 A;  5CCO A;  3TPN A;  1Q5U X;  2BSY A;  2WE0 A;  3ZF5 A;  3ZF1 A;  1SM8 A;  1MQ7 A;  2HRM A;  2OKE A;  1DUC A;  2PY4 A;  5EDD A;  1PKJ A;  1DUD A;  2J4Q A;  2WE3 A;  2ZDC A;  1DUT A;  2Y1T A;  4AOO A;  3ECY A;  1SJN A;  2D4L A;  3HZA A;  2BAZ A;  2OKD A;  3TRL A;  2XCD A;  3TSL A;  2Y8C A;  1SNF A;  2BT1 A;  1XS4 A;  3HHQ A;  2QLP A;  5F9K A;  1PKK A;  4XJC A;  3ARA A;  3TTA A;  4GK6 A;  2HXD A;  3ARN A;  2D4M A;  2OL0 A;  1EUW A;  2R9Q A;  4APZ 1;  2HQU A;  3TRN A;  1F7R A;  3TP1 A;  3SO2 A;  3I93 A;  2YZJ A;  3TQZ A;  2XCE A;  3TPY A;  2V9X A;  3ZF2 A;  2QXX A;  3TQ4 A;  2OL1 A;  3ZF3 A;  3ZEZ A;  2WE2 A;  3T64 A;  1SLH A;  2HR6 A;  2WE1 A;  4OOP A;  3C3I A;  3LOJ A;  5CCT A;  3TQ3 A;  1VYQ A;  2XX6 A;  3ZF0 A;  1SYL A;  4LHR A;  3TQ5 A;  3TS6 A;  3C2T A;  2J4H A;  4A6A A;  4DHK A;  4OOQ A;  3GF0 A;  1SEH A;  4AOZ A;  1Q5H A;  1XS1 A;  1F7D A;  3ZF4 A;  1OGH A;  1RN8 A;  2D4N A;  1F7Q A;  2XY3 A;  3LQW A;  4AO5 A;  1PKH A;  3KM3 A;  1F7K A;  1SMC A;  1EU5 A;  1F7O A;  3EHW A;  1DUN A;  1F7P A;  3F4F A;  1SIX A;  3P48 A;  3T6Y A;  3TPW A;  2PC5 A; 
#chains in the Genus database with same CATH topology
 3H6X A;  4GCY A;  3ZF6 A;  1DUP A;  3MBQ A;  4B0H A;  2OKB A;  5ECT A;  1RNJ A;  3CA9 A;  1F7N A;  1XS6 A;  3MDX A;  3H6D A;  2HXB A;  4GV8 A;  3TPS A;  4WRK A;  3T60 A;  3T70 A;  5CCO A;  3TPN A;  1Q5U X;  2BSY A;  2WE0 A;  3ZF5 A;  3ZF1 A;  1SM8 A;  1MQ7 A;  2HRM A;  2OKE A;  1DUC A;  2PY4 A;  5EDD A;  1PKJ A;  1DUD A;  2J4Q A;  2WE3 A;  2ZDC A;  1DUT A;  2Y1T A;  4AOO A;  1SJN A;  3ECY A;  2D4L A;  3HZA A;  2BAZ A;  2OKD A;  3TRL A;  2XCD A;  3TSL A;  2Y8C A;  1SNF A;  2BT1 A;  1XS4 A;  3HHQ A;  2QLP A;  5F9K A;  1PKK A;  4XJC A;  3ARA A;  3TTA A;  4GK6 A;  2HXD A;  3ARN A;  2D4M A;  2OL0 A;  1EUW A;  2R9Q A;  4APZ 1;  2HQU A;  3TRN A;  1F7R A;  3TP1 A;  3SO2 A;  3I93 A;  2YZJ A;  3TQZ A;  2XCE A;  3TPY A;  2V9X A;  3ZF2 A;  2QXX A;  3TQ4 A;  2OL1 A;  3ZF3 A;  3ZEZ A;  2WE2 A;  3T64 A;  1SLH A;  2HR6 A;  2WE1 A;  4OOP A;  3C3I A;  3LOJ A;  5CCT A;  3TQ3 A;  1VYQ A;  2XX6 A;  3ZF0 A;  1SYL A;  4LHR A;  3TQ5 A;  3TS6 A;  3C2T A;  2J4H A;  4A6A A;  4DHK A;  4OOQ A;  3GF0 A;  1SEH A;  4AOZ A;  1Q5H A;  1XS1 A;  1F7D A;  3ZF4 A;  1OGH A;  1RN8 A;  2D4N A;  1F7Q A;  2XY3 A;  3LQW A;  4AO5 A;  1PKH A;  3KM3 A;  1F7K A;  1SMC A;  1TUL A;  1EU5 A;  1F7O A;  3EHW A;  1DUN A;  1F7P A;  3F4F A;  1SIX A;  3P48 A;  3T6Y A;  3TPW A;  2PC5 A; 
#chains in the Genus database with same CATH homology
 3H6X A;  4GCY A;  3ZF6 A;  1DUP A;  3MBQ A;  4B0H A;  2OKB A;  5ECT A;  1RNJ A;  3CA9 A;  1F7N A;  1XS6 A;  3MDX A;  3H6D A;  2HXB A;  4GV8 A;  3TPS A;  4WRK A;  3T60 A;  3T70 A;  5CCO A;  3TPN A;  1Q5U X;  2BSY A;  2WE0 A;  3ZF5 A;  3ZF1 A;  1SM8 A;  1MQ7 A;  2HRM A;  2OKE A;  1DUC A;  2PY4 A;  5EDD A;  1PKJ A;  1DUD A;  2J4Q A;  2WE3 A;  2ZDC A;  1DUT A;  2Y1T A;  4AOO A;  3ECY A;  1SJN A;  2D4L A;  3HZA A;  2BAZ A;  2OKD A;  3TRL A;  2XCD A;  3TSL A;  2Y8C A;  1SNF A;  2BT1 A;  1XS4 A;  3HHQ A;  2QLP A;  5F9K A;  1PKK A;  4XJC A;  3ARA A;  3TTA A;  4GK6 A;  2HXD A;  3ARN A;  2D4M A;  2OL0 A;  1EUW A;  2R9Q A;  4APZ 1;  2HQU A;  3TRN A;  1F7R A;  3TP1 A;  3SO2 A;  3I93 A;  2YZJ A;  3TQZ A;  2XCE A;  3TPY A;  2V9X A;  3ZF2 A;  2QXX A;  3TQ4 A;  2OL1 A;  3ZF3 A;  3ZEZ A;  2WE2 A;  3T64 A;  1SLH A;  2HR6 A;  2WE1 A;  4OOP A;  3C3I A;  3LOJ A;  5CCT A;  3TQ3 A;  1VYQ A;  2XX6 A;  3ZF0 A;  1SYL A;  4LHR A;  3TQ5 A;  3TS6 A;  3C2T A;  2J4H A;  4A6A A;  4DHK A;  4OOQ A;  3GF0 A;  1SEH A;  4AOZ A;  1Q5H A;  1XS1 A;  1F7D A;  3ZF4 A;  1OGH A;  1RN8 A;  2D4N A;  1F7Q A;  2XY3 A;  3LQW A;  4AO5 A;  1PKH A;  3KM3 A;  1F7K A;  1SMC A;  1EU5 A;  1F7O A;  3EHW A;  1DUN A;  1F7P A;  3F4F A;  1SIX A;  3P48 A;  3T6Y A;  3TPW A;  2PC5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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