2PYSA

Crystal structure of a five site mutated cyanovirin-n with a mannose dimer bound at 1.8 a resolution
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
101
structure length
101
Chain Sequence
GNFSQACYNSAIQGSVLTSTCIRTNGGYNTSSIDLNSVIENVDGSLKWQGSNFIETCRNTQLAGSSELAAECKTRAQQFVSTKINLDDHIAAIDGTLKYEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Monovalent Mutant of Cyanovirin-N Provides Insight into the Role of Multiple Interactions with gp120 for Antiviral Activity.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Nostoc ellipsosporum
molecule keywords Cyanovirin-N
total genus 26
structure length 101
sequence length 101
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08881 CVNH CVNH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.60.10 Mainly Beta Roll HIV-inactivating Protein, Cyanovirin-n Cyanovirin-N 2pysA00
3CZZA 3HNUX 2RDKA 2JZJA 3S3ZA 1L5BA 4J4FA 1IIYA 3S3YA 3EZMA 3GXZA 5C8OA 2L9YA 2Y1SA 1LOMA 2EZMA 1J4VA 4J4CA 2JZLA 2KJLA 2L2FA 1L5EA 2PYSA 3LHCA 2EZNA 2JZKA 1N02A 4J4EA 5C8QB 3GXYA 2RP3A 5C8PA 3HNXA 2Z21A 2YHHA 3HP8A
chains in the Genus database with same CATH superfamily
3CZZA 3HNUX 2RDKA 2JZJA 3S3ZA 1L5BA 4J4FA 1IIYA 3S3YA 3EZMA 3GXZA 5C8OA 2L9YA 2Y1SA 1LOMA 2EZMA 1J4VA 4J4CA 2JZLA 2KJLA 2L2FA 1L5EA 2PYSA 3LHCA 2EZNA 2JZKA 1N02A 4J4EA 5C8QB 3GXYA 2RP3A 5C8PA 3HNXA 2Z21A 2YHHA 3HP8A
chains in the Genus database with same CATH topology
3CZZA 3HNUX 2RDKA 2JZJA 3S3ZA 1L5BA 4J4FA 1IIYA 3S3YA 3EZMA 3GXZA 5C8OA 2L9YA 2Y1SA 1LOMA 2EZMA 1J4VA 4J4CA 2JZLA 2KJLA 2L2FA 1L5EA 2PYSA 3LHCA 2EZNA 2JZKA 1N02A 4J4EA 5C8QB 3GXYA 2RP3A 5C8PA 3HNXA 2Z21A 2YHHA 3HP8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CZZ A;  3HNU X;  2RDK A;  2JZJ A;  3S3Z A;  1L5B A;  4J4F A;  1IIY A;  3S3Y A;  3EZM A;  3GXZ A;  5C8O A;  2L9Y A;  2Y1S A;  1LOM A;  2EZM A;  1J4V A;  4J4C A;  2JZL A;  2KJL A;  2L2F A;  1L5E A;  2PYS A;  3LHC A;  2EZN A;  2JZK A;  1N02 A;  4J4E A;  5C8Q B;  3GXY A;  2RP3 A;  5C8P A;  3HNX A;  2Z21 A;  2YHH A;  3HP8 A; 
#chains in the Genus database with same CATH topology
 3CZZ A;  3HNU X;  2RDK A;  2JZJ A;  3S3Z A;  1L5B A;  4J4F A;  1IIY A;  3S3Y A;  3EZM A;  3GXZ A;  5C8O A;  2L9Y A;  2Y1S A;  1LOM A;  2EZM A;  1J4V A;  4J4C A;  2JZL A;  2KJL A;  2L2F A;  1L5E A;  2PYS A;  3LHC A;  2EZN A;  2JZK A;  1N02 A;  4J4E A;  5C8Q B;  3GXY A;  2RP3 A;  5C8P A;  3HNX A;  2Z21 A;  2YHH A;  3HP8 A; 
#chains in the Genus database with same CATH homology
 3CZZ A;  3HNU X;  2RDK A;  2JZJ A;  3S3Z A;  1L5B A;  4J4F A;  1IIY A;  3S3Y A;  3EZM A;  3GXZ A;  5C8O A;  2L9Y A;  2Y1S A;  1LOM A;  2EZM A;  1J4V A;  4J4C A;  2JZL A;  2KJL A;  2L2F A;  1L5E A;  2PYS A;  3LHC A;  2EZN A;  2JZK A;  1N02 A;  4J4E A;  5C8Q B;  3GXY A;  2RP3 A;  5C8P A;  3HNX A;  2Z21 A;  2YHH A;  3HP8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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