2QEXC

Negamycin binds to the wall of the nascent chain exit tunnel of the 50s ribosomal subunit
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKLDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 62
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2007-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 2qexC00
3J7YF 3CCEC 1YHQC 1M90E 1VQ7C 1YJNC 1VQLC 1VQ8C 3CC2C 3CCLC 2QA4C 1VQ5C 2QEXC 1K73E 1DMGA 1W2BC 1K8AE 1VQPC 1YJ9C 2OTLC 3I55C 1K9ME 1KQSC 3CCMC 1YJWC 1QVGC 1N8RE 3CC7C 1VQKC 3I56C 1VQ6C 1VQMC 1Q81E 3CMAC 1Q86E 1VQOC 1Q7YE 1VQNC 3CC4C 3CD6C 1YI2C 1JJ2C 3CCUC 3CPWC 1KC8E 3CCVC 3CMEC 5DM7C 1QVFC 1Q82E 3G4SC 4V19F 1YIJC 2OTJC 3G6EC 3G71C 3OW2C 1S72C 1VQ4C 1YITC 3CCQC 1KD1E 1VQ9C 3CCSC 3CXCC 1NJIE 1M1KE 3CCRC 3CCJC
chains in the Genus database with same CATH superfamily
3J7YF 3CCEC 1YHQC 1M90E 1VQ7C 1YJNC 1VQLC 1VQ8C 3CC2C 3CCLC 2QA4C 1VQ5C 2QEXC 1K73E 1DMGA 1W2BC 1K8AE 1VQPC 1YJ9C 2OTLC 3I55C 1K9ME 1KQSC 3CCMC 1YJWC 1QVGC 1N8RE 3CC7C 1VQKC 3I56C 1VQ6C 1VQMC 1Q81E 3CMAC 1Q86E 1VQOC 1Q7YE 1VQNC 3CC4C 3CD6C 1YI2C 1JJ2C 3CCUC 3CPWC 1KC8E 3CCVC 3CMEC 5DM7C 1QVFC 1Q82E 3G4SC 4V19F 1YIJC 2OTJC 3G6EC 3G71C 3OW2C 1S72C 1VQ4C 1YITC 3CCQC 1KD1E 1VQ9C 3CCSC 3CXCC 1NJIE 1M1KE 3CCRC 3CCJC
chains in the Genus database with same CATH topology
3J7YF 3CCEC 1YHQC 1M90E 1VQ7C 1YJNC 1VQLC 1VQ8C 3CC2C 3CCLC 2QA4C 1VQ5C 2QEXC 1K73E 1DMGA 1W2BC 1K8AE 1VQPC 1YJ9C 2OTLC 3I55C 1K9ME 1KQSC 3CCMC 1YJWC 1QVGC 1N8RE 3CC7C 1VQKC 3I56C 1VQ6C 1VQMC 1Q81E 3CMAC 1Q86E 1VQOC 1Q7YE 1VQNC 3CC4C 3CD6C 1YI2C 1JJ2C 3CCUC 3CPWC 1KC8E 3CCVC 3CMEC 5DM7C 1QVFC 1Q82E 3G4SC 4V19F 1YIJC 2OTJC 3G6EC 3G71C 3OW2C 1S72C 1VQ4C 1YITC 3CCQC 1KD1E 1VQ9C 3CCSC 3CXCC 1NJIE 1M1KE 3CCRC 3CCJC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3J7Y F;  3CCE C;  1YHQ C;  1M90 E;  1VQ7 C;  1YJN C;  1VQL C;  1VQ8 C;  3CC2 C;  3CCL C;  2QA4 C;  1VQ5 C;  2QEX C;  1K73 E;  1DMG A;  1W2B C;  1K8A E;  1VQP C;  1YJ9 C;  2OTL C;  3I55 C;  1K9M E;  1KQS C;  3CCM C;  1YJW C;  1QVG C;  1N8R E;  3CC7 C;  1VQK C;  3I56 C;  1VQ6 C;  1VQM C;  1Q81 E;  3CMA C;  1Q86 E;  1VQO C;  1Q7Y E;  1VQN C;  3CC4 C;  3CD6 C;  1YI2 C;  1JJ2 C;  3CCU C;  3CPW C;  1KC8 E;  3CCV C;  3CME C;  5DM7 C;  1QVF C;  1Q82 E;  3G4S C;  4V19 F;  1YIJ C;  2OTJ C;  3G6E C;  3G71 C;  3OW2 C;  1S72 C;  1VQ4 C;  1YIT C;  3CCQ C;  1KD1 E;  1VQ9 C;  3CCS C;  3CXC C;  1NJI E;  1M1K E;  3CCR C;  3CCJ C; 
#chains in the Genus database with same CATH topology
 3J7Y F;  3CCE C;  1YHQ C;  1M90 E;  1VQ7 C;  1YJN C;  1VQL C;  1VQ8 C;  3CC2 C;  3CCL C;  2QA4 C;  1VQ5 C;  2QEX C;  1K73 E;  1DMG A;  1W2B C;  1K8A E;  1VQP C;  1YJ9 C;  2OTL C;  3I55 C;  1K9M E;  1KQS C;  3CCM C;  1YJW C;  1QVG C;  1N8R E;  3CC7 C;  1VQK C;  3I56 C;  1VQ6 C;  1VQM C;  1Q81 E;  3CMA C;  1Q86 E;  1VQO C;  1Q7Y E;  1VQN C;  3CC4 C;  3CD6 C;  1YI2 C;  1JJ2 C;  3CCU C;  3CPW C;  1KC8 E;  3CCV C;  3CME C;  5DM7 C;  1QVF C;  1Q82 E;  3G4S C;  4V19 F;  1YIJ C;  2OTJ C;  3G6E C;  3G71 C;  3OW2 C;  1S72 C;  1VQ4 C;  1YIT C;  3CCQ C;  1KD1 E;  1VQ9 C;  3CCS C;  3CXC C;  1NJI E;  1M1K E;  3CCR C;  3CCJ C; 
#chains in the Genus database with same CATH homology
 3J7Y F;  3CCE C;  1YHQ C;  1M90 E;  1VQ7 C;  1YJN C;  1VQL C;  1VQ8 C;  3CC2 C;  3CCL C;  2QA4 C;  1VQ5 C;  2QEX C;  1K73 E;  1DMG A;  1W2B C;  1K8A E;  1VQP C;  1YJ9 C;  2OTL C;  3I55 C;  1K9M E;  1KQS C;  3CCM C;  1YJW C;  1QVG C;  1N8R E;  3CC7 C;  1VQK C;  3I56 C;  1VQ6 C;  1VQM C;  1Q81 E;  3CMA C;  1Q86 E;  1VQO C;  1Q7Y E;  1VQN C;  3CC4 C;  3CD6 C;  1YI2 C;  1JJ2 C;  3CCU C;  3CPW C;  1KC8 E;  3CCV C;  3CME C;  5DM7 C;  1QVF C;  1Q82 E;  3G4S C;  4V19 F;  1YIJ C;  2OTJ C;  3G6E C;  3G71 C;  3OW2 C;  1S72 C;  1VQ4 C;  1YIT C;  3CCQ C;  1KD1 E;  1VQ9 C;  3CCS C;  3CXC C;  1NJI E;  1M1K E;  3CCR C;  3CCJ C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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