2VDEA

Crystal structure of the open state of tolc outer membrane component of mutlidrug efflux pumps
Total Genus 156
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
156
sequence length
428
structure length
428
Chain Sequence
ENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSKWRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNARAQYDTVLANELTARNNLDNAVEQLRQITGNYYPELAALNVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTASTGISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGFSVGTETIVDVLDATTTLYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Assembly and Channel Opening in a Bacterial Drug Efflux Machine.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords OUTER MEMBRANE PROTEIN TOLC
total genus 156
structure length 428
sequence length 428
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2007-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02321 OEP Outer membrane efflux protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1600.10 Mainly Alpha Up-down Bundle Outer membrane efflux proteins (OEP) Outer membrane efflux proteins (OEP) 2vdeA00
4MT4A 5IUYA 3D5KA 2VDDA 5BUNA 1EK9A 4MT0A 4K7RA 5AZOA 1YC9A 2XMNA 3PIKA 4K34A 5AZPA 1TQQA 2VDEA 2WMZA 5AZSA 4Y1KA 4K7KA 1WP1A
chains in the Genus database with same CATH superfamily
4MT4A 5IUYA 3D5KA 2VDDA 5BUNA 1EK9A 4MT0A 4K7RA 5AZOA 1YC9A 2XMNA 3PIKA 4K34A 5AZPA 1TQQA 2VDEA 2WMZA 5AZSA 4Y1KA 4K7KA 1WP1A
chains in the Genus database with same CATH topology
4MT4A 5IUYA 3D5KA 2VDDA 5BUNA 1EK9A 4MT0A 4K7RA 5AZOA 1YC9A 2XMNA 3PIKA 4K34A 5AZPA 1TQQA 2VDEA 2WMZA 5AZSA 4Y1KA 4K7KA 1WP1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MT4 A;  5IUY A;  3D5K A;  2VDD A;  5BUN A;  1EK9 A;  4MT0 A;  4K7R A;  5AZO A;  1YC9 A;  2XMN A;  3PIK A;  4K34 A;  5AZP A;  1TQQ A;  2VDE A;  2WMZ A;  5AZS A;  4Y1K A;  4K7K A;  1WP1 A; 
#chains in the Genus database with same CATH topology
 4MT4 A;  5IUY A;  3D5K A;  2VDD A;  5BUN A;  1EK9 A;  4MT0 A;  4K7R A;  5AZO A;  1YC9 A;  2XMN A;  3PIK A;  4K34 A;  5AZP A;  1TQQ A;  2VDE A;  2WMZ A;  5AZS A;  4Y1K A;  4K7K A;  1WP1 A; 
#chains in the Genus database with same CATH homology
 4MT4 A;  5IUY A;  3D5K A;  2VDD A;  5BUN A;  1EK9 A;  4MT0 A;  4K7R A;  5AZO A;  1YC9 A;  2XMN A;  3PIK A;  4K34 A;  5AZP A;  1TQQ A;  2VDE A;  2WMZ A;  5AZS A;  4Y1K A;  4K7K A;  1WP1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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