2W3NA

Structure and inhibition of the co2-sensing carbonic anhydrase can2 from the pathogenic fungus cryptococcus neoformans
Total Genus 70
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
230
structure length
230
Chain Sequence
PFHAEPLKPSDEIDMDLGHSVAAQKFKEIREVLEGNRYWARKVTSEEPEFMAEQVKGQAPNFLWIGCADSRVPEVTIMARKPGDVFVQRNVANQFKPEDDSSQALLNYAIMNVGVTHVMVVGHTGCGGCIAAFDQPLPTEENPGGTPLVRYLEPIIRLKHSLPEGSDVNDLIKENVKMAVKNVVNSPTIQGAWEQARKGEFREVFVHGWLYDLSTGNIVDLNVTQGPHPF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure and inhibition of the CO2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformans.
pubmed doi rcsb
molecule tags Lyase
source organism Cryptococcus neoformans
molecule keywords CARBONIC ANHYDRASE 2
total genus 70
structure length 230
sequence length 230
chains with identical sequence B, C
ec nomenclature ec 4.2.1.1: Carbonic anhydrase.
pdb deposition date 2008-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00484 Pro_CA Carbonic anhydrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1050.10 Alpha Beta 3-Layer(aba) Sandwich Beta-carbonic Anhydrase; Chain A Carbonic anhydrase 2w3nA02
4ZNZA 3E31A 5SWCA 4YF5A 2A8CA 3UCNA 5JJ8A 3LASA 3TENA 4YF6A 2A5VA 3E2AA 3VRKA 3EYXA 1I6OA 2W3QA 1T75A 3E1VA 1G5CA 4WAMA 3E1WA 3UCKA 3UCJA 4O1JA 3E3GA 5BQ1A 3E2WA 3E2XA 2ESFA 2W3NA 1YM3A 4RXYA 1I6PA 3VQJA 3TEOA 3E28A 5CXKA 4WAJA 3QY1A 3UCOA 4YF4A 4O1KA 1DDZA 3UCMA 3MF3A 3E3IA 2A8DA 3E24A 1YLKA 4WAKA 3E3FA 1EKJA
chains in the Genus database with same CATH superfamily
4ZNZA 3E31A 5SWCA 4YF5A 2A8CA 3UCNA 5JJ8A 3LASA 3TENA 4YF6A 2A5VA 3E2AA 3VRKA 3EYXA 1I6OA 2W3QA 1T75A 3E1VA 1G5CA 4WAMA 3E1WA 3UCKA 3UCJA 4O1JA 3E3GA 5BQ1A 3E2WA 3E2XA 2ESFA 2W3NA 1YM3A 4RXYA 1I6PA 3VQJA 3TEOA 3E28A 5CXKA 4WAJA 3QY1A 3UCOA 4YF4A 4O1KA 1DDZA 3UCMA 3MF3A 3E3IA 2A8DA 3E24A 1YLKA 4WAKA 3E3FA 1EKJA
chains in the Genus database with same CATH topology
4ZNZA 3E31A 5SWCA 4YF5A 2A8CA 3UCNA 5JJ8A 3LASA 3TENA 4YF6A 2A5VA 3E2AA 3VRKA 3EYXA 1I6OA 2W3QA 1T75A 3E1VA 1G5CA 4WAMA 3E1WA 3UCKA 3UCJA 4O1JA 3E3GA 5BQ1A 3E2WA 3E2XA 2ESFA 2W3NA 1YM3A 4RXYA 1I6PA 3VQJA 3TEOA 3E28A 5CXKA 4WAJA 3QY1A 3UCOA 4YF4A 4O1KA 1DDZA 3UCMA 3MF3A 3E3IA 2A8DA 3E24A 1YLKA 4WAKA 3E3FA 1EKJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZNZ A;  3E31 A;  5SWC A;  4YF5 A;  2A8C A;  3UCN A;  5JJ8 A;  3LAS A;  3TEN A;  4YF6 A;  2A5V A;  3E2A A;  3VRK A;  3EYX A;  1I6O A;  2W3Q A;  1T75 A;  3E1V A;  1G5C A;  4WAM A;  3E1W A;  3UCK A;  3UCJ A;  4O1J A;  3E3G A;  5BQ1 A;  3E2W A;  3E2X A;  2ESF A;  2W3N A;  1YM3 A;  4RXY A;  1I6P A;  3VQJ A;  3TEO A;  3E28 A;  5CXK A;  4WAJ A;  3QY1 A;  3UCO A;  4YF4 A;  4O1K A;  1DDZ A;  3UCM A;  3MF3 A;  3E3I A;  2A8D A;  3E24 A;  1YLK A;  4WAK A;  3E3F A;  1EKJ A; 
#chains in the Genus database with same CATH topology
 4ZNZ A;  3E31 A;  5SWC A;  4YF5 A;  2A8C A;  3UCN A;  5JJ8 A;  3LAS A;  3TEN A;  4YF6 A;  2A5V A;  3E2A A;  3VRK A;  3EYX A;  1I6O A;  2W3Q A;  1T75 A;  3E1V A;  1G5C A;  4WAM A;  3E1W A;  3UCK A;  3UCJ A;  4O1J A;  3E3G A;  5BQ1 A;  3E2W A;  3E2X A;  2ESF A;  2W3N A;  1YM3 A;  4RXY A;  1I6P A;  3VQJ A;  3TEO A;  3E28 A;  5CXK A;  4WAJ A;  3QY1 A;  3UCO A;  4YF4 A;  4O1K A;  1DDZ A;  3UCM A;  3MF3 A;  3E3I A;  2A8D A;  3E24 A;  1YLK A;  4WAK A;  3E3F A;  1EKJ A; 
#chains in the Genus database with same CATH homology
 4ZNZ A;  3E31 A;  5SWC A;  4YF5 A;  2A8C A;  3UCN A;  5JJ8 A;  3LAS A;  3TEN A;  4YF6 A;  2A5V A;  3E2A A;  3VRK A;  3EYX A;  1I6O A;  2W3Q A;  1T75 A;  3E1V A;  1G5C A;  4WAM A;  3E1W A;  3UCK A;  3UCJ A;  4O1J A;  3E3G A;  5BQ1 A;  3E2W A;  3E2X A;  2ESF A;  2W3N A;  1YM3 A;  4RXY A;  1I6P A;  3VQJ A;  3TEO A;  3E28 A;  5CXK A;  4WAJ A;  3QY1 A;  3UCO A;  4YF4 A;  4O1K A;  1DDZ A;  3UCM A;  3MF3 A;  3E3I A;  2A8D A;  3E24 A;  1YLK A;  4WAK A;  3E3F A;  1EKJ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...