2W3QA

Structure and inhibition of the co2-sensing carbonic anhydrase can2 from the pathogenic fungus cryptococcus neoformans
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
234
structure length
229
Chain Sequence
PLGSMPFHAEPLKPSDEIDMDLGHSVAAQKFKEIREVLEGNRYWARKVTSEEPEFMAEQVKGQAPNFLWIGCADSRVPEVTIMARKPGDVFVQRNVANQFKPEDDSSQALLNYAIMNVGVTHVMVVGHTGCGGCIAAFDQPLPGGTPLVRYLEPIIRLKHSLPEGSDVNDLIKENVKMAVKNVVNSPTIQGAWEQARKGEFREVFVHGWLYDLSTGNIVDLNVTQGPHP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and Inhibition of the Co(2)-Sensing Carbonic Anhydrase Can2 from the Pathogenic Fungus Cryptococcus Neoformans.
pubmed doi rcsb
molecule tags Lyase
source organism Cryptococcus neoformans
molecule keywords CARBONIC ANHYDRASE 2
total genus 73
structure length 229
sequence length 234
ec nomenclature ec 4.2.1.1: Carbonic anhydrase.
pdb deposition date 2008-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00484 Pro_CA Carbonic anhydrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1050.10 Alpha Beta 3-Layer(aba) Sandwich Beta-carbonic Anhydrase; Chain A Carbonic anhydrase 2w3qA02
4O1JA 3E2AA 3QY1A 2ESFA 3VRKA 4RXYA 1DDZA 2W3QA 2A5VA 3UCNA 3E3GA 3TEOA 3EYXA 3E31A 3E1WA 1YM3A 2W3NA 3E3FA 3TENA 3UCJA 3UCOA 5CXKA 4YF4A 1YLKA 1T75A 3E3IA 5JJ8A 2A8CA 4WAJA 3MF3A 3E28A 4YF5A 3E24A 4WAKA 3LASA 4WAMA 1EKJA 3E2XA 5SWCA 3UCKA 4YF6A 3UCMA 4ZNZA 3VQJA 1G5CA 3E1VA 1I6OA 3E2WA 4O1KA 5BQ1A 2A8DA 1I6PA
chains in the Genus database with same CATH superfamily
4O1JA 3E2AA 3QY1A 2ESFA 3VRKA 4RXYA 1DDZA 2W3QA 2A5VA 3UCNA 3E3GA 3TEOA 3EYXA 3E31A 3E1WA 1YM3A 2W3NA 3E3FA 3TENA 3UCJA 3UCOA 5CXKA 4YF4A 1YLKA 1T75A 3E3IA 5JJ8A 2A8CA 4WAJA 3MF3A 3E28A 4YF5A 3E24A 4WAKA 3LASA 4WAMA 1EKJA 3E2XA 5SWCA 3UCKA 4YF6A 3UCMA 4ZNZA 3VQJA 1G5CA 3E1VA 1I6OA 3E2WA 4O1KA 5BQ1A 2A8DA 1I6PA
chains in the Genus database with same CATH topology
4O1JA 3E2AA 3QY1A 2ESFA 3VRKA 4RXYA 1DDZA 2W3QA 2A5VA 3UCNA 3E3GA 3TEOA 3EYXA 3E31A 3E1WA 1YM3A 2W3NA 3E3FA 3TENA 3UCJA 3UCOA 5CXKA 4YF4A 1YLKA 1T75A 3E3IA 5JJ8A 2A8CA 4WAJA 3MF3A 3E28A 4YF5A 3E24A 4WAKA 3LASA 4WAMA 1EKJA 3E2XA 5SWCA 3UCKA 4YF6A 3UCMA 4ZNZA 3VQJA 1G5CA 3E1VA 1I6OA 3E2WA 4O1KA 5BQ1A 2A8DA 1I6PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O1J A;  3E2A A;  3QY1 A;  2ESF A;  3VRK A;  4RXY A;  1DDZ A;  2W3Q A;  2A5V A;  3UCN A;  3E3G A;  3TEO A;  3EYX A;  3E31 A;  3E1W A;  1YM3 A;  2W3N A;  3E3F A;  3TEN A;  3UCJ A;  3UCO A;  5CXK A;  4YF4 A;  1YLK A;  1T75 A;  3E3I A;  5JJ8 A;  2A8C A;  4WAJ A;  3MF3 A;  3E28 A;  4YF5 A;  3E24 A;  4WAK A;  3LAS A;  4WAM A;  1EKJ A;  3E2X A;  5SWC A;  3UCK A;  4YF6 A;  3UCM A;  4ZNZ A;  3VQJ A;  1G5C A;  3E1V A;  1I6O A;  3E2W A;  4O1K A;  5BQ1 A;  2A8D A;  1I6P A; 
#chains in the Genus database with same CATH topology
 4O1J A;  3E2A A;  3QY1 A;  2ESF A;  3VRK A;  4RXY A;  1DDZ A;  2W3Q A;  2A5V A;  3UCN A;  3E3G A;  3TEO A;  3EYX A;  3E31 A;  3E1W A;  1YM3 A;  2W3N A;  3E3F A;  3TEN A;  3UCJ A;  3UCO A;  5CXK A;  4YF4 A;  1YLK A;  1T75 A;  3E3I A;  5JJ8 A;  2A8C A;  4WAJ A;  3MF3 A;  3E28 A;  4YF5 A;  3E24 A;  4WAK A;  3LAS A;  4WAM A;  1EKJ A;  3E2X A;  5SWC A;  3UCK A;  4YF6 A;  3UCM A;  4ZNZ A;  3VQJ A;  1G5C A;  3E1V A;  1I6O A;  3E2W A;  4O1K A;  5BQ1 A;  2A8D A;  1I6P A; 
#chains in the Genus database with same CATH homology
 4O1J A;  3E2A A;  3QY1 A;  2ESF A;  3VRK A;  4RXY A;  1DDZ A;  2W3Q A;  2A5V A;  3UCN A;  3E3G A;  3TEO A;  3EYX A;  3E31 A;  3E1W A;  1YM3 A;  2W3N A;  3E3F A;  3TEN A;  3UCJ A;  3UCO A;  5CXK A;  4YF4 A;  1YLK A;  1T75 A;  3E3I A;  5JJ8 A;  2A8C A;  4WAJ A;  3MF3 A;  3E28 A;  4YF5 A;  3E24 A;  4WAK A;  3LAS A;  4WAM A;  1EKJ A;  3E2X A;  5SWC A;  3UCK A;  4YF6 A;  3UCM A;  4ZNZ A;  3VQJ A;  1G5C A;  3E1V A;  1I6O A;  3E2W A;  4O1K A;  5BQ1 A;  2A8D A;  1I6P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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