2W97B

Crystal structure of eif4e bound to glycerol and eif4g1 peptide
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
188
structure length
177
Chain Sequence
NPEHYIKHPLQNRWALWFFKKNLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKTTKNRFVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallization of Eif4E Complexed with Eif4Gi Peptide and Glycerol Reveals Distinct Structural Differences Around the CAP-Binding Site.
pubmed rcsb
molecule tags Translation
source organism Homo sapiens
molecule keywords EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
total genus 54
structure length 177
sequence length 188
ec nomenclature
pdb deposition date 2009-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01652 IF4E Eukaryotic initiation factor 4E
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.760.10 Alpha Beta 2-Layer Sandwich RNA Cap, Translation Initiation Factor Eif4e RNA Cap, Translation Initiation Factor Eif4e 2w97B00
3AM7A 3TF2A 3U7XA 2V8YA 1IPBA 5EKVA 2W97B 4AZAA 2JGCA 5EIRA 1EJ4A 1IPCA 4B6VA 1AP8A 3M93A 2WMCA 3HXIA 1EJHA 5T48A 5GW6A 3M94A 5EI3A 1EJ1A 1ZTPA 4UEAA 1RF8A 4DUMA 4DT6A 4UEDA 2JGBA 2IDRA 4UECA 5T47A 4UE8A 2Q4KA 1WKWA 2W97A 3HXGA 2V8WA 2GPQA 4UE9A 1L8BA 4BEAA 4TQBA 5ABXA 2V8XA 4B6UA 5T46A 4AXGA 4TQCA 4TPWA 5EHCA 5BXVA 5ABVA 5ABUA 5ABYA 4UEBA 2IDVA
chains in the Genus database with same CATH superfamily
3AM7A 3TF2A 3U7XA 2V8YA 1IPBA 5EKVA 2W97B 4AZAA 2JGCA 5EIRA 1EJ4A 1IPCA 4B6VA 1AP8A 3M93A 2WMCA 3HXIA 1EJHA 5T48A 5GW6A 3M94A 5EI3A 1EJ1A 1ZTPA 4UEAA 1RF8A 4DUMA 4DT6A 4UEDA 2JGBA 2IDRA 4UECA 5T47A 4UE8A 2Q4KA 1WKWA 2W97A 3HXGA 2V8WA 2GPQA 4UE9A 1L8BA 4BEAA 4TQBA 5ABXA 2V8XA 4B6UA 5T46A 4AXGA 4TQCA 4TPWA 5EHCA 5BXVA 5ABVA 5ABUA 5ABYA 4UEBA 2IDVA
chains in the Genus database with same CATH topology
3AM7A 3TF2A 3U7XA 2V8YA 1IPBA 5EKVA 2W97B 4AZAA 2JGCA 5EIRA 1EJ4A 1IPCA 4B6VA 1AP8A 3M93A 2WMCA 3HXIA 1EJHA 5T48A 5GW6A 3M94A 5EI3A 1EJ1A 1ZTPA 4UEAA 1RF8A 4DUMA 4DT6A 4UEDA 2JGBA 2IDRA 4UECA 5T47A 4UE8A 2Q4KA 1WKWA 2W97A 3HXGA 2V8WA 2GPQA 4UE9A 1L8BA 4BEAA 4TQBA 5ABXA 2V8XA 4B6UA 5T46A 4AXGA 4TQCA 4TPWA 5EHCA 5BXVA 5ABVA 5ABUA 5ABYA 4UEBA 2IDVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AM7 A;  3TF2 A;  3U7X A;  2V8Y A;  1IPB A;  5EKV A;  2W97 B;  4AZA A;  2JGC A;  5EIR A;  1EJ4 A;  1IPC A;  4B6V A;  1AP8 A;  3M93 A;  2WMC A;  3HXI A;  1EJH A;  5T48 A;  5GW6 A;  3M94 A;  5EI3 A;  1EJ1 A;  1ZTP A;  4UEA A;  1RF8 A;  4DUM A;  4DT6 A;  4UED A;  2JGB A;  2IDR A;  4UEC A;  5T47 A;  4UE8 A;  2Q4K A;  1WKW A;  2W97 A;  3HXG A;  2V8W A;  2GPQ A;  4UE9 A;  1L8B A;  4BEA A;  4TQB A;  5ABX A;  2V8X A;  4B6U A;  5T46 A;  4AXG A;  4TQC A;  4TPW A;  5EHC A;  5BXV A;  5ABV A;  5ABU A;  5ABY A;  4UEB A;  2IDV A; 
#chains in the Genus database with same CATH topology
 3AM7 A;  3TF2 A;  3U7X A;  2V8Y A;  1IPB A;  5EKV A;  2W97 B;  4AZA A;  2JGC A;  5EIR A;  1EJ4 A;  1IPC A;  4B6V A;  1AP8 A;  3M93 A;  2WMC A;  3HXI A;  1EJH A;  5T48 A;  5GW6 A;  3M94 A;  5EI3 A;  1EJ1 A;  1ZTP A;  4UEA A;  1RF8 A;  4DUM A;  4DT6 A;  4UED A;  2JGB A;  2IDR A;  4UEC A;  5T47 A;  4UE8 A;  2Q4K A;  1WKW A;  2W97 A;  3HXG A;  2V8W A;  2GPQ A;  4UE9 A;  1L8B A;  4BEA A;  4TQB A;  5ABX A;  2V8X A;  4B6U A;  5T46 A;  4AXG A;  4TQC A;  4TPW A;  5EHC A;  5BXV A;  5ABV A;  5ABU A;  5ABY A;  4UEB A;  2IDV A; 
#chains in the Genus database with same CATH homology
 3AM7 A;  3TF2 A;  3U7X A;  2V8Y A;  1IPB A;  5EKV A;  2W97 B;  4AZA A;  2JGC A;  5EIR A;  1EJ4 A;  1IPC A;  4B6V A;  1AP8 A;  3M93 A;  2WMC A;  3HXI A;  1EJH A;  5T48 A;  5GW6 A;  3M94 A;  5EI3 A;  1EJ1 A;  1ZTP A;  4UEA A;  1RF8 A;  4DUM A;  4DT6 A;  4UED A;  2JGB A;  2IDR A;  4UEC A;  5T47 A;  4UE8 A;  2Q4K A;  1WKW A;  2W97 A;  3HXG A;  2V8W A;  2GPQ A;  4UE9 A;  1L8B A;  4BEA A;  4TQB A;  5ABX A;  2V8X A;  4B6U A;  5T46 A;  4AXG A;  4TQC A;  4TPW A;  5EHC A;  5BXV A;  5ABV A;  5ABU A;  5ABY A;  4UEB A;  2IDV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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