2WE1A

Ebv dutpase mutant asp131asn with bound dump
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
253
structure length
245
Chain Sequence
CPHIRYAFQNDKLLLQQASVGRLTLVNKTTILLRPMKTTTVDLGLYARPPEGHGLMLWGSTSRPVTSHVGIIDPGYTGELRLILQNQRRYNSTLRPSELKIHLAAFRYATPQMGPINPGNVGLDVSLPKDLALFPHQTVSVTLTVPPPSIPHHRPTIFGRSGLAMQGILVKPCRWRRGGVDVSLTNFSDQTVFLNKYRRFCQLVYLHKHHLTSFYSPHSDAGVLGPRSLFRWASCTFEEVPSLAM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Flexible Motif V of Epstein-Barr Virus Deoxyuridine 5'-Triphosphate Pyrophosphatase is Essential for Catalysis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Human herpesvirus 4
molecule keywords DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE
total genus 41
structure length 245
sequence length 253
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2009-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 2we1A01
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 2we1A02
4WRKA 1DUPA 3T60A 3ZEZA 3ZF1A 2OKEA 4OOQA 1SJNA 4GV8A 2Y8CA 3T70A 3GF0A 2XY3A 1XS6A 1RN8A 2WE1A 2BSYA 3ZF5A 1F7PA 2HR6A 3ZF2A 2XCDA 5F9KA 3TQ4A 3TRNA 3TQZA 3EHWA 3H6XA 2XX6A 1SLHA 4GCYA 3P48A 3ZF6A 2J4HA 2R9QA 3T6YA 5EDDA 3TPNA 4XJCA 3ZF3A 2QXXA 1F7RA 5ECTA 1DUTA 2OL1A 2D4MA 3MDXA 2OKDA 3TQ5A 3MBQA 2WE2A 4OOPA 1SEHA 1Q5UX 2OL0A 4B0HA 3HZAA 3I93A 1SM8A 3ECYA 1RNJA 2WE3A 3H6DA 2BAZA 3SO2A 1XS4A 2PC5A 2QLPA 3ARNA 1DUDA 2OKBA 3HHQA 1F7DA 1DUCA 3KM3A 1SNFA 3TRLA 3T64A 1F7NA 1Q5HA 2Y1TA 2D4LA 2V9XA 3TPWA 1SYLA 3TPYA 3C3IA 1F7OA 1DUNA 2HXBA 3ZF0A 3LOJA 4APZ1 1F7KA 2HXDA 1SMCA 4AOZA 2BT1A 2WE0A 1F7QA 3ARAA 3TTAA 3TP1A 4DHKA 4LHRA 2ZDCA 3TQ3A 2XCEA 1PKJA 4GK6A 4AOOA 2YZJA 3LQWA 4A6AA 4AO5A 3F4FA 5CCOA 1XS1A 2J4QA 1SIXA 1EUWA 3C2TA 3TPSA 1EU5A 3CA9A 1VYQA 1MQ7A 2HRMA 1OGHA 2PY4A 5CCTA 2HQUA 3ZF4A 3TSLA 1PKHA 1PKKA 3TS6A 2D4NA
chains in the Genus database with same CATH superfamily
4WRKA 1DUPA 3T60A 3ZEZA 3ZF1A 2OKEA 4OOQA 1SJNA 4GV8A 2Y8CA 3T70A 3GF0A 2XY3A 1XS6A 1RN8A 2WE1A 2BSYA 3ZF5A 1F7PA 2HR6A 3ZF2A 2XCDA 5F9KA 3TQ4A 3TRNA 3TQZA 3EHWA 3H6XA 2XX6A 1SLHA 4GCYA 3P48A 3ZF6A 2J4HA 2R9QA 3T6YA 5EDDA 3TPNA 4XJCA 3ZF3A 2QXXA 1F7RA 5ECTA 1DUTA 2OL1A 2D4MA 3MDXA 2OKDA 3TQ5A 3MBQA 2WE2A 4OOPA 1SEHA 1Q5UX 2OL0A 4B0HA 3HZAA 3I93A 1SM8A 3ECYA 1RNJA 2WE3A 3H6DA 2BAZA 3SO2A 1XS4A 2PC5A 2QLPA 3ARNA 1DUDA 2OKBA 3HHQA 1F7DA 1DUCA 3KM3A 1SNFA 3TRLA 3T64A 1F7NA 1Q5HA 2Y1TA 2D4LA 2V9XA 3TPWA 1SYLA 3TPYA 3C3IA 1F7OA 1DUNA 1TULA 2HXBA 3ZF0A 3LOJA 4APZ1 1F7KA 2HXDA 1SMCA 4AOZA 2BT1A 2WE0A 1F7QA 3ARAA 3TTAA 3TP1A 4DHKA 4LHRA 2ZDCA 3TQ3A 2XCEA 1PKJA 4GK6A 4AOOA 2YZJA 3LQWA 4A6AA 4AO5A 3F4FA 5CCOA 1XS1A 2J4QA 1SIXA 1EUWA 3C2TA 3TPSA 1EU5A 3CA9A 1VYQA 1MQ7A 2HRMA 1OGHA 2PY4A 5CCTA 2HQUA 3ZF4A 3TSLA 1PKHA 1PKKA 3TS6A 2D4NA
chains in the Genus database with same CATH topology
4WRKA 1DUPA 3T60A 3ZEZA 3ZF1A 2OKEA 4OOQA 1SJNA 4GV8A 2Y8CA 3T70A 3GF0A 2XY3A 1XS6A 1RN8A 2WE1A 2BSYA 3ZF5A 1F7PA 2HR6A 3ZF2A 2XCDA 5F9KA 3TQ4A 3TRNA 3TQZA 3EHWA 3H6XA 2XX6A 1SLHA 4GCYA 3P48A 3ZF6A 2J4HA 2R9QA 3T6YA 5EDDA 3TPNA 4XJCA 3ZF3A 2QXXA 1F7RA 5ECTA 1DUTA 2OL1A 2D4MA 3MDXA 2OKDA 3TQ5A 3MBQA 2WE2A 4OOPA 1SEHA 1Q5UX 2OL0A 4B0HA 3HZAA 3I93A 1SM8A 3ECYA 1RNJA 2WE3A 3H6DA 2BAZA 3SO2A 1XS4A 2PC5A 2QLPA 3ARNA 1DUDA 2OKBA 3HHQA 1F7DA 1DUCA 3KM3A 1SNFA 3TRLA 3T64A 1F7NA 1Q5HA 2Y1TA 2D4LA 2V9XA 3TPWA 1SYLA 3TPYA 3C3IA 1F7OA 1DUNA 2HXBA 3ZF0A 3LOJA 4APZ1 1F7KA 2HXDA 1SMCA 4AOZA 2BT1A 2WE0A 1F7QA 3ARAA 3TTAA 3TP1A 4DHKA 4LHRA 2ZDCA 3TQ3A 2XCEA 1PKJA 4GK6A 4AOOA 2YZJA 3LQWA 4A6AA 4AO5A 3F4FA 5CCOA 1XS1A 2J4QA 1SIXA 1EUWA 3C2TA 3TPSA 1EU5A 3CA9A 1VYQA 1MQ7A 2HRMA 1OGHA 2PY4A 5CCTA 2HQUA 3ZF4A 3TSLA 1PKHA 1PKKA 3TS6A 2D4NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WRK A;  1DUP A;  3T60 A;  3ZEZ A;  3ZF1 A;  2OKE A;  4OOQ A;  1SJN A;  4GV8 A;  2Y8C A;  3T70 A;  3GF0 A;  2XY3 A;  1XS6 A;  1RN8 A;  2WE1 A;  2BSY A;  3ZF5 A;  1F7P A;  2HR6 A;  3ZF2 A;  2XCD A;  5F9K A;  3TQ4 A;  3TRN A;  3TQZ A;  3EHW A;  3H6X A;  2XX6 A;  1SLH A;  4GCY A;  3P48 A;  3ZF6 A;  2J4H A;  2R9Q A;  3T6Y A;  5EDD A;  3TPN A;  4XJC A;  3ZF3 A;  2QXX A;  1F7R A;  5ECT A;  1DUT A;  2OL1 A;  2D4M A;  3MDX A;  2OKD A;  3TQ5 A;  3MBQ A;  2WE2 A;  4OOP A;  1SEH A;  1Q5U X;  2OL0 A;  4B0H A;  3HZA A;  3I93 A;  1SM8 A;  3ECY A;  1RNJ A;  2WE3 A;  3H6D A;  2BAZ A;  3SO2 A;  1XS4 A;  2PC5 A;  2QLP A;  3ARN A;  1DUD A;  2OKB A;  3HHQ A;  1F7D A;  1DUC A;  3KM3 A;  1SNF A;  3TRL A;  3T64 A;  1F7N A;  1Q5H A;  2Y1T A;  2D4L A;  2V9X A;  3TPW A;  1SYL A;  3TPY A;  3C3I A;  1F7O A;  1DUN A;  2HXB A;  3ZF0 A;  3LOJ A;  4APZ 1;  1F7K A;  2HXD A;  1SMC A;  4AOZ A;  2BT1 A;  2WE0 A;  1F7Q A;  3ARA A;  3TTA A;  3TP1 A;  4DHK A;  4LHR A;  2ZDC A;  3TQ3 A;  2XCE A;  1PKJ A;  4GK6 A;  4AOO A;  2YZJ A;  3LQW A;  4A6A A;  4AO5 A;  3F4F A;  5CCO A;  1XS1 A;  2J4Q A;  1SIX A;  1EUW A;  3C2T A;  3TPS A;  1EU5 A;  3CA9 A;  1VYQ A;  1MQ7 A;  2HRM A;  1OGH A;  2PY4 A;  5CCT A;  2HQU A;  3ZF4 A;  3TSL A;  1PKH A;  1PKK A;  3TS6 A;  2D4N A; 
#chains in the Genus database with same CATH topology
 4WRK A;  1DUP A;  3T60 A;  3ZEZ A;  3ZF1 A;  2OKE A;  4OOQ A;  1SJN A;  4GV8 A;  2Y8C A;  3T70 A;  3GF0 A;  2XY3 A;  1XS6 A;  1RN8 A;  2WE1 A;  2BSY A;  3ZF5 A;  1F7P A;  2HR6 A;  3ZF2 A;  2XCD A;  5F9K A;  3TQ4 A;  3TRN A;  3TQZ A;  3EHW A;  3H6X A;  2XX6 A;  1SLH A;  4GCY A;  3P48 A;  3ZF6 A;  2J4H A;  2R9Q A;  3T6Y A;  5EDD A;  3TPN A;  4XJC A;  3ZF3 A;  2QXX A;  1F7R A;  5ECT A;  1DUT A;  2OL1 A;  2D4M A;  3MDX A;  2OKD A;  3TQ5 A;  3MBQ A;  2WE2 A;  4OOP A;  1SEH A;  1Q5U X;  2OL0 A;  4B0H A;  3HZA A;  3I93 A;  1SM8 A;  3ECY A;  1RNJ A;  2WE3 A;  3H6D A;  2BAZ A;  3SO2 A;  1XS4 A;  2PC5 A;  2QLP A;  3ARN A;  1DUD A;  2OKB A;  3HHQ A;  1F7D A;  1DUC A;  3KM3 A;  1SNF A;  3TRL A;  3T64 A;  1F7N A;  1Q5H A;  2Y1T A;  2D4L A;  2V9X A;  3TPW A;  1SYL A;  3TPY A;  3C3I A;  1F7O A;  1DUN A;  1TUL A;  2HXB A;  3ZF0 A;  3LOJ A;  4APZ 1;  1F7K A;  2HXD A;  1SMC A;  4AOZ A;  2BT1 A;  2WE0 A;  1F7Q A;  3ARA A;  3TTA A;  3TP1 A;  4DHK A;  4LHR A;  2ZDC A;  3TQ3 A;  2XCE A;  1PKJ A;  4GK6 A;  4AOO A;  2YZJ A;  3LQW A;  4A6A A;  4AO5 A;  3F4F A;  5CCO A;  1XS1 A;  2J4Q A;  1SIX A;  1EUW A;  3C2T A;  3TPS A;  1EU5 A;  3CA9 A;  1VYQ A;  1MQ7 A;  2HRM A;  1OGH A;  2PY4 A;  5CCT A;  2HQU A;  3ZF4 A;  3TSL A;  1PKH A;  1PKK A;  3TS6 A;  2D4N A; 
#chains in the Genus database with same CATH homology
 4WRK A;  1DUP A;  3T60 A;  3ZEZ A;  3ZF1 A;  2OKE A;  4OOQ A;  1SJN A;  4GV8 A;  2Y8C A;  3T70 A;  3GF0 A;  2XY3 A;  1XS6 A;  1RN8 A;  2WE1 A;  2BSY A;  3ZF5 A;  1F7P A;  2HR6 A;  3ZF2 A;  2XCD A;  5F9K A;  3TQ4 A;  3TRN A;  3TQZ A;  3EHW A;  3H6X A;  2XX6 A;  1SLH A;  4GCY A;  3P48 A;  3ZF6 A;  2J4H A;  2R9Q A;  3T6Y A;  5EDD A;  3TPN A;  4XJC A;  3ZF3 A;  2QXX A;  1F7R A;  5ECT A;  1DUT A;  2OL1 A;  2D4M A;  3MDX A;  2OKD A;  3TQ5 A;  3MBQ A;  2WE2 A;  4OOP A;  1SEH A;  1Q5U X;  2OL0 A;  4B0H A;  3HZA A;  3I93 A;  1SM8 A;  3ECY A;  1RNJ A;  2WE3 A;  3H6D A;  2BAZ A;  3SO2 A;  1XS4 A;  2PC5 A;  2QLP A;  3ARN A;  1DUD A;  2OKB A;  3HHQ A;  1F7D A;  1DUC A;  3KM3 A;  1SNF A;  3TRL A;  3T64 A;  1F7N A;  1Q5H A;  2Y1T A;  2D4L A;  2V9X A;  3TPW A;  1SYL A;  3TPY A;  3C3I A;  1F7O A;  1DUN A;  2HXB A;  3ZF0 A;  3LOJ A;  4APZ 1;  1F7K A;  2HXD A;  1SMC A;  4AOZ A;  2BT1 A;  2WE0 A;  1F7Q A;  3ARA A;  3TTA A;  3TP1 A;  4DHK A;  4LHR A;  2ZDC A;  3TQ3 A;  2XCE A;  1PKJ A;  4GK6 A;  4AOO A;  2YZJ A;  3LQW A;  4A6A A;  4AO5 A;  3F4F A;  5CCO A;  1XS1 A;  2J4Q A;  1SIX A;  1EUW A;  3C2T A;  3TPS A;  1EU5 A;  3CA9 A;  1VYQ A;  1MQ7 A;  2HRM A;  1OGH A;  2PY4 A;  5CCT A;  2HQU A;  3ZF4 A;  3TSL A;  1PKH A;  1PKK A;  3TS6 A;  2D4N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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