2WMLA

Crystal structure of a mammalian sialyltransferase
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
285
structure length
276
Chain Sequence
YRPCTCTRCIEEQRVSAWFDERFNRSMQPLLTAKNAHLEEDTYKWWLRLQREKKPNNLNDTIRELFQVVPGNVDPLLEKRLVSCRRCAVVGNSGNLKESYYGPQIDSHDFVLRMNKAPTEGFEADVGSKTTHHFVYPESFRELAQEVSMILVPFKTTDLEWVISATTTGRISHTYVPVPAKIKVKKEKILIYHPAFIKYVFDRWLQGHGRYPSTGILSVIFSLHICDEVDLYGFGADSKGNWHHYWEKTGVHDGDFESNVTTILASINKIRIFKGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insight Into Mammalian Sialyltransferases.
pubmed doi rcsb
molecule tags Transferase
source organism Sus scrofa
molecule keywords CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE -ALPHA-2\,3-SIALY
total genus 94
structure length 276
sequence length 285
ec nomenclature ec 2.4.99.4: Beta-galactoside alpha-2,3-sialyltransferase.
pdb deposition date 2009-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00777 Glyco_transf_29 Glycosyltransferase family 29 (sialyltransferase)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1480.20 Alpha Beta Alpha-Beta Complex sialyltransferase cstii, chain A sialyltransferase cstii, chain A 2wmlA00
4JS2A 5BO6A 5BO7A 5BO9A 5BO8A 2WNBA 4MPSA 2WNFA 2WMLA 4JS1A 5CXYA
chains in the Genus database with same CATH superfamily
2P56A 5BO7A 2P2VA 2X62A 5BO8A 2WNBA 2WMLA 2X61A 2DRJA 1RO7A 5BO6A 4MPSA 2X63A 4JS1A 4JS2A 1RO8A 5BO9A 2WNFA 2WQQA 5CXYA
chains in the Genus database with same CATH topology
4JS2A 5BO6A 5BO7A 5BO9A 5BO8A 2WNBA 4MPSA 2WNFA 2WMLA 4JS1A 5CXYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JS2 A;  5BO6 A;  5BO7 A;  5BO9 A;  5BO8 A;  2WNB A;  4MPS A;  2WNF A;  2WML A;  4JS1 A;  5CXY A; 
#chains in the Genus database with same CATH topology
 2P56 A;  5BO7 A;  2P2V A;  2X62 A;  5BO8 A;  2WNB A;  2WML A;  2X61 A;  2DRJ A;  1RO7 A;  5BO6 A;  4MPS A;  2X63 A;  4JS1 A;  4JS2 A;  1RO8 A;  5BO9 A;  2WNF A;  2WQQ A;  5CXY A; 
#chains in the Genus database with same CATH homology
 4JS2 A;  5BO6 A;  5BO7 A;  5BO9 A;  5BO8 A;  2WNB A;  4MPS A;  2WNF A;  2WML A;  4JS1 A;  5CXY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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