2WNBA

Crystal structure of a mammalian sialyltransferase in complex with disaccharide and cmp
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
284
structure length
273
Chain Sequence
RPCTCTRCIEEQRVSAWFDERFNRSMQPLLTAKNAHLEEDTYKWWLRLQREKQPNNLNDTIRELFQVVPGNVDPLLEKRLVSCRRCAVVGNSGNLKESYYGPQIDSHDFVLRMNKAPTEGFEADVGSKTTHHFVYPESFRELAQEVSMILVPFKTTDLEWVISATTTGRISHTYVPVPAKIKVKKEKILIYHPAFIKYVFDRWLQGHGRYPSTGILSVIFSLHICDEVDLYGFGADSKGNWHHYWEGVHDGDFESNVTTILASINKIRIFKGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insight Into Mammalian Sialyltransferases.
pubmed doi rcsb
molecule tags Transferase
source organism Sus scrofa
molecule keywords CYTIDINE-5'-MONOPHOSPHATE
total genus 94
structure length 273
sequence length 284
ec nomenclature ec 2.4.99.4: Beta-galactoside alpha-2,3-sialyltransferase.
pdb deposition date 2009-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00777 Glyco_transf_29 Glycosyltransferase family 29 (sialyltransferase)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1480.20 Alpha Beta Alpha-Beta Complex sialyltransferase cstii, chain A sialyltransferase cstii, chain A 2wnbA00
2WNBA 5BO6A 5BO9A 2WNFA 5BO7A 2WMLA 5CXYA 4JS1A 4JS2A 4MPSA 5BO8A
chains in the Genus database with same CATH superfamily
2WMLA 2WQQA 2X63A 2X61A 2P2VA 2P56A 2WNBA 1RO7A 5BO9A 2WNFA 5BO7A 5BO8A 2X62A 4MPSA 2DRJA 4JS2A 5BO6A 5CXYA 4JS1A 1RO8A
chains in the Genus database with same CATH topology
2WNBA 5BO6A 5BO9A 2WNFA 5BO7A 2WMLA 5CXYA 4JS1A 4JS2A 4MPSA 5BO8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WNB A;  5BO6 A;  5BO9 A;  2WNF A;  5BO7 A;  2WML A;  5CXY A;  4JS1 A;  4JS2 A;  4MPS A;  5BO8 A; 
#chains in the Genus database with same CATH topology
 2WML A;  2WQQ A;  2X63 A;  2X61 A;  2P2V A;  2P56 A;  2WNB A;  1RO7 A;  5BO9 A;  2WNF A;  5BO7 A;  5BO8 A;  2X62 A;  4MPS A;  2DRJ A;  4JS2 A;  5BO6 A;  5CXY A;  4JS1 A;  1RO8 A; 
#chains in the Genus database with same CATH homology
 2WNB A;  5BO6 A;  5BO9 A;  2WNF A;  5BO7 A;  2WML A;  5CXY A;  4JS1 A;  4JS2 A;  4MPS A;  5BO8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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