2WNFA

Crystal structure of a mammalian sialyltransferase in complex with gal-beta-1-3galnac-ortho-nitrophenol
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
283
structure length
272
Chain Sequence
PCTCTRCIEEQRVSAWFDERFNRSMQPLLTAKNAHLEEDTYKWWLRLQREKQPNNLNDTIRELFQVVPGNVDPLLEKRLVSCRRCAVVGNSGNLKESYYGPQIDSHDFVLRMNKAPTEGFEADVGSKTTHHFVYPESFRELAQEVSMILVPFKTTDLEWVISATTTGRISHTYVPVPAKIKVKKEKILIYHPAFIKYVFDRWLQGHGRYPSTGILSVIFSLHICDEVDLYGFGADSKGNWHHYWEGVHDGDFESNVTTILASINKIRIFKGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insight Into Mammalian Sialyltransferases.
pubmed doi rcsb
molecule tags Transferase
source organism Sus scrofa
molecule keywords CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLT
total genus 96
structure length 272
sequence length 283
ec nomenclature ec 2.4.99.4: Beta-galactoside alpha-2,3-sialyltransferase.
pdb deposition date 2009-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00777 Glyco_transf_29 Glycosyltransferase family 29 (sialyltransferase)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1480.20 Alpha Beta Alpha-Beta Complex sialyltransferase cstii, chain A sialyltransferase cstii, chain A 2wnfA00
2WNBA 4MPSA 4JS1A 5BO6A 5BO9A 2WNFA 4JS2A 2WMLA 5BO8A 5CXYA 5BO7A
chains in the Genus database with same CATH superfamily
2X61A 2X62A 4JS1A 4JS2A 2P2VA 2WMLA 1RO8A 2DRJA 2X63A 2P56A 5BO6A 2WQQA 5BO9A 5CXYA 1RO7A 2WNBA 4MPSA 2WNFA 5BO8A 5BO7A
chains in the Genus database with same CATH topology
2WNBA 4MPSA 4JS1A 5BO6A 5BO9A 2WNFA 4JS2A 2WMLA 5BO8A 5CXYA 5BO7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WNB A;  4MPS A;  4JS1 A;  5BO6 A;  5BO9 A;  2WNF A;  4JS2 A;  2WML A;  5BO8 A;  5CXY A;  5BO7 A; 
#chains in the Genus database with same CATH topology
 2X61 A;  2X62 A;  4JS1 A;  4JS2 A;  2P2V A;  2WML A;  1RO8 A;  2DRJ A;  2X63 A;  2P56 A;  5BO6 A;  2WQQ A;  5BO9 A;  5CXY A;  1RO7 A;  2WNB A;  4MPS A;  2WNF A;  5BO8 A;  5BO7 A; 
#chains in the Genus database with same CATH homology
 2WNB A;  4MPS A;  4JS1 A;  5BO6 A;  5BO9 A;  2WNF A;  4JS2 A;  2WML A;  5BO8 A;  5CXY A;  5BO7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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