2XMIA

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, complexed with citrate
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
219
structure length
216
Chain Sequence
LEKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Myelin 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase: Active-Site Ligand Binding and Molecular Conformation.
pubmed doi rcsb
molecule keywords 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE
molecule tags Hydrolase
source organism Mus musculus
total genus 53
structure length 216
sequence length 219
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2010-07-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 2xmiA00
2YOZA 2YQ9A 4WDBA 4WDGA 3ZBSA 4WCCA 4WEXA 4WBLA 4WBIA 2Y1PA 1WOJA 2XMIA 4WDDA 4WCAA 2YP0A 4WFRA 2YPEA 4WC9A 4WDEA 4WDHA 2YDDA 2YDCA 3ZBZA 3ZBRA 4WDFA 4WCBA 4WDAA 5AE0A 2YDBA 2YPCA 2ILXA 2YPHA 2I3EA 2Y3XA
chains in the Genus database with same CATH superfamily
2YOZA 2YQ9A 4WDBA 4WDGA 3ZBSA 4WCCA 4WEXA 4WBLA 4WBIA 2Y1PA 1WOJA 2XMIA 4WDDA 4WCAA 2YP0A 4WFRA 2YPEA 4WC9A 4WDEA 4WDHA 2YDDA 2YDCA 3ZBZA 3ZBRA 4WDFA 4WCBA 4WDAA 5AE0A 2YDBA 2YPCA 2ILXA 2YPHA 2I3EA 2Y3XA
chains in the Genus database with same CATH topology
2YOZA 2YQ9A 4WDBA 4WDGA 3ZBSA 4WCCA 4WEXA 4WBLA 4WBIA 2Y1PA 1WOJA 2XMIA 4WDDA 4WCAA 2YP0A 4WFRA 2YPEA 4WC9A 4WDEA 4WDHA 2YDDA 2YDCA 3ZBZA 3ZBRA 4WDFA 4WCBA 4WDAA 5AE0A 2YDBA 2YPCA 2ILXA 2YPHA 2I3EA 2Y3XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YOZ A;  2YQ9 A;  4WDB A;  4WDG A;  3ZBS A;  4WCC A;  4WEX A;  4WBL A;  4WBI A;  2Y1P A;  1WOJ A;  2XMI A;  4WDD A;  4WCA A;  2YP0 A;  4WFR A;  2YPE A;  4WC9 A;  4WDE A;  4WDH A;  2YDD A;  2YDC A;  3ZBZ A;  3ZBR A;  4WDF A;  4WCB A;  4WDA A;  5AE0 A;  2YDB A;  2YPC A;  2ILX A;  2YPH A;  2I3E A;  2Y3X A; 
#chains in the Genus database with same CATH topology
 2YOZ A;  2YQ9 A;  4WDB A;  4WDG A;  3ZBS A;  4WCC A;  4WEX A;  4WBL A;  4WBI A;  2Y1P A;  1WOJ A;  2XMI A;  4WDD A;  4WCA A;  2YP0 A;  4WFR A;  2YPE A;  4WC9 A;  4WDE A;  4WDH A;  2YDD A;  2YDC A;  3ZBZ A;  3ZBR A;  4WDF A;  4WCB A;  4WDA A;  5AE0 A;  2YDB A;  2YPC A;  2ILX A;  2YPH A;  2I3E A;  2Y3X A; 
#chains in the Genus database with same CATH homology
 2YOZ A;  2YQ9 A;  4WDB A;  4WDG A;  3ZBS A;  4WCC A;  4WEX A;  4WBL A;  4WBI A;  2Y1P A;  1WOJ A;  2XMI A;  4WDD A;  4WCA A;  2YP0 A;  4WFR A;  2YPE A;  4WC9 A;  4WDE A;  4WDH A;  2YDD A;  2YDC A;  3ZBZ A;  3ZBR A;  4WDF A;  4WCB A;  4WDA A;  5AE0 A;  2YDB A;  2YPC A;  2ILX A;  2YPH A;  2I3E A;  2Y3X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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