2XMNA

High resolution snapshots of defined tolc open states present an iris- like movement of periplasmic entrance helices
Total Genus 156
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
156
sequence length
428
structure length
428
Chain Sequence
ENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSKWRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNARAQYDTVLANELTARNNLDNAVEQLRQITGNYYPELAALNVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTASTGISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGFSVGTSTIVDVLDATTTLYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of sequential open states in a symmetrical opening transition of the TolC exit duct.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli (strain k12)
molecule keywords Outer membrane protein TolC
total genus 156
structure length 428
sequence length 428
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2010-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02321 OEP Outer membrane efflux protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1600.10 Mainly Alpha Up-down Bundle Outer membrane efflux proteins (OEP) Outer membrane efflux proteins (OEP) 2xmnA00
5IUYA 4K7RA 3PIKA 4K7KA 3D5KA 1EK9A 5BUNA 2WMZA 1YC9A 1WP1A 4Y1KA 2XMNA 1TQQA 5AZOA 4K34A 2VDDA 2VDEA 5AZSA 5AZPA 4MT4A 4MT0A
chains in the Genus database with same CATH superfamily
5IUYA 4K7RA 3PIKA 4K7KA 3D5KA 1EK9A 5BUNA 2WMZA 1YC9A 1WP1A 4Y1KA 2XMNA 1TQQA 5AZOA 4K34A 2VDDA 2VDEA 5AZSA 5AZPA 4MT4A 4MT0A
chains in the Genus database with same CATH topology
5IUYA 4K7RA 3PIKA 4K7KA 3D5KA 1EK9A 5BUNA 2WMZA 1YC9A 1WP1A 4Y1KA 2XMNA 1TQQA 5AZOA 4K34A 2VDDA 2VDEA 5AZSA 5AZPA 4MT4A 4MT0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IUY A;  4K7R A;  3PIK A;  4K7K A;  3D5K A;  1EK9 A;  5BUN A;  2WMZ A;  1YC9 A;  1WP1 A;  4Y1K A;  2XMN A;  1TQQ A;  5AZO A;  4K34 A;  2VDD A;  2VDE A;  5AZS A;  5AZP A;  4MT4 A;  4MT0 A; 
#chains in the Genus database with same CATH topology
 5IUY A;  4K7R A;  3PIK A;  4K7K A;  3D5K A;  1EK9 A;  5BUN A;  2WMZ A;  1YC9 A;  1WP1 A;  4Y1K A;  2XMN A;  1TQQ A;  5AZO A;  4K34 A;  2VDD A;  2VDE A;  5AZS A;  5AZP A;  4MT4 A;  4MT0 A; 
#chains in the Genus database with same CATH homology
 5IUY A;  4K7R A;  3PIK A;  4K7K A;  3D5K A;  1EK9 A;  5BUN A;  2WMZ A;  1YC9 A;  1WP1 A;  4Y1K A;  2XMN A;  1TQQ A;  5AZO A;  4K34 A;  2VDD A;  2VDE A;  5AZS A;  5AZP A;  4MT4 A;  4MT0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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