2Y1PA

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, complexed with citrate
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
218
structure length
218
Chain Sequence
EKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEPKEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Myelin 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase: Active-Site Ligand Binding and Molecular Conformation.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mus musculus
molecule keywords 2', 3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE
total genus 50
structure length 218
sequence length 218
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2010-12-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 2y1pA00
4WDDA 4WFRA 2Y1PA 2Y3XA 4WDFA 2YDCA 2YPEA 5AE0A 3ZBSA 4WDGA 2XMIA 4WEXA 2YPHA 4WBIA 4WDAA 1WOJA 4WBLA 2ILXA 3ZBZA 2YDDA 4WCBA 4WDHA 2YDBA 2YQ9A 4WCAA 3ZBRA 4WDEA 4WDBA 4WCCA 2YOZA 2YPCA 2YP0A 4WC9A 2I3EA
chains in the Genus database with same CATH superfamily
4WDDA 4WFRA 2Y1PA 2Y3XA 4WDFA 2YDCA 2YPEA 5AE0A 3ZBSA 4WDGA 2XMIA 4WEXA 2YPHA 4WBIA 4WDAA 1WOJA 4WBLA 2ILXA 3ZBZA 2YDDA 4WCBA 4WDHA 2YDBA 2YQ9A 4WCAA 3ZBRA 4WDEA 4WDBA 4WCCA 2YOZA 2YPCA 2YP0A 4WC9A 2I3EA
chains in the Genus database with same CATH topology
4WDDA 4WFRA 2Y1PA 2Y3XA 4WDFA 2YDCA 2YPEA 5AE0A 3ZBSA 4WDGA 2XMIA 4WEXA 2YPHA 4WBIA 4WDAA 1WOJA 4WBLA 2ILXA 3ZBZA 2YDDA 4WCBA 4WDHA 2YDBA 2YQ9A 4WCAA 3ZBRA 4WDEA 4WDBA 4WCCA 2YOZA 2YPCA 2YP0A 4WC9A 2I3EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WDD A;  4WFR A;  2Y1P A;  2Y3X A;  4WDF A;  2YDC A;  2YPE A;  5AE0 A;  3ZBS A;  4WDG A;  2XMI A;  4WEX A;  2YPH A;  4WBI A;  4WDA A;  1WOJ A;  4WBL A;  2ILX A;  3ZBZ A;  2YDD A;  4WCB A;  4WDH A;  2YDB A;  2YQ9 A;  4WCA A;  3ZBR A;  4WDE A;  4WDB A;  4WCC A;  2YOZ A;  2YPC A;  2YP0 A;  4WC9 A;  2I3E A; 
#chains in the Genus database with same CATH topology
 4WDD A;  4WFR A;  2Y1P A;  2Y3X A;  4WDF A;  2YDC A;  2YPE A;  5AE0 A;  3ZBS A;  4WDG A;  2XMI A;  4WEX A;  2YPH A;  4WBI A;  4WDA A;  1WOJ A;  4WBL A;  2ILX A;  3ZBZ A;  2YDD A;  4WCB A;  4WDH A;  2YDB A;  2YQ9 A;  4WCA A;  3ZBR A;  4WDE A;  4WDB A;  4WCC A;  2YOZ A;  2YPC A;  2YP0 A;  4WC9 A;  2I3E A; 
#chains in the Genus database with same CATH homology
 4WDD A;  4WFR A;  2Y1P A;  2Y3X A;  4WDF A;  2YDC A;  2YPE A;  5AE0 A;  3ZBS A;  4WDG A;  2XMI A;  4WEX A;  2YPH A;  4WBI A;  4WDA A;  1WOJ A;  4WBL A;  2ILX A;  3ZBZ A;  2YDD A;  4WCB A;  4WDH A;  2YDB A;  2YQ9 A;  4WCA A;  3ZBR A;  4WDE A;  4WDB A;  4WCC A;  2YOZ A;  2YPC A;  2YP0 A;  4WC9 A;  2I3E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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