2Y1SA

Microvirin lectin
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
108
structure length
108
Chain Sequence
MPNFSHTCSSINYDPDSTILSAECQARDGEWLPTELRLSDHIGNIDGELQFGDQNFQETCQDCRLEFGDGEQSVWLVCTCQTMDGEWKSTQILLDSQIDNNDSQLEIG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Microcystis aeruginosa
molecule keywords Mannan-binding lectin
total genus 16
structure length 108
sequence length 108
ec nomenclature
pdb deposition date 2010-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08881 CVNH CVNH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.60.10 Mainly Beta Roll HIV-inactivating Protein, Cyanovirin-n Cyanovirin-N 2y1sA00
3GXZA 3S3YA 1IIYA 1L5EA 3S3ZA 2EZMA 2L2FA 1L5BA 3EZMA 2JZKA 5C8QB 3GXYA 1J4VA 2JZJA 1N02A 2PYSA 5C8OA 1LOMA 4J4EA 4J4FA 2Z21A 5C8PA 2RP3A 2RDKA 3HNXA 2JZLA 2EZNA 2YHHA 3CZZA 2L9YA 3HP8A 3LHCA 4J4CA 3HNUX 2Y1SA 2KJLA
chains in the Genus database with same CATH superfamily
3GXZA 3S3YA 1IIYA 1L5EA 3S3ZA 2EZMA 2L2FA 1L5BA 3EZMA 2JZKA 5C8QB 3GXYA 1J4VA 2JZJA 1N02A 2PYSA 5C8OA 1LOMA 4J4EA 4J4FA 2Z21A 5C8PA 2RP3A 2RDKA 3HNXA 2JZLA 2EZNA 2YHHA 3CZZA 2L9YA 3HP8A 3LHCA 4J4CA 3HNUX 2Y1SA 2KJLA
chains in the Genus database with same CATH topology
3GXZA 3S3YA 1IIYA 1L5EA 3S3ZA 2EZMA 2L2FA 1L5BA 3EZMA 2JZKA 5C8QB 3GXYA 1J4VA 2JZJA 1N02A 2PYSA 5C8OA 1LOMA 4J4EA 4J4FA 2Z21A 5C8PA 2RP3A 2RDKA 3HNXA 2JZLA 2EZNA 2YHHA 3CZZA 2L9YA 3HP8A 3LHCA 4J4CA 3HNUX 2Y1SA 2KJLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GXZ A;  3S3Y A;  1IIY A;  1L5E A;  3S3Z A;  2EZM A;  2L2F A;  1L5B A;  3EZM A;  2JZK A;  5C8Q B;  3GXY A;  1J4V A;  2JZJ A;  1N02 A;  2PYS A;  5C8O A;  1LOM A;  4J4E A;  4J4F A;  2Z21 A;  5C8P A;  2RP3 A;  2RDK A;  3HNX A;  2JZL A;  2EZN A;  2YHH A;  3CZZ A;  2L9Y A;  3HP8 A;  3LHC A;  4J4C A;  3HNU X;  2Y1S A;  2KJL A; 
#chains in the Genus database with same CATH topology
 3GXZ A;  3S3Y A;  1IIY A;  1L5E A;  3S3Z A;  2EZM A;  2L2F A;  1L5B A;  3EZM A;  2JZK A;  5C8Q B;  3GXY A;  1J4V A;  2JZJ A;  1N02 A;  2PYS A;  5C8O A;  1LOM A;  4J4E A;  4J4F A;  2Z21 A;  5C8P A;  2RP3 A;  2RDK A;  3HNX A;  2JZL A;  2EZN A;  2YHH A;  3CZZ A;  2L9Y A;  3HP8 A;  3LHC A;  4J4C A;  3HNU X;  2Y1S A;  2KJL A; 
#chains in the Genus database with same CATH homology
 3GXZ A;  3S3Y A;  1IIY A;  1L5E A;  3S3Z A;  2EZM A;  2L2F A;  1L5B A;  3EZM A;  2JZK A;  5C8Q B;  3GXY A;  1J4V A;  2JZJ A;  1N02 A;  2PYS A;  5C8O A;  1LOM A;  4J4E A;  4J4F A;  2Z21 A;  5C8P A;  2RP3 A;  2RDK A;  3HNX A;  2JZL A;  2EZN A;  2YHH A;  3CZZ A;  2L9Y A;  3HP8 A;  3LHC A;  4J4C A;  3HNU X;  2Y1S A;  2KJL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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