2Y1SA

Microvirin lectin
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
108
structure length
108
Chain Sequence
MPNFSHTCSSINYDPDSTILSAECQARDGEWLPTELRLSDHIGNIDGELQFGDQNFQETCQDCRLEFGDGEQSVWLVCTCQTMDGEWKSTQILLDSQIDNNDSQLEIG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Microcystis aeruginosa
molecule keywords Mannan-binding lectin
total genus 16
structure length 108
sequence length 108
ec nomenclature
pdb deposition date 2010-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08881 CVNH CVNH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.60.10 Mainly Beta Roll HIV-inactivating Protein, Cyanovirin-n Cyanovirin-N 2y1sA00
2Y1SA 2L9YA 2EZMA 3HP8A 3HNXA 5C8QB 2Z21A 5C8OA 3EZMA 3CZZA 4J4CA 2RP3A 1L5EA 2JZJA 2EZNA 2PYSA 2YHHA 4J4EA 2RDKA 1L5BA 1J4VA 1IIYA 3S3ZA 1LOMA 2KJLA 3GXYA 5C8PA 3LHCA 3HNUX 1N02A 4J4FA 2L2FA 3S3YA 2JZKA 2JZLA 3GXZA
chains in the Genus database with same CATH superfamily
2Y1SA 2L9YA 2EZMA 3HP8A 3HNXA 5C8QB 2Z21A 5C8OA 3EZMA 3CZZA 4J4CA 2RP3A 1L5EA 2JZJA 2EZNA 2PYSA 2YHHA 4J4EA 2RDKA 1L5BA 1J4VA 1IIYA 3S3ZA 1LOMA 2KJLA 3GXYA 5C8PA 3LHCA 3HNUX 1N02A 4J4FA 2L2FA 3S3YA 2JZKA 2JZLA 3GXZA
chains in the Genus database with same CATH topology
2Y1SA 2L9YA 2EZMA 3HP8A 3HNXA 5C8QB 2Z21A 5C8OA 3EZMA 3CZZA 4J4CA 2RP3A 1L5EA 2JZJA 2EZNA 2PYSA 2YHHA 4J4EA 2RDKA 1L5BA 1J4VA 1IIYA 3S3ZA 1LOMA 2KJLA 3GXYA 5C8PA 3LHCA 3HNUX 1N02A 4J4FA 2L2FA 3S3YA 2JZKA 2JZLA 3GXZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y1S A;  2L9Y A;  2EZM A;  3HP8 A;  3HNX A;  5C8Q B;  2Z21 A;  5C8O A;  3EZM A;  3CZZ A;  4J4C A;  2RP3 A;  1L5E A;  2JZJ A;  2EZN A;  2PYS A;  2YHH A;  4J4E A;  2RDK A;  1L5B A;  1J4V A;  1IIY A;  3S3Z A;  1LOM A;  2KJL A;  3GXY A;  5C8P A;  3LHC A;  3HNU X;  1N02 A;  4J4F A;  2L2F A;  3S3Y A;  2JZK A;  2JZL A;  3GXZ A; 
#chains in the Genus database with same CATH topology
 2Y1S A;  2L9Y A;  2EZM A;  3HP8 A;  3HNX A;  5C8Q B;  2Z21 A;  5C8O A;  3EZM A;  3CZZ A;  4J4C A;  2RP3 A;  1L5E A;  2JZJ A;  2EZN A;  2PYS A;  2YHH A;  4J4E A;  2RDK A;  1L5B A;  1J4V A;  1IIY A;  3S3Z A;  1LOM A;  2KJL A;  3GXY A;  5C8P A;  3LHC A;  3HNU X;  1N02 A;  4J4F A;  2L2F A;  3S3Y A;  2JZK A;  2JZL A;  3GXZ A; 
#chains in the Genus database with same CATH homology
 2Y1S A;  2L9Y A;  2EZM A;  3HP8 A;  3HNX A;  5C8Q B;  2Z21 A;  5C8O A;  3EZM A;  3CZZ A;  4J4C A;  2RP3 A;  1L5E A;  2JZJ A;  2EZN A;  2PYS A;  2YHH A;  4J4E A;  2RDK A;  1L5B A;  1J4V A;  1IIY A;  3S3Z A;  1LOM A;  2KJL A;  3GXY A;  5C8P A;  3LHC A;  3HNU X;  1N02 A;  4J4F A;  2L2F A;  3S3Y A;  2JZK A;  2JZL A;  3GXZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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