2YPEA

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation h309s, crystallized with 2',3'- cyclic amp
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
217
structure length
214
Chain Sequence
KDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEPKEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRASVTLGCAADVQPVQTGLDLLDILQQVKQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
pubmed doi rcsb
molecule keywords 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE
molecule tags Hydrolase
source organism Mus musculus
total genus 49
structure length 214
sequence length 217
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2012-10-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 2ypeA00
4WDAA 2YDBA 2YPEA 4WCAA 2YPCA 4WDDA 4WDBA 2YDCA 2ILXA 2YQ9A 1WOJA 2XMIA 4WC9A 4WBIA 4WBLA 4WDGA 4WFRA 4WEXA 4WCBA 3ZBRA 2YDDA 2Y1PA 4WDFA 3ZBSA 2Y3XA 2I3EA 2YOZA 2YPHA 4WDEA 2YP0A 5AE0A 3ZBZA 4WDHA 4WCCA
chains in the Genus database with same CATH superfamily
4WDAA 2YDBA 2YPEA 4WCAA 2YPCA 4WDDA 4WDBA 2YDCA 2ILXA 2YQ9A 1WOJA 2XMIA 4WC9A 4WBIA 4WBLA 4WDGA 4WFRA 4WEXA 4WCBA 3ZBRA 2YDDA 2Y1PA 4WDFA 3ZBSA 2Y3XA 2I3EA 2YOZA 2YPHA 4WDEA 2YP0A 5AE0A 3ZBZA 4WDHA 4WCCA
chains in the Genus database with same CATH topology
4WDAA 2YDBA 2YPEA 4WCAA 2YPCA 4WDDA 4WDBA 2YDCA 2ILXA 2YQ9A 1WOJA 2XMIA 4WC9A 4WBIA 4WBLA 4WDGA 4WFRA 4WEXA 4WCBA 3ZBRA 2YDDA 2Y1PA 4WDFA 3ZBSA 2Y3XA 2I3EA 2YOZA 2YPHA 4WDEA 2YP0A 5AE0A 3ZBZA 4WDHA 4WCCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WDA A;  2YDB A;  2YPE A;  4WCA A;  2YPC A;  4WDD A;  4WDB A;  2YDC A;  2ILX A;  2YQ9 A;  1WOJ A;  2XMI A;  4WC9 A;  4WBI A;  4WBL A;  4WDG A;  4WFR A;  4WEX A;  4WCB A;  3ZBR A;  2YDD A;  2Y1P A;  4WDF A;  3ZBS A;  2Y3X A;  2I3E A;  2YOZ A;  2YPH A;  4WDE A;  2YP0 A;  5AE0 A;  3ZBZ A;  4WDH A;  4WCC A; 
#chains in the Genus database with same CATH topology
 4WDA A;  2YDB A;  2YPE A;  4WCA A;  2YPC A;  4WDD A;  4WDB A;  2YDC A;  2ILX A;  2YQ9 A;  1WOJ A;  2XMI A;  4WC9 A;  4WBI A;  4WBL A;  4WDG A;  4WFR A;  4WEX A;  4WCB A;  3ZBR A;  2YDD A;  2Y1P A;  4WDF A;  3ZBS A;  2Y3X A;  2I3E A;  2YOZ A;  2YPH A;  4WDE A;  2YP0 A;  5AE0 A;  3ZBZ A;  4WDH A;  4WCC A; 
#chains in the Genus database with same CATH homology
 4WDA A;  2YDB A;  2YPE A;  4WCA A;  2YPC A;  4WDD A;  4WDB A;  2YDC A;  2ILX A;  2YQ9 A;  1WOJ A;  2XMI A;  4WC9 A;  4WBI A;  4WBL A;  4WDG A;  4WFR A;  4WEX A;  4WCB A;  3ZBR A;  2YDD A;  2Y1P A;  4WDF A;  3ZBS A;  2Y3X A;  2I3E A;  2YOZ A;  2YPH A;  4WDE A;  2YP0 A;  5AE0 A;  3ZBZ A;  4WDH A;  4WCC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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