2ZPB | Genus

Total Genus 60

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	60
sequence length	197
structure length	195
Chain Sequence	ENAAPAQAPVSDRAWALFRALDGKGLVPDGYVEGWKKTFEEDFSPRRGAELVARAWTDPEFRQLLLTDGTAAVAQYGYLGPQGEYIVAVEDTPTLKNVIVCSLSTAWPILGLPPTWYKSFEYRARVVREPRKVLSEMGTEIASDIEIRVYDTTAETRYMVLPQRPAGTEGWSQEQLQEIVTKDCLIGVAIPQVPT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 195 atoms

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195 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase
publication title	Catalytic mechanism of nitrile hydratase proposed by time-resolved X-ray crystallography using a novel substrate, tert-butylisonitrile pubmed doi rcsb
molecule keywords	Nitrile hydratase subunit alpha
total genus	60
structure length	195
sequence length	197
ec nomenclature	ec 4.2.1.84: Nitrile hydratase.
pdb deposition date	2008-07-09

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02979	NHase_alpha	Nitrile hydratase, alpha chain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.330.10	Alpha Beta	Alpha-Beta Complex	Nitrile Hydratase; Chain A	Nitrile hydratase alpha /Thiocyanate hydrolase gamma	2zpbA00

3A8MA 2ZPGA 2ZPIA 2CZ6A 2ZZDC 2DD4C 2DXCC 4ZGDA 2CZ1A 3WVDA 2DPPA 2ZPHA 3X26A 4OB1A 2CZ7A 3WVEA 3A8LA 2DD5C 3HHTA 1UGPA 2ZPFA 1UGQA 3QYGA 4ZGJA 2ZPEA 3A8GA 3QYHA 3VYGC 3A8HA 3X20A 4ZGEA 2CYZA 1UGSA 2QDYA 3X24A 2CZ0A 3QXEA 4OB3A 2AHJA 2DXBC 1AHJA 3QZ9A 2D0QA 2ZPBA 4OB2A 3VYHA 3X25A 1IREA 3X28A 1UGRA 4OB0A 1V29A 4FM4A 3A8OA 2ZCFA 3QZ5A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3A8M A;  2ZPG A;  2ZPI A;  2CZ6 A;  2ZZD C;  2DD4 C;  2DXC C;  4ZGD A;  2CZ1 A;  3WVD A;  2DPP A;  2ZPH A;  3X26 A;  4OB1 A;  2CZ7 A;  3WVE A;  3A8L A;  2DD5 C;  3HHT A;  1UGP A;  2ZPF A;  1UGQ A;  3QYG A;  4ZGJ A;  2ZPE A;  3A8G A;  3QYH A;  3VYG C;  3A8H A;  3X20 A;  4ZGE A;  2CYZ A;  1UGS A;  2QDY A;  3X24 A;  2CZ0 A;  3QXE A;  4OB3 A;  2AHJ A;  2DXB C;  1AHJ A;  3QZ9 A;  2D0Q A;  2ZPB A;  4OB2 A;  3VYH A;  3X25 A;  1IRE A;  3X28 A;  1UGR A;  4OB0 A;  1V29 A;  4FM4 A;  3A8O A;  2ZCF A;  3QZ5 A; 
#chains in the Genus database with same CATH topology
 3A8M A;  2ZPG A;  2ZPI A;  2CZ6 A;  2ZZD C;  2DD4 C;  2DXC C;  4ZGD A;  2CZ1 A;  3WVD A;  2DPP A;  2ZPH A;  3X26 A;  4OB1 A;  2CZ7 A;  3WVE A;  3A8L A;  2DD5 C;  3HHT A;  1UGP A;  2ZPF A;  1UGQ A;  3QYG A;  4ZGJ A;  2ZPE A;  3A8G A;  3QYH A;  3VYG C;  3A8H A;  3X20 A;  4ZGE A;  2CYZ A;  1UGS A;  2QDY A;  3X24 A;  2CZ0 A;  3QXE A;  4OB3 A;  2AHJ A;  2DXB C;  1AHJ A;  3QZ9 A;  2D0Q A;  2ZPB A;  4OB2 A;  3VYH A;  3X25 A;  1IRE A;  3X28 A;  1UGR A;  4OB0 A;  1V29 A;  4FM4 A;  3A8O A;  2ZCF A;  3QZ5 A; 
#chains in the Genus database with same CATH homology
 3A8M A;  2ZPG A;  2ZPI A;  2CZ6 A;  2ZZD C;  2DD4 C;  2DXC C;  4ZGD A;  2CZ1 A;  3WVD A;  2DPP A;  2ZPH A;  3X26 A;  4OB1 A;  2CZ7 A;  3WVE A;  3A8L A;  2DD5 C;  3HHT A;  1UGP A;  2ZPF A;  1UGQ A;  3QYG A;  4ZGJ A;  2ZPE A;  3A8G A;  3QYH A;  3VYG C;  3A8H A;  3X20 A;  4ZGE A;  2CYZ A;  1UGS A;  2QDY A;  3X24 A;  2CZ0 A;  3QXE A;  4OB3 A;  2AHJ A;  2DXB C;  1AHJ A;  3QZ9 A;  2D0Q A;  2ZPB A;  4OB2 A;  3VYH A;  3X25 A;  1IRE A;  3X28 A;  1UGR A;  4OB0 A;  1V29 A;  4FM4 A;  3A8O A;  2ZCF A;  3QZ5 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2ZPBA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations