2ZPE | Genus

Total Genus 60

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	60
sequence length	196
structure length	194
Chain Sequence	ENAAPAQAPVSDRAWALFRALDGKGLVPDGYVEGWKKTFEEDFSPRRGAELVARAWTDPEFRQLLLTDGTAAVAQYGYLGPQGEYIVAVEDTPTLKNVIVCSLSTAWPILGLPPTWYKSFEYRARVVREPRKVLSEMGTEIASDIEIRVYDTTAETRYMVLPQRPAGTEGWSQEQLQEIVTKDCLIGVAIPQVP

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase
publication title	Catalytic mechanism of nitrile hydratase proposed by time-resolved X-ray crystallography using a novel substrate, tert-butylisonitrile pubmed doi rcsb
molecule keywords	Nitrile hydratase subunit alpha
total genus	60
structure length	194
sequence length	196
ec nomenclature	ec 4.2.1.84: Nitrile hydratase.
pdb deposition date	2008-07-10

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02979	NHase_alpha	Nitrile hydratase, alpha chain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.330.10	Alpha Beta	Alpha-Beta Complex	Nitrile Hydratase; Chain A	Nitrile hydratase alpha /Thiocyanate hydrolase gamma	2zpeA00

3VYGC 3X25A 4OB2A 4FM4A 4OB1A 3QZ5A 1UGQA 2ZPIA 2ZCFA 1V29A 1IREA 2CZ6A 2CYZA 2CZ0A 3X24A 2DD4C 2ZPBA 2D0QA 3A8OA 4ZGJA 2DD5C 3WVEA 2ZPFA 3A8LA 3A8HA 2DPPA 1UGRA 2ZPEA 3QYHA 2ZPGA 2DXCC 2ZZDC 4ZGDA 3HHTA 3X26A 3VYHA 1UGPA 2CZ7A 3QZ9A 4OB3A 3WVDA 3QXEA 2AHJA 3QYGA 3A8GA 4OB0A 3X20A 3A8MA 2DXBC 2QDYA 1AHJA 4ZGEA 2CZ1A 1UGSA 3X28A 2ZPHA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3VYG C;  3X25 A;  4OB2 A;  4FM4 A;  4OB1 A;  3QZ5 A;  1UGQ A;  2ZPI A;  2ZCF A;  1V29 A;  1IRE A;  2CZ6 A;  2CYZ A;  2CZ0 A;  3X24 A;  2DD4 C;  2ZPB A;  2D0Q A;  3A8O A;  4ZGJ A;  2DD5 C;  3WVE A;  2ZPF A;  3A8L A;  3A8H A;  2DPP A;  1UGR A;  2ZPE A;  3QYH A;  2ZPG A;  2DXC C;  2ZZD C;  4ZGD A;  3HHT A;  3X26 A;  3VYH A;  1UGP A;  2CZ7 A;  3QZ9 A;  4OB3 A;  3WVD A;  3QXE A;  2AHJ A;  3QYG A;  3A8G A;  4OB0 A;  3X20 A;  3A8M A;  2DXB C;  2QDY A;  1AHJ A;  4ZGE A;  2CZ1 A;  1UGS A;  3X28 A;  2ZPH A; 
#chains in the Genus database with same CATH topology
 3VYG C;  3X25 A;  4OB2 A;  4FM4 A;  4OB1 A;  3QZ5 A;  1UGQ A;  2ZPI A;  2ZCF A;  1V29 A;  1IRE A;  2CZ6 A;  2CYZ A;  2CZ0 A;  3X24 A;  2DD4 C;  2ZPB A;  2D0Q A;  3A8O A;  4ZGJ A;  2DD5 C;  3WVE A;  2ZPF A;  3A8L A;  3A8H A;  2DPP A;  1UGR A;  2ZPE A;  3QYH A;  2ZPG A;  2DXC C;  2ZZD C;  4ZGD A;  3HHT A;  3X26 A;  3VYH A;  1UGP A;  2CZ7 A;  3QZ9 A;  4OB3 A;  3WVD A;  3QXE A;  2AHJ A;  3QYG A;  3A8G A;  4OB0 A;  3X20 A;  3A8M A;  2DXB C;  2QDY A;  1AHJ A;  4ZGE A;  2CZ1 A;  1UGS A;  3X28 A;  2ZPH A; 
#chains in the Genus database with same CATH homology
 3VYG C;  3X25 A;  4OB2 A;  4FM4 A;  4OB1 A;  3QZ5 A;  1UGQ A;  2ZPI A;  2ZCF A;  1V29 A;  1IRE A;  2CZ6 A;  2CYZ A;  2CZ0 A;  3X24 A;  2DD4 C;  2ZPB A;  2D0Q A;  3A8O A;  4ZGJ A;  2DD5 C;  3WVE A;  2ZPF A;  3A8L A;  3A8H A;  2DPP A;  1UGR A;  2ZPE A;  3QYH A;  2ZPG A;  2DXC C;  2ZZD C;  4ZGD A;  3HHT A;  3X26 A;  3VYH A;  1UGP A;  2CZ7 A;  3QZ9 A;  4OB3 A;  3WVD A;  3QXE A;  2AHJ A;  3QYG A;  3A8G A;  4OB0 A;  3X20 A;  3A8M A;  2DXB C;  2QDY A;  1AHJ A;  4ZGE A;  2CZ1 A;  1UGS A;  3X28 A;  2ZPH A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2ZPEA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations