2ZPHA

Complex of fe-type nitrile hydratase with tert-butylisonitrile, photo-activated for 340min at 293k
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
191
structure length
189
Chain Sequence
AQAPVSDRAWALFRALDGKGLVPDGYVEGWKKTFEEDFSPRRGAELVARAWTDPEFRQLLLTDGTAAVAQYGYLGPQGEYIVAVEDTPTLKNVIVCSLSTAWPILGLPPTWYKSFEYRARVVREPRKVLSEMGTEIASDIEIRVYDTTAETRYMVLPQRPAGTEGWSQEQLQEIVTKDCLIGVAIPQVP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Catalytic mechanism of nitrile hydratase proposed by time-resolved X-ray crystallography using a novel substrate, tert-butylisonitrile
pubmed doi rcsb
molecule tags Lyase
molecule keywords Nitrile hydratase subunit alpha
total genus 59
structure length 189
sequence length 191
ec nomenclature ec 4.2.1.84: Nitrile hydratase.
pdb deposition date 2008-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02979 NHase_alpha Nitrile hydratase, alpha chain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.330.10 Alpha Beta Alpha-Beta Complex Nitrile Hydratase; Chain A Nitrile hydratase alpha /Thiocyanate hydrolase gamma 2zphA00
4OB3A 1UGSA 2CZ0A 3VYHA 2CZ7A 3QZ5A 1UGPA 2ZZDC 2ZPGA 3QZ9A 2CZ6A 1UGQA 4FM4A 1UGRA 3WVEA 1IREA 2ZPBA 3QYGA 2ZPEA 4OB1A 3VYGC 3X28A 3X20A 2AHJA 2DXBC 4OB2A 4ZGEA 2DXCC 1V29A 3X25A 2D0QA 3X24A 3A8OA 3QXEA 3A8HA 3X26A 2ZPFA 2DD4C 3A8MA 3HHTA 4OB0A 3WVDA 4ZGJA 2QDYA 2CZ1A 2DD5C 2ZPHA 1AHJA 3A8LA 2DPPA 2ZPIA 3QYHA 4ZGDA 2CYZA 2ZCFA 3A8GA
chains in the Genus database with same CATH superfamily
4OB3A 1UGSA 2CZ0A 3VYHA 2CZ7A 3QZ5A 1UGPA 2ZZDC 2ZPGA 3QZ9A 2CZ6A 1UGQA 4FM4A 1UGRA 3WVEA 1IREA 2ZPBA 3QYGA 2ZPEA 4OB1A 3VYGC 3X28A 3X20A 2AHJA 2DXBC 4OB2A 4ZGEA 2DXCC 1V29A 3X25A 2D0QA 3X24A 3A8OA 3QXEA 3A8HA 3X26A 2ZPFA 2DD4C 3A8MA 3HHTA 4OB0A 3WVDA 4ZGJA 2QDYA 2CZ1A 2DD5C 2ZPHA 1AHJA 3A8LA 2DPPA 2ZPIA 3QYHA 4ZGDA 2CYZA 2ZCFA 3A8GA
chains in the Genus database with same CATH topology
4OB3A 1UGSA 2CZ0A 3VYHA 2CZ7A 3QZ5A 1UGPA 2ZZDC 2ZPGA 3QZ9A 2CZ6A 1UGQA 4FM4A 1UGRA 3WVEA 1IREA 2ZPBA 3QYGA 2ZPEA 4OB1A 3VYGC 3X28A 3X20A 2AHJA 2DXBC 4OB2A 4ZGEA 2DXCC 1V29A 3X25A 2D0QA 3X24A 3A8OA 3QXEA 3A8HA 3X26A 2ZPFA 2DD4C 3A8MA 3HHTA 4OB0A 3WVDA 4ZGJA 2QDYA 2CZ1A 2DD5C 2ZPHA 1AHJA 3A8LA 2DPPA 2ZPIA 3QYHA 4ZGDA 2CYZA 2ZCFA 3A8GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OB3 A;  1UGS A;  2CZ0 A;  3VYH A;  2CZ7 A;  3QZ5 A;  1UGP A;  2ZZD C;  2ZPG A;  3QZ9 A;  2CZ6 A;  1UGQ A;  4FM4 A;  1UGR A;  3WVE A;  1IRE A;  2ZPB A;  3QYG A;  2ZPE A;  4OB1 A;  3VYG C;  3X28 A;  3X20 A;  2AHJ A;  2DXB C;  4OB2 A;  4ZGE A;  2DXC C;  1V29 A;  3X25 A;  2D0Q A;  3X24 A;  3A8O A;  3QXE A;  3A8H A;  3X26 A;  2ZPF A;  2DD4 C;  3A8M A;  3HHT A;  4OB0 A;  3WVD A;  4ZGJ A;  2QDY A;  2CZ1 A;  2DD5 C;  2ZPH A;  1AHJ A;  3A8L A;  2DPP A;  2ZPI A;  3QYH A;  4ZGD A;  2CYZ A;  2ZCF A;  3A8G A; 
#chains in the Genus database with same CATH topology
 4OB3 A;  1UGS A;  2CZ0 A;  3VYH A;  2CZ7 A;  3QZ5 A;  1UGP A;  2ZZD C;  2ZPG A;  3QZ9 A;  2CZ6 A;  1UGQ A;  4FM4 A;  1UGR A;  3WVE A;  1IRE A;  2ZPB A;  3QYG A;  2ZPE A;  4OB1 A;  3VYG C;  3X28 A;  3X20 A;  2AHJ A;  2DXB C;  4OB2 A;  4ZGE A;  2DXC C;  1V29 A;  3X25 A;  2D0Q A;  3X24 A;  3A8O A;  3QXE A;  3A8H A;  3X26 A;  2ZPF A;  2DD4 C;  3A8M A;  3HHT A;  4OB0 A;  3WVD A;  4ZGJ A;  2QDY A;  2CZ1 A;  2DD5 C;  2ZPH A;  1AHJ A;  3A8L A;  2DPP A;  2ZPI A;  3QYH A;  4ZGD A;  2CYZ A;  2ZCF A;  3A8G A; 
#chains in the Genus database with same CATH homology
 4OB3 A;  1UGS A;  2CZ0 A;  3VYH A;  2CZ7 A;  3QZ5 A;  1UGP A;  2ZZD C;  2ZPG A;  3QZ9 A;  2CZ6 A;  1UGQ A;  4FM4 A;  1UGR A;  3WVE A;  1IRE A;  2ZPB A;  3QYG A;  2ZPE A;  4OB1 A;  3VYG C;  3X28 A;  3X20 A;  2AHJ A;  2DXB C;  4OB2 A;  4ZGE A;  2DXC C;  1V29 A;  3X25 A;  2D0Q A;  3X24 A;  3A8O A;  3QXE A;  3A8H A;  3X26 A;  2ZPF A;  2DD4 C;  3A8M A;  3HHT A;  4OB0 A;  3WVD A;  4ZGJ A;  2QDY A;  2CZ1 A;  2DD5 C;  2ZPH A;  1AHJ A;  3A8L A;  2DPP A;  2ZPI A;  3QYH A;  4ZGD A;  2CYZ A;  2ZCF A;  3A8G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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