2A5VA

Crystal structure of m. tuberculosis beta carbonic anhydrase, rv3588c, tetrameric form
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
210
structure length
210
Chain Sequence
HHHHHHGPNTNPVAAWKALKEGNERFVAGRPQHPSQSVDHRAGLAAGQKPTAVIFGCADSRVAAEIIFDQGLGDMFVVRTAGHVIDSAVLGSIEYAVTVLNVPLIVVLGHDSCGAVNAALAAINDGTLPGGYVRDVVERVAPSVLLGRRDGLSRVDEFEQRHVHETVAILMARSSAISERIAGGSLAIVGVTYQLDDGRAVLRDHIGNIG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Mechanics of the pH-dependent Activity of beta-Carbonic Anhydrase from Mycobacterium tuberculosis
pubmed doi rcsb
molecule tags Lyase
source organism Mycobacterium tuberculosis
molecule keywords CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRA
total genus 69
structure length 210
sequence length 210
chains with identical sequence B, C, D
ec nomenclature ec 4.2.1.1: Carbonic anhydrase.
pdb deposition date 2005-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00484 Pro_CA Carbonic anhydrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1050.10 Alpha Beta 3-Layer(aba) Sandwich Beta-carbonic Anhydrase; Chain A Carbonic anhydrase 2a5vA00
3VRKA 3E2XA 4ZNZA 3MF3A 1I6PA 1T75A 3UCMA 3TENA 4YF5A 3E31A 5SWCA 3UCOA 4RXYA 4O1KA 3E2AA 3E3IA 3E1WA 2W3QA 3QY1A 5JJ8A 5BQ1A 3E24A 2W3NA 4O1JA 4WAKA 1DDZA 2ESFA 3E2WA 3UCKA 3E3FA 3TEOA 3VQJA 5CXKA 4WAJA 4YF4A 3UCNA 1I6OA 4YF6A 1YM3A 1YLKA 3E3GA 2A8DA 3EYXA 1EKJA 3E28A 2A5VA 3LASA 2A8CA 4WAMA 1G5CA 3E1VA 3UCJA
chains in the Genus database with same CATH superfamily
3VRKA 3E2XA 4ZNZA 3MF3A 1I6PA 1T75A 3UCMA 3TENA 4YF5A 3E31A 5SWCA 3UCOA 4RXYA 4O1KA 3E2AA 3E3IA 3E1WA 2W3QA 3QY1A 5JJ8A 5BQ1A 3E24A 2W3NA 4O1JA 4WAKA 1DDZA 2ESFA 3E2WA 3UCKA 3E3FA 3TEOA 3VQJA 5CXKA 4WAJA 4YF4A 3UCNA 1I6OA 4YF6A 1YM3A 1YLKA 3E3GA 2A8DA 3EYXA 1EKJA 3E28A 2A5VA 3LASA 2A8CA 4WAMA 1G5CA 3E1VA 3UCJA
chains in the Genus database with same CATH topology
3VRKA 3E2XA 4ZNZA 3MF3A 1I6PA 1T75A 3UCMA 3TENA 4YF5A 3E31A 5SWCA 3UCOA 4RXYA 4O1KA 3E2AA 3E3IA 3E1WA 2W3QA 3QY1A 5JJ8A 5BQ1A 3E24A 2W3NA 4O1JA 4WAKA 1DDZA 2ESFA 3E2WA 3UCKA 3E3FA 3TEOA 3VQJA 5CXKA 4WAJA 4YF4A 3UCNA 1I6OA 4YF6A 1YM3A 1YLKA 3E3GA 2A8DA 3EYXA 1EKJA 3E28A 2A5VA 3LASA 2A8CA 4WAMA 1G5CA 3E1VA 3UCJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VRK A;  3E2X A;  4ZNZ A;  3MF3 A;  1I6P A;  1T75 A;  3UCM A;  3TEN A;  4YF5 A;  3E31 A;  5SWC A;  3UCO A;  4RXY A;  4O1K A;  3E2A A;  3E3I A;  3E1W A;  2W3Q A;  3QY1 A;  5JJ8 A;  5BQ1 A;  3E24 A;  2W3N A;  4O1J A;  4WAK A;  1DDZ A;  2ESF A;  3E2W A;  3UCK A;  3E3F A;  3TEO A;  3VQJ A;  5CXK A;  4WAJ A;  4YF4 A;  3UCN A;  1I6O A;  4YF6 A;  1YM3 A;  1YLK A;  3E3G A;  2A8D A;  3EYX A;  1EKJ A;  3E28 A;  2A5V A;  3LAS A;  2A8C A;  4WAM A;  1G5C A;  3E1V A;  3UCJ A; 
#chains in the Genus database with same CATH topology
 3VRK A;  3E2X A;  4ZNZ A;  3MF3 A;  1I6P A;  1T75 A;  3UCM A;  3TEN A;  4YF5 A;  3E31 A;  5SWC A;  3UCO A;  4RXY A;  4O1K A;  3E2A A;  3E3I A;  3E1W A;  2W3Q A;  3QY1 A;  5JJ8 A;  5BQ1 A;  3E24 A;  2W3N A;  4O1J A;  4WAK A;  1DDZ A;  2ESF A;  3E2W A;  3UCK A;  3E3F A;  3TEO A;  3VQJ A;  5CXK A;  4WAJ A;  4YF4 A;  3UCN A;  1I6O A;  4YF6 A;  1YM3 A;  1YLK A;  3E3G A;  2A8D A;  3EYX A;  1EKJ A;  3E28 A;  2A5V A;  3LAS A;  2A8C A;  4WAM A;  1G5C A;  3E1V A;  3UCJ A; 
#chains in the Genus database with same CATH homology
 3VRK A;  3E2X A;  4ZNZ A;  3MF3 A;  1I6P A;  1T75 A;  3UCM A;  3TEN A;  4YF5 A;  3E31 A;  5SWC A;  3UCO A;  4RXY A;  4O1K A;  3E2A A;  3E3I A;  3E1W A;  2W3Q A;  3QY1 A;  5JJ8 A;  5BQ1 A;  3E24 A;  2W3N A;  4O1J A;  4WAK A;  1DDZ A;  2ESF A;  3E2W A;  3UCK A;  3E3F A;  3TEO A;  3VQJ A;  5CXK A;  4WAJ A;  4YF4 A;  3UCN A;  1I6O A;  4YF6 A;  1YM3 A;  1YLK A;  3E3G A;  2A8D A;  3EYX A;  1EKJ A;  3E28 A;  2A5V A;  3LAS A;  2A8C A;  4WAM A;  1G5C A;  3E1V A;  3UCJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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