2ESFA

Identification of a novel non-catalytic bicarbonate binding site in eubacterial beta-carbonic anhydrase
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
213
structure length
213
Chain Sequence
DIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCGGVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGHSTIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of a Novel Noncatalytic Bicarbonate Binding Site in Eubacterial beta-Carbonic Anhydrase.
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords Carbonic anhydrase 2
total genus 77
structure length 213
sequence length 213
chains with identical sequence B
ec nomenclature ec 4.2.1.1: Carbonic anhydrase.
pdb deposition date 2005-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00484 Pro_CA Carbonic anhydrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1050.10 Alpha Beta 3-Layer(aba) Sandwich Beta-carbonic Anhydrase; Chain A Carbonic anhydrase 2esfA00
3LASA 4RXYA 4ZNZA 1EKJA 1G5CA 1I6OA 3VRKA 2A5VA 3E2AA 3E3GA 4O1JA 5BQ1A 4WAJA 4WAMA 1I6PA 3TENA 1DDZA 3UCKA 1YLKA 3E24A 2W3QA 3E28A 3UCNA 5CXKA 3QY1A 2A8CA 3EYXA 4O1KA 5JJ8A 3UCMA 1T75A 3E2XA 3VQJA 4WAKA 3E3IA 3MF3A 3UCJA 3E3FA 3TEOA 1YM3A 3E1WA 3E1VA 3UCOA 2A8DA 4YF5A 3E31A 4YF4A 2ESFA 5SWCA 4YF6A 3E2WA 2W3NA
chains in the Genus database with same CATH superfamily
3LASA 4RXYA 4ZNZA 1EKJA 1G5CA 1I6OA 3VRKA 2A5VA 3E2AA 3E3GA 4O1JA 5BQ1A 4WAJA 4WAMA 1I6PA 3TENA 1DDZA 3UCKA 1YLKA 3E24A 2W3QA 3E28A 3UCNA 5CXKA 3QY1A 2A8CA 3EYXA 4O1KA 5JJ8A 3UCMA 1T75A 3E2XA 3VQJA 4WAKA 3E3IA 3MF3A 3UCJA 3E3FA 3TEOA 1YM3A 3E1WA 3E1VA 3UCOA 2A8DA 4YF5A 3E31A 4YF4A 2ESFA 5SWCA 4YF6A 3E2WA 2W3NA
chains in the Genus database with same CATH topology
3LASA 4RXYA 4ZNZA 1EKJA 1G5CA 1I6OA 3VRKA 2A5VA 3E2AA 3E3GA 4O1JA 5BQ1A 4WAJA 4WAMA 1I6PA 3TENA 1DDZA 3UCKA 1YLKA 3E24A 2W3QA 3E28A 3UCNA 5CXKA 3QY1A 2A8CA 3EYXA 4O1KA 5JJ8A 3UCMA 1T75A 3E2XA 3VQJA 4WAKA 3E3IA 3MF3A 3UCJA 3E3FA 3TEOA 1YM3A 3E1WA 3E1VA 3UCOA 2A8DA 4YF5A 3E31A 4YF4A 2ESFA 5SWCA 4YF6A 3E2WA 2W3NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LAS A;  4RXY A;  4ZNZ A;  1EKJ A;  1G5C A;  1I6O A;  3VRK A;  2A5V A;  3E2A A;  3E3G A;  4O1J A;  5BQ1 A;  4WAJ A;  4WAM A;  1I6P A;  3TEN A;  1DDZ A;  3UCK A;  1YLK A;  3E24 A;  2W3Q A;  3E28 A;  3UCN A;  5CXK A;  3QY1 A;  2A8C A;  3EYX A;  4O1K A;  5JJ8 A;  3UCM A;  1T75 A;  3E2X A;  3VQJ A;  4WAK A;  3E3I A;  3MF3 A;  3UCJ A;  3E3F A;  3TEO A;  1YM3 A;  3E1W A;  3E1V A;  3UCO A;  2A8D A;  4YF5 A;  3E31 A;  4YF4 A;  2ESF A;  5SWC A;  4YF6 A;  3E2W A;  2W3N A; 
#chains in the Genus database with same CATH topology
 3LAS A;  4RXY A;  4ZNZ A;  1EKJ A;  1G5C A;  1I6O A;  3VRK A;  2A5V A;  3E2A A;  3E3G A;  4O1J A;  5BQ1 A;  4WAJ A;  4WAM A;  1I6P A;  3TEN A;  1DDZ A;  3UCK A;  1YLK A;  3E24 A;  2W3Q A;  3E28 A;  3UCN A;  5CXK A;  3QY1 A;  2A8C A;  3EYX A;  4O1K A;  5JJ8 A;  3UCM A;  1T75 A;  3E2X A;  3VQJ A;  4WAK A;  3E3I A;  3MF3 A;  3UCJ A;  3E3F A;  3TEO A;  1YM3 A;  3E1W A;  3E1V A;  3UCO A;  2A8D A;  4YF5 A;  3E31 A;  4YF4 A;  2ESF A;  5SWC A;  4YF6 A;  3E2W A;  2W3N A; 
#chains in the Genus database with same CATH homology
 3LAS A;  4RXY A;  4ZNZ A;  1EKJ A;  1G5C A;  1I6O A;  3VRK A;  2A5V A;  3E2A A;  3E3G A;  4O1J A;  5BQ1 A;  4WAJ A;  4WAM A;  1I6P A;  3TEN A;  1DDZ A;  3UCK A;  1YLK A;  3E24 A;  2W3Q A;  3E28 A;  3UCN A;  5CXK A;  3QY1 A;  2A8C A;  3EYX A;  4O1K A;  5JJ8 A;  3UCM A;  1T75 A;  3E2X A;  3VQJ A;  4WAK A;  3E3I A;  3MF3 A;  3UCJ A;  3E3F A;  3TEO A;  1YM3 A;  3E1W A;  3E1V A;  3UCO A;  2A8D A;  4YF5 A;  3E31 A;  4YF4 A;  2ESF A;  5SWC A;  4YF6 A;  3E2W A;  2W3N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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