2H42A

Crystal structure of pde5 in complex with sildenafil
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
326
structure length
326
Chain Sequence
EETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords cGMP-specific 3',5'-cyclic phosphodiesterase
total genus 131
structure length 326
sequence length 326
chains with identical sequence B, C
ec nomenclature ec 3.1.4.35: 3',5'-cyclic-GMP phosphodiesterase.
pdb deposition date 2006-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00233 PDEase_I 3'5'-cyclic nucleotide phosphodiesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1300.10 Mainly Alpha Orthogonal Bundle Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 2h42A00
3LXGA 4KP6A 3G45A 1UDTA 2CHMA 4C1IA 1RORA 1Y2CA 4MSHA 3LY2A 4Y86A 4WCUA 4LLKA 4PM0A 3HMVA 3G4KA 4NPVA 5EDIB 3I8VA 1SOJA 4I15A 4Y8CA 4ZO5A 1XMYB 1XOZA 2FM5A 4MD6A 2OVYA 4HTZA 3HQZA 3WYKA 3SL5A 5DH4A 1UHOA 4JIBA 2O8HA 3G4LA 5K32A 4Y87A 2QYNA 3UUOA 1PTWA 4YS7A 3K3HA 4TPMA 3DY8A 4D09A 1UDUA 4GH6A 4LM1A 4NPWA 5C1WA 3SN7A 3DYQA 3QPNA 1Y2BA 3G4GA 2HD1A 3FRGA 3ITMA 4AJMA 3V94A 3DYSA 4DFFA 1Y2DA 5EDEB 3TVXA 4LKQA 5K1IA 4P0NA 2R8QA 5C2EA 2OUUA 2YY2A 4P1RA 3SNIA 2H40A 4PHLA 4LM3A 3G4IA 5EDIA 3O56A 4D08A 5C29A 1MKDA 1XMYA 1XOQA 2QYKA 4NW7A 1OYNA 4MRWA 3DYNA 4LLPA 5AXQA 3WS8A 1ZKNA 3QI3A 5C2AA 1XOTA 3O57A 4MYQA 3HC8A 4OEWA 4MS0A 2H42A 4FCDA 4MSAA 2FM0A 4MVHA 4I9ZA 1XORA 5DH5A 3SL8A 3IADA 4IA0A 4AJGA 1TBBA 1T9SA 2OUSA 1XP0A 3JWQA 4MUWA 4HEUA 4AJFA 1XM4A 4XY2A 3V9BA 1TBFA 1SO2A 4TPPA 5B25A 3K3EA 5C2HA 3K4SA 1TAZA 3HDZA 4BBXA 3UI7A 2WEYA 4E90A 3SL3A 3WS9A 1ZKLA 3HR1A 4G2YA 4AELA 3W5EA 5EDEA 4DDLA 5I2RA 4WN1A 1XMUB 3SL4A 1Y2HA 1XOMA 3B2RA 3G3NA 5K9RA 3HQWA 4HF4A 1TB5A 4LLXA 4X0FA 2OUNA 3SNLA 3WYMA 3ECNA 4FCBA 4W1OA 3ITUA 4AJDA 5EDGB 3G58A 5EDHA 2OURA 3BJCA 3JWRA 3JSWA 3WD9A 1RO6A 4HTXA 4MSEA 2OUPA 3WI2A 2QYMA 1XLZA 4PHWA 3N3ZA 2OUQA 4Y2BA 1Q9MA 2OUVA 3SIEA 2PW3A 3HQYA 3WYLA 2Y0JA 3QPOA 1Y2KA 4LM4A 2OUYA 3TGEA 4G2WA 4G2JA 4WZIA 5AXPA 1F0JA 1XN0A 3KKTA 5B4LA 5C28A 1XLXA 3IBJA 4LM2A 1XMUA 4QGEA 1Z1LA 1T9RA 4OEXA 4MSNA 4MSCA 4LLJA 2H44A 3D3PA 4LM0A 5B4KA 3SHYA 3JSIA 3V93A 1XM6A 1Y2JA 3SL6A 5EDGA 2QYLA 4MRZA 4YQHA 4G2LA 3ECMA 1RKPA 3DYLA 1RO9A 1XM4B 1XONA 3O0JA 1Y2EA 2OVVA 3QI4A 3QPPA 3GWTA 1XOSA 4OGBA 1TB7A 3TGGA 3SHZA 3IAKA
chains in the Genus database with same CATH superfamily
3LXGA 4KP6A 3G45A 1UDTA 2CHMA 4C1IA 1RORA 1Y2CA 4MSHA 3LY2A 4Y86A 4WCUA 4LLKA 4PM0A 3HMVA 3G4KA 4NPVA 5EDIB 3I8VA 1SOJA 4I15A 4Y8CA 4ZO5A 1XMYB 1XOZA 2FM5A 4MD6A 2OVYA 4HTZA 3HQZA 3WYKA 3SL5A 5DH4A 1UHOA 4JIBA 2O8HA 3G4LA 5K32A 4Y87A 2QYNA 3UUOA 1PTWA 4YS7A 3K3HA 4TPMA 3DY8A 4D09A 1UDUA 4GH6A 4LM1A 4NPWA 5C1WA 3SN7A 3DYQA 3QPNA 1Y2BA 3G4GA 2HD1A 3FRGA 3ITMA 4AJMA 3V94A 3DYSA 4DFFA 1Y2DA 5EDEB 3TVXA 4LKQA 5K1IA 4P0NA 2R8QA 5C2EA 2OUUA 2YY2A 4P1RA 3SNIA 2H40A 4PHLA 4LM3A 3G4IA 5EDIA 3O56A 4D08A 5C29A 1MKDA 1XMYA 1XOQA 2QYKA 4NW7A 1OYNA 4MRWA 3DYNA 4LLPA 5AXQA 3WS8A 1ZKNA 3QI3A 5C2AA 1XOTA 3O57A 4MYQA 3HC8A 4OEWA 4MS0A 2H42A 4FCDA 4MSAA 2FM0A 4MVHA 4I9ZA 1XORA 5DH5A 3SL8A 3IADA 4IA0A 4AJGA 1TBBA 1T9SA 2OUSA 1XP0A 3JWQA 4MUWA 4HEUA 4AJFA 1XM4A 4XY2A 3V9BA 1TBFA 1SO2A 4TPPA 5B25A 3K3EA 5C2HA 3K4SA 1TAZA 3HDZA 4BBXA 3UI7A 2WEYA 4E90A 3SL3A 3WS9A 1ZKLA 3HR1A 4G2YA 4AELA 3W5EA 5EDEA 4DDLA 5I2RA 4WN1A 1XMUB 3SL4A 1Y2HA 1XOMA 3B2RA 3G3NA 5K9RA 3HQWA 4HF4A 1TB5A 4LLXA 4X0FA 2OUNA 3SNLA 3WYMA 3ECNA 4FCBA 4W1OA 3ITUA 4AJDA 5EDGB 3G58A 5EDHA 2OURA 3BJCA 3JWRA 3JSWA 3WD9A 1RO6A 4HTXA 4MSEA 2OUPA 3WI2A 2QYMA 1XLZA 4PHWA 3N3ZA 2OUQA 4Y2BA 1Q9MA 2OUVA 3SIEA 2PW3A 3HQYA 3WYLA 2Y0JA 3QPOA 1Y2KA 4LM4A 2OUYA 3TGEA 4G2WA 4G2JA 4WZIA 5AXPA 1F0JA 1XN0A 3KKTA 5B4LA 5C28A 1XLXA 3IBJA 4LM2A 1XMUA 4QGEA 1Z1LA 1T9RA 4OEXA 4MSNA 4MSCA 4LLJA 2H44A 3D3PA 4LM0A 5B4KA 3SHYA 3JSIA 3V93A 1XM6A 1Y2JA 3SL6A 5EDGA 2QYLA 4MRZA 4YQHA 4G2LA 3ECMA 1RKPA 3DYLA 1RO9A 1XM4B 1XONA 3O0JA 1Y2EA 2OVVA 3QI4A 3QPPA 3GWTA 1XOSA 4OGBA 1TB7A 3TGGA 3SHZA 3IAKA
chains in the Genus database with same CATH topology
3LXGA 4KP6A 3G45A 1UDTA 2CHMA 4C1IA 1RORA 1Y2CA 4MSHA 3LY2A 4Y86A 4WCUA 4LLKA 4PM0A 3HMVA 3G4KA 4NPVA 5EDIB 3I8VA 1SOJA 4I15A 4Y8CA 4ZO5A 1XMYB 1XOZA 2FM5A 4MD6A 2OVYA 4HTZA 3HQZA 3WYKA 3SL5A 5DH4A 1UHOA 4JIBA 2O8HA 3G4LA 5K32A 4Y87A 2QYNA 3UUOA 1PTWA 4YS7A 3K3HA 4TPMA 3DY8A 4D09A 1UDUA 4GH6A 4LM1A 4NPWA 5C1WA 3SN7A 3DYQA 3QPNA 1Y2BA 3G4GA 2HD1A 3FRGA 3ITMA 4AJMA 3V94A 3DYSA 4DFFA 1Y2DA 5EDEB 3TVXA 4LKQA 5K1IA 4P0NA 2R8QA 5C2EA 2OUUA 2YY2A 4P1RA 3SNIA 2H40A 4PHLA 4LM3A 3G4IA 5EDIA 3O56A 4D08A 5C29A 1MKDA 1XMYA 1XOQA 2QYKA 4NW7A 1OYNA 4MRWA 3DYNA 4LLPA 5AXQA 3WS8A 1ZKNA 3QI3A 5C2AA 1XOTA 3O57A 4MYQA 3HC8A 4OEWA 4MS0A 2H42A 4FCDA 4MSAA 2FM0A 4MVHA 4I9ZA 1XORA 5DH5A 3SL8A 3IADA 4IA0A 4AJGA 1TBBA 1T9SA 2OUSA 1XP0A 3JWQA 4MUWA 4HEUA 4AJFA 1XM4A 4XY2A 3V9BA 1TBFA 1SO2A 4TPPA 5B25A 3K3EA 5C2HA 3K4SA 1TAZA 3HDZA 4BBXA 3UI7A 2WEYA 4E90A 3SL3A 3WS9A 1ZKLA 3HR1A 4G2YA 4AELA 3W5EA 5EDEA 4DDLA 5I2RA 4WN1A 1XMUB 3SL4A 1Y2HA 1XOMA 3B2RA 3G3NA 5K9RA 3HQWA 4HF4A 1TB5A 4LLXA 4X0FA 2OUNA 3SNLA 3WYMA 3ECNA 4FCBA 4W1OA 3ITUA 4AJDA 5EDGB 3G58A 5EDHA 2OURA 3BJCA 3JWRA 3JSWA 3WD9A 1RO6A 4HTXA 4MSEA 2OUPA 3WI2A 2QYMA 1XLZA 4PHWA 3N3ZA 2OUQA 4Y2BA 1Q9MA 2OUVA 3SIEA 2PW3A 3HQYA 3WYLA 2Y0JA 3QPOA 1Y2KA 4LM4A 2OUYA 3TGEA 4G2WA 4G2JA 4WZIA 5AXPA 1F0JA 1XN0A 3KKTA 5B4LA 5C28A 1XLXA 3IBJA 4LM2A 1XMUA 4QGEA 1Z1LA 1T9RA 4OEXA 4MSNA 4MSCA 4LLJA 2H44A 3D3PA 4LM0A 5B4KA 3SHYA 3JSIA 3V93A 1XM6A 1Y2JA 3SL6A 5EDGA 2QYLA 4MRZA 4YQHA 4G2LA 3ECMA 1RKPA 3DYLA 1RO9A 1XM4B 1XONA 3O0JA 1Y2EA 2OVVA 3QI4A 3QPPA 3GWTA 1XOSA 4OGBA 1TB7A 3TGGA 3SHZA 3IAKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LXG A;  4KP6 A;  3G45 A;  1UDT A;  2CHM A;  4C1I A;  1ROR A;  1Y2C A;  4MSH A;  3LY2 A;  4Y86 A;  4WCU A;  4LLK A;  4PM0 A;  3HMV A;  3G4K A;  4NPV A;  5EDI B;  3I8V A;  1SOJ A;  4I15 A;  4Y8C A;  4ZO5 A;  1XMY B;  1XOZ A;  2FM5 A;  4MD6 A;  2OVY A;  4HTZ A;  3HQZ A;  3WYK A;  3SL5 A;  5DH4 A;  1UHO A;  4JIB A;  2O8H A;  3G4L A;  5K32 A;  4Y87 A;  2QYN A;  3UUO A;  1PTW A;  4YS7 A;  3K3H A;  4TPM A;  3DY8 A;  4D09 A;  1UDU A;  4GH6 A;  4LM1 A;  4NPW A;  5C1W A;  3SN7 A;  3DYQ A;  3QPN A;  1Y2B A;  3G4G A;  2HD1 A;  3FRG A;  3ITM A;  4AJM A;  3V94 A;  3DYS A;  4DFF A;  1Y2D A;  5EDE B;  3TVX A;  4LKQ A;  5K1I A;  4P0N A;  2R8Q A;  5C2E A;  2OUU A;  2YY2 A;  4P1R A;  3SNI A;  2H40 A;  4PHL A;  4LM3 A;  3G4I A;  5EDI A;  3O56 A;  4D08 A;  5C29 A;  1MKD A;  1XMY A;  1XOQ A;  2QYK A;  4NW7 A;  1OYN A;  4MRW A;  3DYN A;  4LLP A;  5AXQ A;  3WS8 A;  1ZKN A;  3QI3 A;  5C2A A;  1XOT A;  3O57 A;  4MYQ A;  3HC8 A;  4OEW A;  4MS0 A;  2H42 A;  4FCD A;  4MSA A;  2FM0 A;  4MVH A;  4I9Z A;  1XOR A;  5DH5 A;  3SL8 A;  3IAD A;  4IA0 A;  4AJG A;  1TBB A;  1T9S A;  2OUS A;  1XP0 A;  3JWQ A;  4MUW A;  4HEU A;  4AJF A;  1XM4 A;  4XY2 A;  3V9B A;  1TBF A;  1SO2 A;  4TPP A;  5B25 A;  3K3E A;  5C2H A;  3K4S A;  1TAZ A;  3HDZ A;  4BBX A;  3UI7 A;  2WEY A;  4E90 A;  3SL3 A;  3WS9 A;  1ZKL A;  3HR1 A;  4G2Y A;  4AEL A;  3W5E A;  5EDE A;  4DDL A;  5I2R A;  4WN1 A;  1XMU B;  3SL4 A;  1Y2H A;  1XOM A;  3B2R A;  3G3N A;  5K9R A;  3HQW A;  4HF4 A;  1TB5 A;  4LLX A;  4X0F A;  2OUN A;  3SNL A;  3WYM A;  3ECN A;  4FCB A;  4W1O A;  3ITU A;  4AJD A;  5EDG B;  3G58 A;  5EDH A;  2OUR A;  3BJC A;  3JWR A;  3JSW A;  3WD9 A;  1RO6 A;  4HTX A;  4MSE A;  2OUP A;  3WI2 A;  2QYM A;  1XLZ A;  4PHW A;  3N3Z A;  2OUQ A;  4Y2B A;  1Q9M A;  2OUV A;  3SIE A;  2PW3 A;  3HQY A;  3WYL A;  2Y0J A;  3QPO A;  1Y2K A;  4LM4 A;  2OUY A;  3TGE A;  4G2W A;  4G2J A;  4WZI A;  5AXP A;  1F0J A;  1XN0 A;  3KKT A;  5B4L A;  5C28 A;  1XLX A;  3IBJ A;  4LM2 A;  1XMU A;  4QGE A;  1Z1L A;  1T9R A;  4OEX A;  4MSN A;  4MSC A;  4LLJ A;  2H44 A;  3D3P A;  4LM0 A;  5B4K A;  3SHY A;  3JSI A;  3V93 A;  1XM6 A;  1Y2J A;  3SL6 A;  5EDG A;  2QYL A;  4MRZ A;  4YQH A;  4G2L A;  3ECM A;  1RKP A;  3DYL A;  1RO9 A;  1XM4 B;  1XON A;  3O0J A;  1Y2E A;  2OVV A;  3QI4 A;  3QPP A;  3GWT A;  1XOS A;  4OGB A;  1TB7 A;  3TGG A;  3SHZ A;  3IAK A; 
#chains in the Genus database with same CATH topology
 3LXG A;  4KP6 A;  3G45 A;  1UDT A;  2CHM A;  4C1I A;  1ROR A;  1Y2C A;  4MSH A;  3LY2 A;  4Y86 A;  4WCU A;  4LLK A;  4PM0 A;  3HMV A;  3G4K A;  4NPV A;  5EDI B;  3I8V A;  1SOJ A;  4I15 A;  4Y8C A;  4ZO5 A;  1XMY B;  1XOZ A;  2FM5 A;  4MD6 A;  2OVY A;  4HTZ A;  3HQZ A;  3WYK A;  3SL5 A;  5DH4 A;  1UHO A;  4JIB A;  2O8H A;  3G4L A;  5K32 A;  4Y87 A;  2QYN A;  3UUO A;  1PTW A;  4YS7 A;  3K3H A;  4TPM A;  3DY8 A;  4D09 A;  1UDU A;  4GH6 A;  4LM1 A;  4NPW A;  5C1W A;  3SN7 A;  3DYQ A;  3QPN A;  1Y2B A;  3G4G A;  2HD1 A;  3FRG A;  3ITM A;  4AJM A;  3V94 A;  3DYS A;  4DFF A;  1Y2D A;  5EDE B;  3TVX A;  4LKQ A;  5K1I A;  4P0N A;  2R8Q A;  5C2E A;  2OUU A;  2YY2 A;  4P1R A;  3SNI A;  2H40 A;  4PHL A;  4LM3 A;  3G4I A;  5EDI A;  3O56 A;  4D08 A;  5C29 A;  1MKD A;  1XMY A;  1XOQ A;  2QYK A;  4NW7 A;  1OYN A;  4MRW A;  3DYN A;  4LLP A;  5AXQ A;  3WS8 A;  1ZKN A;  3QI3 A;  5C2A A;  1XOT A;  3O57 A;  4MYQ A;  3HC8 A;  4OEW A;  4MS0 A;  2H42 A;  4FCD A;  4MSA A;  2FM0 A;  4MVH A;  4I9Z A;  1XOR A;  5DH5 A;  3SL8 A;  3IAD A;  4IA0 A;  4AJG A;  1TBB A;  1T9S A;  2OUS A;  1XP0 A;  3JWQ A;  4MUW A;  4HEU A;  4AJF A;  1XM4 A;  4XY2 A;  3V9B A;  1TBF A;  1SO2 A;  4TPP A;  5B25 A;  3K3E A;  5C2H A;  3K4S A;  1TAZ A;  3HDZ A;  4BBX A;  3UI7 A;  2WEY A;  4E90 A;  3SL3 A;  3WS9 A;  1ZKL A;  3HR1 A;  4G2Y A;  4AEL A;  3W5E A;  5EDE A;  4DDL A;  5I2R A;  4WN1 A;  1XMU B;  3SL4 A;  1Y2H A;  1XOM A;  3B2R A;  3G3N A;  5K9R A;  3HQW A;  4HF4 A;  1TB5 A;  4LLX A;  4X0F A;  2OUN A;  3SNL A;  3WYM A;  3ECN A;  4FCB A;  4W1O A;  3ITU A;  4AJD A;  5EDG B;  3G58 A;  5EDH A;  2OUR A;  3BJC A;  3JWR A;  3JSW A;  3WD9 A;  1RO6 A;  4HTX A;  4MSE A;  2OUP A;  3WI2 A;  2QYM A;  1XLZ A;  4PHW A;  3N3Z A;  2OUQ A;  4Y2B A;  1Q9M A;  2OUV A;  3SIE A;  2PW3 A;  3HQY A;  3WYL A;  2Y0J A;  3QPO A;  1Y2K A;  4LM4 A;  2OUY A;  3TGE A;  4G2W A;  4G2J A;  4WZI A;  5AXP A;  1F0J A;  1XN0 A;  3KKT A;  5B4L A;  5C28 A;  1XLX A;  3IBJ A;  4LM2 A;  1XMU A;  4QGE A;  1Z1L A;  1T9R A;  4OEX A;  4MSN A;  4MSC A;  4LLJ A;  2H44 A;  3D3P A;  4LM0 A;  5B4K A;  3SHY A;  3JSI A;  3V93 A;  1XM6 A;  1Y2J A;  3SL6 A;  5EDG A;  2QYL A;  4MRZ A;  4YQH A;  4G2L A;  3ECM A;  1RKP A;  3DYL A;  1RO9 A;  1XM4 B;  1XON A;  3O0J A;  1Y2E A;  2OVV A;  3QI4 A;  3QPP A;  3GWT A;  1XOS A;  4OGB A;  1TB7 A;  3TGG A;  3SHZ A;  3IAK A; 
#chains in the Genus database with same CATH homology
 3LXG A;  4KP6 A;  3G45 A;  1UDT A;  2CHM A;  4C1I A;  1ROR A;  1Y2C A;  4MSH A;  3LY2 A;  4Y86 A;  4WCU A;  4LLK A;  4PM0 A;  3HMV A;  3G4K A;  4NPV A;  5EDI B;  3I8V A;  1SOJ A;  4I15 A;  4Y8C A;  4ZO5 A;  1XMY B;  1XOZ A;  2FM5 A;  4MD6 A;  2OVY A;  4HTZ A;  3HQZ A;  3WYK A;  3SL5 A;  5DH4 A;  1UHO A;  4JIB A;  2O8H A;  3G4L A;  5K32 A;  4Y87 A;  2QYN A;  3UUO A;  1PTW A;  4YS7 A;  3K3H A;  4TPM A;  3DY8 A;  4D09 A;  1UDU A;  4GH6 A;  4LM1 A;  4NPW A;  5C1W A;  3SN7 A;  3DYQ A;  3QPN A;  1Y2B A;  3G4G A;  2HD1 A;  3FRG A;  3ITM A;  4AJM A;  3V94 A;  3DYS A;  4DFF A;  1Y2D A;  5EDE B;  3TVX A;  4LKQ A;  5K1I A;  4P0N A;  2R8Q A;  5C2E A;  2OUU A;  2YY2 A;  4P1R A;  3SNI A;  2H40 A;  4PHL A;  4LM3 A;  3G4I A;  5EDI A;  3O56 A;  4D08 A;  5C29 A;  1MKD A;  1XMY A;  1XOQ A;  2QYK A;  4NW7 A;  1OYN A;  4MRW A;  3DYN A;  4LLP A;  5AXQ A;  3WS8 A;  1ZKN A;  3QI3 A;  5C2A A;  1XOT A;  3O57 A;  4MYQ A;  3HC8 A;  4OEW A;  4MS0 A;  2H42 A;  4FCD A;  4MSA A;  2FM0 A;  4MVH A;  4I9Z A;  1XOR A;  5DH5 A;  3SL8 A;  3IAD A;  4IA0 A;  4AJG A;  1TBB A;  1T9S A;  2OUS A;  1XP0 A;  3JWQ A;  4MUW A;  4HEU A;  4AJF A;  1XM4 A;  4XY2 A;  3V9B A;  1TBF A;  1SO2 A;  4TPP A;  5B25 A;  3K3E A;  5C2H A;  3K4S A;  1TAZ A;  3HDZ A;  4BBX A;  3UI7 A;  2WEY A;  4E90 A;  3SL3 A;  3WS9 A;  1ZKL A;  3HR1 A;  4G2Y A;  4AEL A;  3W5E A;  5EDE A;  4DDL A;  5I2R A;  4WN1 A;  1XMU B;  3SL4 A;  1Y2H A;  1XOM A;  3B2R A;  3G3N A;  5K9R A;  3HQW A;  4HF4 A;  1TB5 A;  4LLX A;  4X0F A;  2OUN A;  3SNL A;  3WYM A;  3ECN A;  4FCB A;  4W1O A;  3ITU A;  4AJD A;  5EDG B;  3G58 A;  5EDH A;  2OUR A;  3BJC A;  3JWR A;  3JSW A;  3WD9 A;  1RO6 A;  4HTX A;  4MSE A;  2OUP A;  3WI2 A;  2QYM A;  1XLZ A;  4PHW A;  3N3Z A;  2OUQ A;  4Y2B A;  1Q9M A;  2OUV A;  3SIE A;  2PW3 A;  3HQY A;  3WYL A;  2Y0J A;  3QPO A;  1Y2K A;  4LM4 A;  2OUY A;  3TGE A;  4G2W A;  4G2J A;  4WZI A;  5AXP A;  1F0J A;  1XN0 A;  3KKT A;  5B4L A;  5C28 A;  1XLX A;  3IBJ A;  4LM2 A;  1XMU A;  4QGE A;  1Z1L A;  1T9R A;  4OEX A;  4MSN A;  4MSC A;  4LLJ A;  2H44 A;  3D3P A;  4LM0 A;  5B4K A;  3SHY A;  3JSI A;  3V93 A;  1XM6 A;  1Y2J A;  3SL6 A;  5EDG A;  2QYL A;  4MRZ A;  4YQH A;  4G2L A;  3ECM A;  1RKP A;  3DYL A;  1RO9 A;  1XM4 B;  1XON A;  3O0J A;  1Y2E A;  2OVV A;  3QI4 A;  3QPP A;  3GWT A;  1XOS A;  4OGB A;  1TB7 A;  3TGG A;  3SHZ A;  3IAK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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