2KBYA

The tetramerization domain of human p73
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
48
structure length
48
Chain Sequence
DEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational stability and activity of p73 require a second helix in the tetramerization domain.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Tumor protein p73
total genus 14
structure length 48
sequence length 48
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2008-12-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.170.10 Few Secondary Structures Irregular p53, subunit A p53-like tetramerisation domain 2kbyA00
1SAFA 2KBYA 5HOCA 1SAEA 1OLHA 4A9ZA 5HOBA 1OLGA 3SAKA 1SALA 2MW4A 3ZY1A 2WTTA 1SAKA 2WQIA
chains in the Genus database with same CATH superfamily
1SAFA 2KBYA 5HOCA 1SAEA 1OLHA 4A9ZA 5HOBA 1OLGA 3SAKA 1SALA 2MW4A 3ZY1A 2WTTA 1SAKA 2WQIA
chains in the Genus database with same CATH topology
1SAFA 2KBYA 5HOCA 1SAEA 1OLHA 4A9ZA 5HOBA 1OLGA 3SAKA 1SALA 2MW4A 3ZY1A 2WTTA 1SAKA 2WQIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SAF A;  2KBY A;  5HOC A;  1SAE A;  1OLH A;  4A9Z A;  5HOB A;  1OLG A;  3SAK A;  1SAL A;  2MW4 A;  3ZY1 A;  2WTT A;  1SAK A;  2WQI A; 
#chains in the Genus database with same CATH topology
 1SAF A;  2KBY A;  5HOC A;  1SAE A;  1OLH A;  4A9Z A;  5HOB A;  1OLG A;  3SAK A;  1SAL A;  2MW4 A;  3ZY1 A;  2WTT A;  1SAK A;  2WQI A; 
#chains in the Genus database with same CATH homology
 1SAF A;  2KBY A;  5HOC A;  1SAE A;  1OLH A;  4A9Z A;  5HOB A;  1OLG A;  3SAK A;  1SAL A;  2MW4 A;  3ZY1 A;  2WTT A;  1SAK A;  2WQI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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