2LCTB

Solution structure of the vav1 sh2 domain complexed with a syk-derived doubly phosphorylated peptide
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
13
structure length
11
Chain Sequence
DTEVESPADPE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Proto-oncogene vav
structure length 11
sequence length 13
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2011-05-09
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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