2OXVA

Structure of the a138t promiscuous mutant of the ecori restriction endonuclease bound to its cognate recognition site.
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
261
structure length
261
Chain Sequence
SQGVIGIFGDYAKAHDLAVGEVSKLVKKALSNEYPQLSFRYRDSIKKTEINEALKKIDPDLGGTLFVSNSSIKPDGGIVEVKDDYGEWRVVLVAEAKHQGKDIINIRNGLLVGKRGDQDLMTAGNAIERSHKNISEIANFMLSESHFPYVLFLEGSNFLTENISITRPDGRVVNLEYNSGILNRLDRLTAANYGMPINSNLCINKFVNHKDKSIMLQAASIYTQGDGREWDSKIMFEIMFDISTTSLRVLGRDLFEQLTSK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/dna
molecule keywords DNA (5'-D(*TP*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
publication title Structural and thermodynamic basis for enhanced DNA binding by a promiscuous mutant EcoRI endonuclease.
pubmed doi rcsb
source organism Escherichia coli
total genus 86
structure length 261
sequence length 261
ec nomenclature ec 3.1.21.4: Type II site-specific deoxyribonuclease.
pdb deposition date 2007-02-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02963 EcoRI Restriction endonuclease EcoRI
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.580.10 Alpha Beta 3-Layer(aba) Sandwich ECO RI Endonuclease; Chain A Eco RI Endonuclease, subunit A 2oxvA00
1QPSA 1QRIA 2OXVA 1QRHA 1CL8A 1D02A 1QC9A 1CKQA 1ERIA
chains in the Genus database with same CATH superfamily
1QPSA 1QRIA 2OXVA 1QRHA 1CL8A 1D02A 1QC9A 1CKQA 1ERIA
chains in the Genus database with same CATH topology
1QPSA 1QRIA 2OXVA 1QRHA 1CL8A 1D02A 1QC9A 1CKQA 1ERIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QPS A;  1QRI A;  2OXV A;  1QRH A;  1CL8 A;  1D02 A;  1QC9 A;  1CKQ A;  1ERI A; 
#chains in the Genus database with same CATH topology
 1QPS A;  1QRI A;  2OXV A;  1QRH A;  1CL8 A;  1D02 A;  1QC9 A;  1CKQ A;  1ERI A; 
#chains in the Genus database with same CATH homology
 1QPS A;  1QRI A;  2OXV A;  1QRH A;  1CL8 A;  1D02 A;  1QC9 A;  1CKQ A;  1ERI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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