2PY4A

Full length structure of the mycobacterium tuberculosis dutpase complexed with magnesium and alpha,beta-imido-dutp.
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
153
structure length
153
Chain Sequence
STTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEAGLASTSRGDGGHGSSGGHASL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 23
structure length 153
sequence length 153
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2007-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 2py4A00
2QLPA 4GCYA 4DHKA 3TS6A 1XS1A 1F7OA 2HR6A 2WE2A 1DUCA 3TP1A 2XCDA 2Y8CA 4GV8A 4A6AA 2WE1A 1XS4A 2BSYA 4OOPA 3F4FA 3H6DA 1F7PA 1DUTA 3ZF1A 3T60A 3HHQA 3EHWA 4AOOA 2J4QA 3MBQA 1VYQA 3LOJA 5CCTA 1PKHA 3C3IA 1XS6A 3H6XA 3ZF4A 1F7KA 1PKJA 5EDDA 2HXBA 3TPWA 1MQ7A 4LHRA 1DUDA 3TSLA 3I93A 3TRNA 2D4MA 1PKKA 4OOQA 3TQZA 4B0HA 3SO2A 2R9QA 2ZDCA 2XCEA 5ECTA 2HRMA 1SM8A 2V9XA 3KM3A 3C2TA 3TPNA 4AOZA 3ZF0A 3ZF2A 1EU5A 3TQ5A 3TTAA 4XJCA 3MDXA 2OKDA 2WE0A 3CA9A 4APZ1 2PY4A 2YZJA 3TQ3A 3ARNA 2WE3A 1SYLA 2J4HA 2QXXA 1F7NA 1DUPA 1OGHA 2Y1TA 2XY3A 1Q5HA 3ARAA 5CCOA 2D4LA 4AO5A 3LQWA 2BAZA 4WRKA 1F7RA 3ZEZA 3GF0A 1Q5UX 2OKBA 2OL0A 2XX6A 1RNJA 1SEHA 3T6YA 1SIXA 1F7QA 1DUNA 2OKEA 3ECYA 2HQUA 2PC5A 3T70A 1SLHA 1EUWA 1SMCA 3TQ4A 3ZF6A 3TPYA 3ZF3A 2D4NA 2OL1A 3T64A 1SNFA 4GK6A 1RN8A 1F7DA 3HZAA 5F9KA 3TRLA 3ZF5A 1SJNA 3TPSA 3P48A 2HXDA 2BT1A
chains in the Genus database with same CATH superfamily
2QLPA 4GCYA 4DHKA 3TS6A 1XS1A 1F7OA 2HR6A 2WE2A 1DUCA 3TP1A 2XCDA 2Y8CA 4GV8A 4A6AA 2WE1A 1XS4A 2BSYA 4OOPA 3F4FA 3H6DA 1F7PA 1DUTA 3ZF1A 3T60A 3HHQA 3EHWA 4AOOA 2J4QA 3MBQA 1VYQA 3LOJA 5CCTA 1PKHA 3C3IA 1XS6A 3H6XA 3ZF4A 1F7KA 1PKJA 5EDDA 2HXBA 3TPWA 1MQ7A 4LHRA 1DUDA 3TSLA 3I93A 3TRNA 2D4MA 1PKKA 4OOQA 3TQZA 4B0HA 3SO2A 2R9QA 2ZDCA 2XCEA 5ECTA 2HRMA 1SM8A 2V9XA 3KM3A 3C2TA 3TPNA 4AOZA 3ZF0A 3ZF2A 1EU5A 3TQ5A 3TTAA 4XJCA 3MDXA 2OKDA 2WE0A 3CA9A 4APZ1 2PY4A 2YZJA 3TQ3A 3ARNA 1TULA 2WE3A 1SYLA 2J4HA 2QXXA 1F7NA 1DUPA 1OGHA 2Y1TA 2XY3A 1Q5HA 3ARAA 5CCOA 2D4LA 4AO5A 3LQWA 2BAZA 4WRKA 1F7RA 3ZEZA 3GF0A 1Q5UX 2OKBA 2OL0A 2XX6A 1RNJA 1SEHA 3T6YA 1SIXA 1F7QA 1DUNA 2OKEA 3ECYA 2HQUA 2PC5A 3T70A 1SLHA 1EUWA 1SMCA 3TQ4A 3ZF6A 3TPYA 3ZF3A 2D4NA 2OL1A 3T64A 1SNFA 4GK6A 1RN8A 1F7DA 3HZAA 5F9KA 3TRLA 3ZF5A 1SJNA 3TPSA 3P48A 2HXDA 2BT1A
chains in the Genus database with same CATH topology
2QLPA 4GCYA 4DHKA 3TS6A 1XS1A 1F7OA 2HR6A 2WE2A 1DUCA 3TP1A 2XCDA 2Y8CA 4GV8A 4A6AA 2WE1A 1XS4A 2BSYA 4OOPA 3F4FA 3H6DA 1F7PA 1DUTA 3ZF1A 3T60A 3HHQA 3EHWA 4AOOA 2J4QA 3MBQA 1VYQA 3LOJA 5CCTA 1PKHA 3C3IA 1XS6A 3H6XA 3ZF4A 1F7KA 1PKJA 5EDDA 2HXBA 3TPWA 1MQ7A 4LHRA 1DUDA 3TSLA 3I93A 3TRNA 2D4MA 1PKKA 4OOQA 3TQZA 4B0HA 3SO2A 2R9QA 2ZDCA 2XCEA 5ECTA 2HRMA 1SM8A 2V9XA 3KM3A 3C2TA 3TPNA 4AOZA 3ZF0A 3ZF2A 1EU5A 3TQ5A 3TTAA 4XJCA 3MDXA 2OKDA 2WE0A 3CA9A 4APZ1 2PY4A 2YZJA 3TQ3A 3ARNA 2WE3A 1SYLA 2J4HA 2QXXA 1F7NA 1DUPA 1OGHA 2Y1TA 2XY3A 1Q5HA 3ARAA 5CCOA 2D4LA 4AO5A 3LQWA 2BAZA 4WRKA 1F7RA 3ZEZA 3GF0A 1Q5UX 2OKBA 2OL0A 2XX6A 1RNJA 1SEHA 3T6YA 1SIXA 1F7QA 1DUNA 2OKEA 3ECYA 2HQUA 2PC5A 3T70A 1SLHA 1EUWA 1SMCA 3TQ4A 3ZF6A 3TPYA 3ZF3A 2D4NA 2OL1A 3T64A 1SNFA 4GK6A 1RN8A 1F7DA 3HZAA 5F9KA 3TRLA 3ZF5A 1SJNA 3TPSA 3P48A 2HXDA 2BT1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QLP A;  4GCY A;  4DHK A;  3TS6 A;  1XS1 A;  1F7O A;  2HR6 A;  2WE2 A;  1DUC A;  3TP1 A;  2XCD A;  2Y8C A;  4GV8 A;  4A6A A;  2WE1 A;  1XS4 A;  2BSY A;  4OOP A;  3F4F A;  3H6D A;  1F7P A;  1DUT A;  3ZF1 A;  3T60 A;  3HHQ A;  3EHW A;  4AOO A;  2J4Q A;  3MBQ A;  1VYQ A;  3LOJ A;  5CCT A;  1PKH A;  3C3I A;  1XS6 A;  3H6X A;  3ZF4 A;  1F7K A;  1PKJ A;  5EDD A;  2HXB A;  3TPW A;  1MQ7 A;  4LHR A;  1DUD A;  3TSL A;  3I93 A;  3TRN A;  2D4M A;  1PKK A;  4OOQ A;  3TQZ A;  4B0H A;  3SO2 A;  2R9Q A;  2ZDC A;  2XCE A;  5ECT A;  2HRM A;  1SM8 A;  2V9X A;  3KM3 A;  3C2T A;  3TPN A;  4AOZ A;  3ZF0 A;  3ZF2 A;  1EU5 A;  3TQ5 A;  3TTA A;  4XJC A;  3MDX A;  2OKD A;  2WE0 A;  3CA9 A;  4APZ 1;  2PY4 A;  2YZJ A;  3TQ3 A;  3ARN A;  2WE3 A;  1SYL A;  2J4H A;  2QXX A;  1F7N A;  1DUP A;  1OGH A;  2Y1T A;  2XY3 A;  1Q5H A;  3ARA A;  5CCO A;  2D4L A;  4AO5 A;  3LQW A;  2BAZ A;  4WRK A;  1F7R A;  3ZEZ A;  3GF0 A;  1Q5U X;  2OKB A;  2OL0 A;  2XX6 A;  1RNJ A;  1SEH A;  3T6Y A;  1SIX A;  1F7Q A;  1DUN A;  2OKE A;  3ECY A;  2HQU A;  2PC5 A;  3T70 A;  1SLH A;  1EUW A;  1SMC A;  3TQ4 A;  3ZF6 A;  3TPY A;  3ZF3 A;  2D4N A;  2OL1 A;  3T64 A;  1SNF A;  4GK6 A;  1RN8 A;  1F7D A;  3HZA A;  5F9K A;  3TRL A;  3ZF5 A;  1SJN A;  3TPS A;  3P48 A;  2HXD A;  2BT1 A; 
#chains in the Genus database with same CATH topology
 2QLP A;  4GCY A;  4DHK A;  3TS6 A;  1XS1 A;  1F7O A;  2HR6 A;  2WE2 A;  1DUC A;  3TP1 A;  2XCD A;  2Y8C A;  4GV8 A;  4A6A A;  2WE1 A;  1XS4 A;  2BSY A;  4OOP A;  3F4F A;  3H6D A;  1F7P A;  1DUT A;  3ZF1 A;  3T60 A;  3HHQ A;  3EHW A;  4AOO A;  2J4Q A;  3MBQ A;  1VYQ A;  3LOJ A;  5CCT A;  1PKH A;  3C3I A;  1XS6 A;  3H6X A;  3ZF4 A;  1F7K A;  1PKJ A;  5EDD A;  2HXB A;  3TPW A;  1MQ7 A;  4LHR A;  1DUD A;  3TSL A;  3I93 A;  3TRN A;  2D4M A;  1PKK A;  4OOQ A;  3TQZ A;  4B0H A;  3SO2 A;  2R9Q A;  2ZDC A;  2XCE A;  5ECT A;  2HRM A;  1SM8 A;  2V9X A;  3KM3 A;  3C2T A;  3TPN A;  4AOZ A;  3ZF0 A;  3ZF2 A;  1EU5 A;  3TQ5 A;  3TTA A;  4XJC A;  3MDX A;  2OKD A;  2WE0 A;  3CA9 A;  4APZ 1;  2PY4 A;  2YZJ A;  3TQ3 A;  3ARN A;  1TUL A;  2WE3 A;  1SYL A;  2J4H A;  2QXX A;  1F7N A;  1DUP A;  1OGH A;  2Y1T A;  2XY3 A;  1Q5H A;  3ARA A;  5CCO A;  2D4L A;  4AO5 A;  3LQW A;  2BAZ A;  4WRK A;  1F7R A;  3ZEZ A;  3GF0 A;  1Q5U X;  2OKB A;  2OL0 A;  2XX6 A;  1RNJ A;  1SEH A;  3T6Y A;  1SIX A;  1F7Q A;  1DUN A;  2OKE A;  3ECY A;  2HQU A;  2PC5 A;  3T70 A;  1SLH A;  1EUW A;  1SMC A;  3TQ4 A;  3ZF6 A;  3TPY A;  3ZF3 A;  2D4N A;  2OL1 A;  3T64 A;  1SNF A;  4GK6 A;  1RN8 A;  1F7D A;  3HZA A;  5F9K A;  3TRL A;  3ZF5 A;  1SJN A;  3TPS A;  3P48 A;  2HXD A;  2BT1 A; 
#chains in the Genus database with same CATH homology
 2QLP A;  4GCY A;  4DHK A;  3TS6 A;  1XS1 A;  1F7O A;  2HR6 A;  2WE2 A;  1DUC A;  3TP1 A;  2XCD A;  2Y8C A;  4GV8 A;  4A6A A;  2WE1 A;  1XS4 A;  2BSY A;  4OOP A;  3F4F A;  3H6D A;  1F7P A;  1DUT A;  3ZF1 A;  3T60 A;  3HHQ A;  3EHW A;  4AOO A;  2J4Q A;  3MBQ A;  1VYQ A;  3LOJ A;  5CCT A;  1PKH A;  3C3I A;  1XS6 A;  3H6X A;  3ZF4 A;  1F7K A;  1PKJ A;  5EDD A;  2HXB A;  3TPW A;  1MQ7 A;  4LHR A;  1DUD A;  3TSL A;  3I93 A;  3TRN A;  2D4M A;  1PKK A;  4OOQ A;  3TQZ A;  4B0H A;  3SO2 A;  2R9Q A;  2ZDC A;  2XCE A;  5ECT A;  2HRM A;  1SM8 A;  2V9X A;  3KM3 A;  3C2T A;  3TPN A;  4AOZ A;  3ZF0 A;  3ZF2 A;  1EU5 A;  3TQ5 A;  3TTA A;  4XJC A;  3MDX A;  2OKD A;  2WE0 A;  3CA9 A;  4APZ 1;  2PY4 A;  2YZJ A;  3TQ3 A;  3ARN A;  2WE3 A;  1SYL A;  2J4H A;  2QXX A;  1F7N A;  1DUP A;  1OGH A;  2Y1T A;  2XY3 A;  1Q5H A;  3ARA A;  5CCO A;  2D4L A;  4AO5 A;  3LQW A;  2BAZ A;  4WRK A;  1F7R A;  3ZEZ A;  3GF0 A;  1Q5U X;  2OKB A;  2OL0 A;  2XX6 A;  1RNJ A;  1SEH A;  3T6Y A;  1SIX A;  1F7Q A;  1DUN A;  2OKE A;  3ECY A;  2HQU A;  2PC5 A;  3T70 A;  1SLH A;  1EUW A;  1SMC A;  3TQ4 A;  3ZF6 A;  3TPY A;  3ZF3 A;  2D4N A;  2OL1 A;  3T64 A;  1SNF A;  4GK6 A;  1RN8 A;  1F7D A;  3HZA A;  5F9K A;  3TRL A;  3ZF5 A;  1SJN A;  3TPS A;  3P48 A;  2HXD A;  2BT1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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