2R2MA

2-(2-chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
26
structure length
26
Chain Sequence
ADCGLRPLFEKKSLEDKTERELLESY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Thrombin light chain
total genus 5
structure length 26
sequence length 26
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2007-08-27
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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