2WE0A

Ebv dutpase mutant cys4ser
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
252
structure length
247
Chain Sequence
PHIRYAFQNDKLLLQQASVGRLTLVNKTTILLRPMKTTTVDLGLYARPPEGHGLMLWGSTSRPVTSHVGIIDPGYTGELRLILQNQRRYNSTLRPSELKIHLAAFRYATPQGPINHPQYPGDVGLDVSLPKDLALFPHQTVSVTLTVPPPSIPHHRPTIFGRSGLAMQGILVKPCRWRRGGVDVSLTNFSDQTVFLNKYRRFCQLVYLHKHHLTSFYSPHSDAGVLGPRSLFRWASCTFEEVPSLAM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Flexible Motif V of Epstein-Barr Virus Deoxyuridine 5'-Triphosphate Pyrophosphatase is Essential for Catalysis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Human herpesvirus 4
molecule keywords DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE
total genus 41
structure length 247
sequence length 252
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2009-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 2we0A01
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 2we0A02
2QLPA 3TTAA 3LOJA 2D4MA 4AOOA 1F7QA 1DUDA 4LHRA 2ZDCA 1SJNA 1F7OA 4AO5A 1XS6A 3T64A 2WE2A 2PY4A 1PKHA 3TRLA 3ZF2A 1DUCA 5EDDA 3EHWA 5CCTA 3TPSA 1SM8A 4GK6A 2HXBA 3MDXA 3ZF5A 3H6DA 1XS4A 3HZAA 2WE3A 2OL0A 2HRMA 3T70A 3H6XA 3TQ4A 4WRKA 1F7DA 1Q5HA 5CCOA 3TS6A 3TPWA 3T60A 2XCDA 3ZF1A 3LQWA 1SEHA 3P48A 2BT1A 4GV8A 4B0HA 4XJCA 3SO2A 3ARNA 3T6YA 1Q5UX 1OGHA 2QXXA 1EU5A 2J4QA 3TRNA 1F7PA 1PKJA 1EUWA 2XCEA 1SIXA 4GCYA 3C3IA 3ZF4A 5F9KA 2D4LA 3TQZA 2HQUA 3ZEZA 2BAZA 2J4HA 2PC5A 3ZF0A 2HR6A 3F4FA 3GF0A 3C2TA 1DUNA 3TSLA 2Y8CA 2XY3A 4DHKA 1MQ7A 3ZF3A 3TPYA 2YZJA 3ZF6A 1F7KA 2WE1A 3ARAA 4OOQA 2BSYA 2D4NA 1RN8A 2OL1A 1XS1A 1VYQA 3MBQA 1SLHA 3TQ3A 2V9XA 1SMCA 3I93A 2XX6A 2OKBA 3TQ5A 4AOZA 2WE0A 1DUTA 1DUPA 4A6AA 2Y1TA 3HHQA 3TPNA 1SYLA 1RNJA 2HXDA 2OKDA 2R9QA 3KM3A 1PKKA 4APZ1 5ECTA 1F7NA 1F7RA 3CA9A 3TP1A 1SNFA 4OOPA 3ECYA 2OKEA
chains in the Genus database with same CATH superfamily
2QLPA 3TTAA 3LOJA 2D4MA 4AOOA 1F7QA 1DUDA 4LHRA 2ZDCA 1SJNA 1F7OA 4AO5A 1XS6A 3T64A 2WE2A 2PY4A 1PKHA 3TRLA 3ZF2A 1DUCA 5EDDA 3EHWA 5CCTA 3TPSA 1SM8A 4GK6A 2HXBA 3MDXA 3ZF5A 3H6DA 1XS4A 3HZAA 2WE3A 2OL0A 2HRMA 3T70A 3H6XA 3TQ4A 4WRKA 1F7DA 1Q5HA 5CCOA 3TS6A 3TPWA 3T60A 2XCDA 3ZF1A 3LQWA 1SEHA 3P48A 2BT1A 4GV8A 4B0HA 4XJCA 3SO2A 3ARNA 3T6YA 1Q5UX 1OGHA 2QXXA 1EU5A 2J4QA 3TRNA 1TULA 1F7PA 1PKJA 1EUWA 2XCEA 1SIXA 4GCYA 3C3IA 3ZF4A 5F9KA 2D4LA 3TQZA 2HQUA 3ZEZA 2BAZA 2J4HA 2PC5A 3ZF0A 2HR6A 3F4FA 3GF0A 3C2TA 1DUNA 3TSLA 2Y8CA 2XY3A 4DHKA 1MQ7A 3ZF3A 3TPYA 2YZJA 3ZF6A 1F7KA 2WE1A 3ARAA 4OOQA 2BSYA 2D4NA 1RN8A 2OL1A 1XS1A 1VYQA 3MBQA 1SLHA 3TQ3A 2V9XA 1SMCA 3I93A 2XX6A 2OKBA 3TQ5A 4AOZA 2WE0A 1DUTA 1DUPA 4A6AA 2Y1TA 3HHQA 3TPNA 1SYLA 1RNJA 2HXDA 2OKDA 2R9QA 3KM3A 1PKKA 4APZ1 5ECTA 1F7NA 1F7RA 3CA9A 3TP1A 1SNFA 4OOPA 3ECYA 2OKEA
chains in the Genus database with same CATH topology
2QLPA 3TTAA 3LOJA 2D4MA 4AOOA 1F7QA 1DUDA 4LHRA 2ZDCA 1SJNA 1F7OA 4AO5A 1XS6A 3T64A 2WE2A 2PY4A 1PKHA 3TRLA 3ZF2A 1DUCA 5EDDA 3EHWA 5CCTA 3TPSA 1SM8A 4GK6A 2HXBA 3MDXA 3ZF5A 3H6DA 1XS4A 3HZAA 2WE3A 2OL0A 2HRMA 3T70A 3H6XA 3TQ4A 4WRKA 1F7DA 1Q5HA 5CCOA 3TS6A 3TPWA 3T60A 2XCDA 3ZF1A 3LQWA 1SEHA 3P48A 2BT1A 4GV8A 4B0HA 4XJCA 3SO2A 3ARNA 3T6YA 1Q5UX 1OGHA 2QXXA 1EU5A 2J4QA 3TRNA 1F7PA 1PKJA 1EUWA 2XCEA 1SIXA 4GCYA 3C3IA 3ZF4A 5F9KA 2D4LA 3TQZA 2HQUA 3ZEZA 2BAZA 2J4HA 2PC5A 3ZF0A 2HR6A 3F4FA 3GF0A 3C2TA 1DUNA 3TSLA 2Y8CA 2XY3A 4DHKA 1MQ7A 3ZF3A 3TPYA 2YZJA 3ZF6A 1F7KA 2WE1A 3ARAA 4OOQA 2BSYA 2D4NA 1RN8A 2OL1A 1XS1A 1VYQA 3MBQA 1SLHA 3TQ3A 2V9XA 1SMCA 3I93A 2XX6A 2OKBA 3TQ5A 4AOZA 2WE0A 1DUTA 1DUPA 4A6AA 2Y1TA 3HHQA 3TPNA 1SYLA 1RNJA 2HXDA 2OKDA 2R9QA 3KM3A 1PKKA 4APZ1 5ECTA 1F7NA 1F7RA 3CA9A 3TP1A 1SNFA 4OOPA 3ECYA 2OKEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QLP A;  3TTA A;  3LOJ A;  2D4M A;  4AOO A;  1F7Q A;  1DUD A;  4LHR A;  2ZDC A;  1SJN A;  1F7O A;  4AO5 A;  1XS6 A;  3T64 A;  2WE2 A;  2PY4 A;  1PKH A;  3TRL A;  3ZF2 A;  1DUC A;  5EDD A;  3EHW A;  5CCT A;  3TPS A;  1SM8 A;  4GK6 A;  2HXB A;  3MDX A;  3ZF5 A;  3H6D A;  1XS4 A;  3HZA A;  2WE3 A;  2OL0 A;  2HRM A;  3T70 A;  3H6X A;  3TQ4 A;  4WRK A;  1F7D A;  1Q5H A;  5CCO A;  3TS6 A;  3TPW A;  3T60 A;  2XCD A;  3ZF1 A;  3LQW A;  1SEH A;  3P48 A;  2BT1 A;  4GV8 A;  4B0H A;  4XJC A;  3SO2 A;  3ARN A;  3T6Y A;  1Q5U X;  1OGH A;  2QXX A;  1EU5 A;  2J4Q A;  3TRN A;  1F7P A;  1PKJ A;  1EUW A;  2XCE A;  1SIX A;  4GCY A;  3C3I A;  3ZF4 A;  5F9K A;  2D4L A;  3TQZ A;  2HQU A;  3ZEZ A;  2BAZ A;  2J4H A;  2PC5 A;  3ZF0 A;  2HR6 A;  3F4F A;  3GF0 A;  3C2T A;  1DUN A;  3TSL A;  2Y8C A;  2XY3 A;  4DHK A;  1MQ7 A;  3ZF3 A;  3TPY A;  2YZJ A;  3ZF6 A;  1F7K A;  2WE1 A;  3ARA A;  4OOQ A;  2BSY A;  2D4N A;  1RN8 A;  2OL1 A;  1XS1 A;  1VYQ A;  3MBQ A;  1SLH A;  3TQ3 A;  2V9X A;  1SMC A;  3I93 A;  2XX6 A;  2OKB A;  3TQ5 A;  4AOZ A;  2WE0 A;  1DUT A;  1DUP A;  4A6A A;  2Y1T A;  3HHQ A;  3TPN A;  1SYL A;  1RNJ A;  2HXD A;  2OKD A;  2R9Q A;  3KM3 A;  1PKK A;  4APZ 1;  5ECT A;  1F7N A;  1F7R A;  3CA9 A;  3TP1 A;  1SNF A;  4OOP A;  3ECY A;  2OKE A; 
#chains in the Genus database with same CATH topology
 2QLP A;  3TTA A;  3LOJ A;  2D4M A;  4AOO A;  1F7Q A;  1DUD A;  4LHR A;  2ZDC A;  1SJN A;  1F7O A;  4AO5 A;  1XS6 A;  3T64 A;  2WE2 A;  2PY4 A;  1PKH A;  3TRL A;  3ZF2 A;  1DUC A;  5EDD A;  3EHW A;  5CCT A;  3TPS A;  1SM8 A;  4GK6 A;  2HXB A;  3MDX A;  3ZF5 A;  3H6D A;  1XS4 A;  3HZA A;  2WE3 A;  2OL0 A;  2HRM A;  3T70 A;  3H6X A;  3TQ4 A;  4WRK A;  1F7D A;  1Q5H A;  5CCO A;  3TS6 A;  3TPW A;  3T60 A;  2XCD A;  3ZF1 A;  3LQW A;  1SEH A;  3P48 A;  2BT1 A;  4GV8 A;  4B0H A;  4XJC A;  3SO2 A;  3ARN A;  3T6Y A;  1Q5U X;  1OGH A;  2QXX A;  1EU5 A;  2J4Q A;  3TRN A;  1TUL A;  1F7P A;  1PKJ A;  1EUW A;  2XCE A;  1SIX A;  4GCY A;  3C3I A;  3ZF4 A;  5F9K A;  2D4L A;  3TQZ A;  2HQU A;  3ZEZ A;  2BAZ A;  2J4H A;  2PC5 A;  3ZF0 A;  2HR6 A;  3F4F A;  3GF0 A;  3C2T A;  1DUN A;  3TSL A;  2Y8C A;  2XY3 A;  4DHK A;  1MQ7 A;  3ZF3 A;  3TPY A;  2YZJ A;  3ZF6 A;  1F7K A;  2WE1 A;  3ARA A;  4OOQ A;  2BSY A;  2D4N A;  1RN8 A;  2OL1 A;  1XS1 A;  1VYQ A;  3MBQ A;  1SLH A;  3TQ3 A;  2V9X A;  1SMC A;  3I93 A;  2XX6 A;  2OKB A;  3TQ5 A;  4AOZ A;  2WE0 A;  1DUT A;  1DUP A;  4A6A A;  2Y1T A;  3HHQ A;  3TPN A;  1SYL A;  1RNJ A;  2HXD A;  2OKD A;  2R9Q A;  3KM3 A;  1PKK A;  4APZ 1;  5ECT A;  1F7N A;  1F7R A;  3CA9 A;  3TP1 A;  1SNF A;  4OOP A;  3ECY A;  2OKE A; 
#chains in the Genus database with same CATH homology
 2QLP A;  3TTA A;  3LOJ A;  2D4M A;  4AOO A;  1F7Q A;  1DUD A;  4LHR A;  2ZDC A;  1SJN A;  1F7O A;  4AO5 A;  1XS6 A;  3T64 A;  2WE2 A;  2PY4 A;  1PKH A;  3TRL A;  3ZF2 A;  1DUC A;  5EDD A;  3EHW A;  5CCT A;  3TPS A;  1SM8 A;  4GK6 A;  2HXB A;  3MDX A;  3ZF5 A;  3H6D A;  1XS4 A;  3HZA A;  2WE3 A;  2OL0 A;  2HRM A;  3T70 A;  3H6X A;  3TQ4 A;  4WRK A;  1F7D A;  1Q5H A;  5CCO A;  3TS6 A;  3TPW A;  3T60 A;  2XCD A;  3ZF1 A;  3LQW A;  1SEH A;  3P48 A;  2BT1 A;  4GV8 A;  4B0H A;  4XJC A;  3SO2 A;  3ARN A;  3T6Y A;  1Q5U X;  1OGH A;  2QXX A;  1EU5 A;  2J4Q A;  3TRN A;  1F7P A;  1PKJ A;  1EUW A;  2XCE A;  1SIX A;  4GCY A;  3C3I A;  3ZF4 A;  5F9K A;  2D4L A;  3TQZ A;  2HQU A;  3ZEZ A;  2BAZ A;  2J4H A;  2PC5 A;  3ZF0 A;  2HR6 A;  3F4F A;  3GF0 A;  3C2T A;  1DUN A;  3TSL A;  2Y8C A;  2XY3 A;  4DHK A;  1MQ7 A;  3ZF3 A;  3TPY A;  2YZJ A;  3ZF6 A;  1F7K A;  2WE1 A;  3ARA A;  4OOQ A;  2BSY A;  2D4N A;  1RN8 A;  2OL1 A;  1XS1 A;  1VYQ A;  3MBQ A;  1SLH A;  3TQ3 A;  2V9X A;  1SMC A;  3I93 A;  2XX6 A;  2OKB A;  3TQ5 A;  4AOZ A;  2WE0 A;  1DUT A;  1DUP A;  4A6A A;  2Y1T A;  3HHQ A;  3TPN A;  1SYL A;  1RNJ A;  2HXD A;  2OKD A;  2R9Q A;  3KM3 A;  1PKK A;  4APZ 1;  5ECT A;  1F7N A;  1F7R A;  3CA9 A;  3TP1 A;  1SNF A;  4OOP A;  3ECY A;  2OKE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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