2WE1A

Ebv dutpase mutant asp131asn with bound dump
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
253
structure length
245
Chain Sequence
CPHIRYAFQNDKLLLQQASVGRLTLVNKTTILLRPMKTTTVDLGLYARPPEGHGLMLWGSTSRPVTSHVGIIDPGYTGELRLILQNQRRYNSTLRPSELKIHLAAFRYATPQMGPINPGNVGLDVSLPKDLALFPHQTVSVTLTVPPPSIPHHRPTIFGRSGLAMQGILVKPCRWRRGGVDVSLTNFSDQTVFLNKYRRFCQLVYLHKHHLTSFYSPHSDAGVLGPRSLFRWASCTFEEVPSLAM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Flexible Motif V of Epstein-Barr Virus Deoxyuridine 5'-Triphosphate Pyrophosphatase is Essential for Catalysis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Human herpesvirus 4
molecule keywords DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE
total genus 41
structure length 245
sequence length 253
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2009-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 2we1A01
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 2we1A02
3T6YA 3TS6A 1SIXA 2J4HA 3LQWA 2BT1A 3HZAA 1PKKA 2HXDA 2ZDCA 1EU5A 2J4QA 3I93A 1F7NA 3TP1A 3ECYA 1DUCA 3F4FA 3ZF3A 2BAZA 1DUPA 2D4NA 1SLHA 2WE3A 1SNFA 2HR6A 3LOJA 3MDXA 3T64A 1DUTA 4GV8A 3SO2A 5F9KA 4AOOA 4B0HA 1OGHA 1XS4A 2V9XA 1SMCA 3TQ5A 3ARNA 2OKBA 2OKDA 2D4MA 2XCEA 3C2TA 2PC5A 1MQ7A 3TPYA 3EHWA 3TPNA 2WE0A 3MBQA 1VYQA 3ZF6A 4DHKA 1RNJA 4OOQA 3TPSA 3TSLA 4AOZA 3P48A 2WE2A 1DUDA 2QXXA 3TRLA 3T70A 3TRNA 3TTAA 1DUNA 1SYLA 4AO5A 1F7RA 3ZF4A 3C3IA 4XJCA 2OL1A 2BSYA 2HQUA 1EUWA 2Y8CA 5CCOA 4GK6A 4GCYA 1F7QA 1SM8A 3ZEZA 2D4LA 2OKEA 1XS1A 2HXBA 1PKJA 2Y1TA 3ZF1A 3HHQA 1Q5HA 2XY3A 1XS6A 3ZF0A 2PY4A 2WE1A 3TQZA 1PKHA 3KM3A 3GF0A 3TQ3A 2OL0A 2HRMA 3ARAA 5EDDA 4LHRA 3TQ4A 1F7PA 1SJNA 4OOPA 2YZJA 1Q5UX 1RN8A 3H6DA 1F7KA 1SEHA 5ECTA 3TPWA 3CA9A 3T60A 2QLPA 3ZF5A 2R9QA 4A6AA 4WRKA 2XX6A 2XCDA 3ZF2A 3H6XA 4APZ1 1F7OA 5CCTA 1F7DA
chains in the Genus database with same CATH superfamily
3T6YA 3TS6A 1SIXA 2J4HA 3LQWA 2BT1A 3HZAA 1PKKA 2HXDA 2ZDCA 1EU5A 2J4QA 3I93A 1F7NA 3TP1A 3ECYA 1DUCA 3F4FA 3ZF3A 2BAZA 1DUPA 2D4NA 1SLHA 2WE3A 1SNFA 2HR6A 1TULA 3LOJA 3MDXA 3T64A 1DUTA 4GV8A 3SO2A 5F9KA 4AOOA 4B0HA 1OGHA 1XS4A 2V9XA 1SMCA 3TQ5A 3ARNA 2OKBA 2OKDA 2D4MA 2XCEA 3C2TA 2PC5A 1MQ7A 3TPYA 3EHWA 3TPNA 2WE0A 3MBQA 1VYQA 3ZF6A 4DHKA 1RNJA 4OOQA 3TPSA 3TSLA 4AOZA 3P48A 2WE2A 1DUDA 2QXXA 3TRLA 3T70A 3TRNA 3TTAA 1DUNA 1SYLA 4AO5A 1F7RA 3ZF4A 3C3IA 4XJCA 2OL1A 2BSYA 2HQUA 1EUWA 2Y8CA 5CCOA 4GK6A 4GCYA 1F7QA 1SM8A 3ZEZA 2D4LA 2OKEA 1XS1A 2HXBA 1PKJA 2Y1TA 3ZF1A 3HHQA 1Q5HA 2XY3A 1XS6A 3ZF0A 2PY4A 2WE1A 3TQZA 1PKHA 3KM3A 3GF0A 3TQ3A 2OL0A 2HRMA 3ARAA 5EDDA 4LHRA 3TQ4A 1F7PA 1SJNA 4OOPA 2YZJA 1Q5UX 1RN8A 3H6DA 1F7KA 1SEHA 5ECTA 3TPWA 3CA9A 3T60A 2QLPA 3ZF5A 2R9QA 4A6AA 4WRKA 2XX6A 2XCDA 3ZF2A 3H6XA 4APZ1 1F7OA 5CCTA 1F7DA
chains in the Genus database with same CATH topology
3T6YA 3TS6A 1SIXA 2J4HA 3LQWA 2BT1A 3HZAA 1PKKA 2HXDA 2ZDCA 1EU5A 2J4QA 3I93A 1F7NA 3TP1A 3ECYA 1DUCA 3F4FA 3ZF3A 2BAZA 1DUPA 2D4NA 1SLHA 2WE3A 1SNFA 2HR6A 3LOJA 3MDXA 3T64A 1DUTA 4GV8A 3SO2A 5F9KA 4AOOA 4B0HA 1OGHA 1XS4A 2V9XA 1SMCA 3TQ5A 3ARNA 2OKBA 2OKDA 2D4MA 2XCEA 3C2TA 2PC5A 1MQ7A 3TPYA 3EHWA 3TPNA 2WE0A 3MBQA 1VYQA 3ZF6A 4DHKA 1RNJA 4OOQA 3TPSA 3TSLA 4AOZA 3P48A 2WE2A 1DUDA 2QXXA 3TRLA 3T70A 3TRNA 3TTAA 1DUNA 1SYLA 4AO5A 1F7RA 3ZF4A 3C3IA 4XJCA 2OL1A 2BSYA 2HQUA 1EUWA 2Y8CA 5CCOA 4GK6A 4GCYA 1F7QA 1SM8A 3ZEZA 2D4LA 2OKEA 1XS1A 2HXBA 1PKJA 2Y1TA 3ZF1A 3HHQA 1Q5HA 2XY3A 1XS6A 3ZF0A 2PY4A 2WE1A 3TQZA 1PKHA 3KM3A 3GF0A 3TQ3A 2OL0A 2HRMA 3ARAA 5EDDA 4LHRA 3TQ4A 1F7PA 1SJNA 4OOPA 2YZJA 1Q5UX 1RN8A 3H6DA 1F7KA 1SEHA 5ECTA 3TPWA 3CA9A 3T60A 2QLPA 3ZF5A 2R9QA 4A6AA 4WRKA 2XX6A 2XCDA 3ZF2A 3H6XA 4APZ1 1F7OA 5CCTA 1F7DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T6Y A;  3TS6 A;  1SIX A;  2J4H A;  3LQW A;  2BT1 A;  3HZA A;  1PKK A;  2HXD A;  2ZDC A;  1EU5 A;  2J4Q A;  3I93 A;  1F7N A;  3TP1 A;  3ECY A;  1DUC A;  3F4F A;  3ZF3 A;  2BAZ A;  1DUP A;  2D4N A;  1SLH A;  2WE3 A;  1SNF A;  2HR6 A;  3LOJ A;  3MDX A;  3T64 A;  1DUT A;  4GV8 A;  3SO2 A;  5F9K A;  4AOO A;  4B0H A;  1OGH A;  1XS4 A;  2V9X A;  1SMC A;  3TQ5 A;  3ARN A;  2OKB A;  2OKD A;  2D4M A;  2XCE A;  3C2T A;  2PC5 A;  1MQ7 A;  3TPY A;  3EHW A;  3TPN A;  2WE0 A;  3MBQ A;  1VYQ A;  3ZF6 A;  4DHK A;  1RNJ A;  4OOQ A;  3TPS A;  3TSL A;  4AOZ A;  3P48 A;  2WE2 A;  1DUD A;  2QXX A;  3TRL A;  3T70 A;  3TRN A;  3TTA A;  1DUN A;  1SYL A;  4AO5 A;  1F7R A;  3ZF4 A;  3C3I A;  4XJC A;  2OL1 A;  2BSY A;  2HQU A;  1EUW A;  2Y8C A;  5CCO A;  4GK6 A;  4GCY A;  1F7Q A;  1SM8 A;  3ZEZ A;  2D4L A;  2OKE A;  1XS1 A;  2HXB A;  1PKJ A;  2Y1T A;  3ZF1 A;  3HHQ A;  1Q5H A;  2XY3 A;  1XS6 A;  3ZF0 A;  2PY4 A;  2WE1 A;  3TQZ A;  1PKH A;  3KM3 A;  3GF0 A;  3TQ3 A;  2OL0 A;  2HRM A;  3ARA A;  5EDD A;  4LHR A;  3TQ4 A;  1F7P A;  1SJN A;  4OOP A;  2YZJ A;  1Q5U X;  1RN8 A;  3H6D A;  1F7K A;  1SEH A;  5ECT A;  3TPW A;  3CA9 A;  3T60 A;  2QLP A;  3ZF5 A;  2R9Q A;  4A6A A;  4WRK A;  2XX6 A;  2XCD A;  3ZF2 A;  3H6X A;  4APZ 1;  1F7O A;  5CCT A;  1F7D A; 
#chains in the Genus database with same CATH topology
 3T6Y A;  3TS6 A;  1SIX A;  2J4H A;  3LQW A;  2BT1 A;  3HZA A;  1PKK A;  2HXD A;  2ZDC A;  1EU5 A;  2J4Q A;  3I93 A;  1F7N A;  3TP1 A;  3ECY A;  1DUC A;  3F4F A;  3ZF3 A;  2BAZ A;  1DUP A;  2D4N A;  1SLH A;  2WE3 A;  1SNF A;  2HR6 A;  1TUL A;  3LOJ A;  3MDX A;  3T64 A;  1DUT A;  4GV8 A;  3SO2 A;  5F9K A;  4AOO A;  4B0H A;  1OGH A;  1XS4 A;  2V9X A;  1SMC A;  3TQ5 A;  3ARN A;  2OKB A;  2OKD A;  2D4M A;  2XCE A;  3C2T A;  2PC5 A;  1MQ7 A;  3TPY A;  3EHW A;  3TPN A;  2WE0 A;  3MBQ A;  1VYQ A;  3ZF6 A;  4DHK A;  1RNJ A;  4OOQ A;  3TPS A;  3TSL A;  4AOZ A;  3P48 A;  2WE2 A;  1DUD A;  2QXX A;  3TRL A;  3T70 A;  3TRN A;  3TTA A;  1DUN A;  1SYL A;  4AO5 A;  1F7R A;  3ZF4 A;  3C3I A;  4XJC A;  2OL1 A;  2BSY A;  2HQU A;  1EUW A;  2Y8C A;  5CCO A;  4GK6 A;  4GCY A;  1F7Q A;  1SM8 A;  3ZEZ A;  2D4L A;  2OKE A;  1XS1 A;  2HXB A;  1PKJ A;  2Y1T A;  3ZF1 A;  3HHQ A;  1Q5H A;  2XY3 A;  1XS6 A;  3ZF0 A;  2PY4 A;  2WE1 A;  3TQZ A;  1PKH A;  3KM3 A;  3GF0 A;  3TQ3 A;  2OL0 A;  2HRM A;  3ARA A;  5EDD A;  4LHR A;  3TQ4 A;  1F7P A;  1SJN A;  4OOP A;  2YZJ A;  1Q5U X;  1RN8 A;  3H6D A;  1F7K A;  1SEH A;  5ECT A;  3TPW A;  3CA9 A;  3T60 A;  2QLP A;  3ZF5 A;  2R9Q A;  4A6A A;  4WRK A;  2XX6 A;  2XCD A;  3ZF2 A;  3H6X A;  4APZ 1;  1F7O A;  5CCT A;  1F7D A; 
#chains in the Genus database with same CATH homology
 3T6Y A;  3TS6 A;  1SIX A;  2J4H A;  3LQW A;  2BT1 A;  3HZA A;  1PKK A;  2HXD A;  2ZDC A;  1EU5 A;  2J4Q A;  3I93 A;  1F7N A;  3TP1 A;  3ECY A;  1DUC A;  3F4F A;  3ZF3 A;  2BAZ A;  1DUP A;  2D4N A;  1SLH A;  2WE3 A;  1SNF A;  2HR6 A;  3LOJ A;  3MDX A;  3T64 A;  1DUT A;  4GV8 A;  3SO2 A;  5F9K A;  4AOO A;  4B0H A;  1OGH A;  1XS4 A;  2V9X A;  1SMC A;  3TQ5 A;  3ARN A;  2OKB A;  2OKD A;  2D4M A;  2XCE A;  3C2T A;  2PC5 A;  1MQ7 A;  3TPY A;  3EHW A;  3TPN A;  2WE0 A;  3MBQ A;  1VYQ A;  3ZF6 A;  4DHK A;  1RNJ A;  4OOQ A;  3TPS A;  3TSL A;  4AOZ A;  3P48 A;  2WE2 A;  1DUD A;  2QXX A;  3TRL A;  3T70 A;  3TRN A;  3TTA A;  1DUN A;  1SYL A;  4AO5 A;  1F7R A;  3ZF4 A;  3C3I A;  4XJC A;  2OL1 A;  2BSY A;  2HQU A;  1EUW A;  2Y8C A;  5CCO A;  4GK6 A;  4GCY A;  1F7Q A;  1SM8 A;  3ZEZ A;  2D4L A;  2OKE A;  1XS1 A;  2HXB A;  1PKJ A;  2Y1T A;  3ZF1 A;  3HHQ A;  1Q5H A;  2XY3 A;  1XS6 A;  3ZF0 A;  2PY4 A;  2WE1 A;  3TQZ A;  1PKH A;  3KM3 A;  3GF0 A;  3TQ3 A;  2OL0 A;  2HRM A;  3ARA A;  5EDD A;  4LHR A;  3TQ4 A;  1F7P A;  1SJN A;  4OOP A;  2YZJ A;  1Q5U X;  1RN8 A;  3H6D A;  1F7K A;  1SEH A;  5ECT A;  3TPW A;  3CA9 A;  3T60 A;  2QLP A;  3ZF5 A;  2R9Q A;  4A6A A;  4WRK A;  2XX6 A;  2XCD A;  3ZF2 A;  3H6X A;  4APZ 1;  1F7O A;  5CCT A;  1F7D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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