2WE2A

Ebv dutpase double mutant gly78asp-asp131ser with dump
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
253
structure length
248
Chain Sequence
CPHIRYAFQNDKLLLQQASVGRLTLVNKTTILLRPMKTTTVDLGLYARPPEGHGLMLWGSTSRPVTSHVGIIDPDYTGELRLILQNQRRYNSTLRPSELKIHLAAFRYATPQGPINHPQYPGSVGLDVSLPKDLALFPHQTVSVTLTVPPPSIPHHRPTIFGRSGLAMQGILVKPCRWRRGGVDVSLTNFSDQTVFLNKYRRFCQLVYLHKHHLTSFYSPHSDAGVLGPRSLFRWASCTFEEVPSLAM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Flexible Motif V of Epstein-Barr Virus Deoxyuridine 5'-Triphosphate Pyrophosphatase is Essential for Catalysis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Human herpesvirus 4
molecule keywords DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE
total genus 42
structure length 248
sequence length 253
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2009-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 2we2A01
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 2we2A02
2BSYA 1PKJA 3TQ4A 1F7QA 2OKEA 1F7RA 1RN8A 1SIXA 2OL1A 3MDXA 4B0HA 3ARNA 2XY3A 2D4MA 4OOQA 3TQ5A 1DUPA 1DUCA 3ECYA 2D4NA 3I93A 4GK6A 3ZEZA 3LOJA 3C3IA 2HRMA 2HQUA 2HR6A 3TS6A 1F7OA 3EHWA 4AOOA 1SNFA 3TRNA 3ZF5A 3MBQA 4AO5A 4XJCA 3H6DA 4WRKA 4APZ1 3KM3A 1SM8A 1MQ7A 3H6XA 1SJNA 1PKKA 3TQZA 3T70A 1XS1A 5CCTA 5EDDA 2QLPA 4LHRA 2ZDCA 3HZAA 5ECTA 3TTAA 3ZF6A 4DHKA 3T60A 2HXBA 2J4HA 3TSLA 3TRLA 3CA9A 1PKHA 2D4LA 3C2TA 3SO2A 2WE2A 4GCYA 3ZF3A 5CCOA 3TQ3A 3TPWA 3GF0A 2Y8CA 2BAZA 3T64A 3ZF4A 3ZF0A 1SYLA 3HHQA 1Q5UX 4OOPA 3P48A 1F7DA 2OL0A 1F7NA 2WE3A 2Y1TA 2QXXA 1SEHA 2PC5A 1XS4A 2R9QA 1EUWA 1F7KA 3TPNA 1VYQA 5F9KA 2J4QA 1SLHA 1XS6A 2YZJA 2V9XA 2XCDA 3TPYA 2XX6A 2XCEA 3ZF1A 3TP1A 1Q5HA 2BT1A 3TPSA 3T6YA 1SMCA 3F4FA 2WE1A 1DUTA 2OKDA 4AOZA 2WE0A 1DUDA 2PY4A 3ARAA 1F7PA 1DUNA 3ZF2A 2HXDA 3LQWA 4A6AA 1OGHA 1EU5A 2OKBA 4GV8A 1RNJA
chains in the Genus database with same CATH superfamily
2BSYA 1PKJA 3TQ4A 1F7QA 2OKEA 1F7RA 1RN8A 1SIXA 2OL1A 3MDXA 4B0HA 3ARNA 2XY3A 2D4MA 4OOQA 3TQ5A 1DUPA 1DUCA 3ECYA 2D4NA 3I93A 4GK6A 3ZEZA 3LOJA 3C3IA 2HRMA 2HQUA 2HR6A 3TS6A 1F7OA 3EHWA 4AOOA 1SNFA 3TRNA 3ZF5A 3MBQA 4AO5A 4XJCA 3H6DA 4WRKA 4APZ1 3KM3A 1SM8A 1MQ7A 3H6XA 1SJNA 1PKKA 3TQZA 3T70A 1XS1A 5CCTA 5EDDA 2QLPA 4LHRA 2ZDCA 3HZAA 5ECTA 3TTAA 3ZF6A 4DHKA 3T60A 2HXBA 2J4HA 3TSLA 3TRLA 3CA9A 1PKHA 2D4LA 3C2TA 3SO2A 2WE2A 4GCYA 3ZF3A 5CCOA 3TQ3A 3TPWA 3GF0A 2Y8CA 2BAZA 3T64A 3ZF4A 3ZF0A 1SYLA 3HHQA 1Q5UX 4OOPA 3P48A 1F7DA 2OL0A 1F7NA 2WE3A 2Y1TA 2QXXA 1SEHA 2PC5A 1XS4A 2R9QA 1EUWA 1F7KA 3TPNA 1VYQA 5F9KA 2J4QA 1SLHA 1XS6A 2YZJA 1TULA 2V9XA 2XCDA 3TPYA 2XX6A 2XCEA 3ZF1A 3TP1A 1Q5HA 2BT1A 3TPSA 3T6YA 1SMCA 3F4FA 2WE1A 1DUTA 2OKDA 4AOZA 2WE0A 1DUDA 2PY4A 3ARAA 1F7PA 1DUNA 3ZF2A 2HXDA 3LQWA 4A6AA 1OGHA 1EU5A 2OKBA 4GV8A 1RNJA
chains in the Genus database with same CATH topology
2BSYA 1PKJA 3TQ4A 1F7QA 2OKEA 1F7RA 1RN8A 1SIXA 2OL1A 3MDXA 4B0HA 3ARNA 2XY3A 2D4MA 4OOQA 3TQ5A 1DUPA 1DUCA 3ECYA 2D4NA 3I93A 4GK6A 3ZEZA 3LOJA 3C3IA 2HRMA 2HQUA 2HR6A 3TS6A 1F7OA 3EHWA 4AOOA 1SNFA 3TRNA 3ZF5A 3MBQA 4AO5A 4XJCA 3H6DA 4WRKA 4APZ1 3KM3A 1SM8A 1MQ7A 3H6XA 1SJNA 1PKKA 3TQZA 3T70A 1XS1A 5CCTA 5EDDA 2QLPA 4LHRA 2ZDCA 3HZAA 5ECTA 3TTAA 3ZF6A 4DHKA 3T60A 2HXBA 2J4HA 3TSLA 3TRLA 3CA9A 1PKHA 2D4LA 3C2TA 3SO2A 2WE2A 4GCYA 3ZF3A 5CCOA 3TQ3A 3TPWA 3GF0A 2Y8CA 2BAZA 3T64A 3ZF4A 3ZF0A 1SYLA 3HHQA 1Q5UX 4OOPA 3P48A 1F7DA 2OL0A 1F7NA 2WE3A 2Y1TA 2QXXA 1SEHA 2PC5A 1XS4A 2R9QA 1EUWA 1F7KA 3TPNA 1VYQA 5F9KA 2J4QA 1SLHA 1XS6A 2YZJA 2V9XA 2XCDA 3TPYA 2XX6A 2XCEA 3ZF1A 3TP1A 1Q5HA 2BT1A 3TPSA 3T6YA 1SMCA 3F4FA 2WE1A 1DUTA 2OKDA 4AOZA 2WE0A 1DUDA 2PY4A 3ARAA 1F7PA 1DUNA 3ZF2A 2HXDA 3LQWA 4A6AA 1OGHA 1EU5A 2OKBA 4GV8A 1RNJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BSY A;  1PKJ A;  3TQ4 A;  1F7Q A;  2OKE A;  1F7R A;  1RN8 A;  1SIX A;  2OL1 A;  3MDX A;  4B0H A;  3ARN A;  2XY3 A;  2D4M A;  4OOQ A;  3TQ5 A;  1DUP A;  1DUC A;  3ECY A;  2D4N A;  3I93 A;  4GK6 A;  3ZEZ A;  3LOJ A;  3C3I A;  2HRM A;  2HQU A;  2HR6 A;  3TS6 A;  1F7O A;  3EHW A;  4AOO A;  1SNF A;  3TRN A;  3ZF5 A;  3MBQ A;  4AO5 A;  4XJC A;  3H6D A;  4WRK A;  4APZ 1;  3KM3 A;  1SM8 A;  1MQ7 A;  3H6X A;  1SJN A;  1PKK A;  3TQZ A;  3T70 A;  1XS1 A;  5CCT A;  5EDD A;  2QLP A;  4LHR A;  2ZDC A;  3HZA A;  5ECT A;  3TTA A;  3ZF6 A;  4DHK A;  3T60 A;  2HXB A;  2J4H A;  3TSL A;  3TRL A;  3CA9 A;  1PKH A;  2D4L A;  3C2T A;  3SO2 A;  2WE2 A;  4GCY A;  3ZF3 A;  5CCO A;  3TQ3 A;  3TPW A;  3GF0 A;  2Y8C A;  2BAZ A;  3T64 A;  3ZF4 A;  3ZF0 A;  1SYL A;  3HHQ A;  1Q5U X;  4OOP A;  3P48 A;  1F7D A;  2OL0 A;  1F7N A;  2WE3 A;  2Y1T A;  2QXX A;  1SEH A;  2PC5 A;  1XS4 A;  2R9Q A;  1EUW A;  1F7K A;  3TPN A;  1VYQ A;  5F9K A;  2J4Q A;  1SLH A;  1XS6 A;  2YZJ A;  2V9X A;  2XCD A;  3TPY A;  2XX6 A;  2XCE A;  3ZF1 A;  3TP1 A;  1Q5H A;  2BT1 A;  3TPS A;  3T6Y A;  1SMC A;  3F4F A;  2WE1 A;  1DUT A;  2OKD A;  4AOZ A;  2WE0 A;  1DUD A;  2PY4 A;  3ARA A;  1F7P A;  1DUN A;  3ZF2 A;  2HXD A;  3LQW A;  4A6A A;  1OGH A;  1EU5 A;  2OKB A;  4GV8 A;  1RNJ A; 
#chains in the Genus database with same CATH topology
 2BSY A;  1PKJ A;  3TQ4 A;  1F7Q A;  2OKE A;  1F7R A;  1RN8 A;  1SIX A;  2OL1 A;  3MDX A;  4B0H A;  3ARN A;  2XY3 A;  2D4M A;  4OOQ A;  3TQ5 A;  1DUP A;  1DUC A;  3ECY A;  2D4N A;  3I93 A;  4GK6 A;  3ZEZ A;  3LOJ A;  3C3I A;  2HRM A;  2HQU A;  2HR6 A;  3TS6 A;  1F7O A;  3EHW A;  4AOO A;  1SNF A;  3TRN A;  3ZF5 A;  3MBQ A;  4AO5 A;  4XJC A;  3H6D A;  4WRK A;  4APZ 1;  3KM3 A;  1SM8 A;  1MQ7 A;  3H6X A;  1SJN A;  1PKK A;  3TQZ A;  3T70 A;  1XS1 A;  5CCT A;  5EDD A;  2QLP A;  4LHR A;  2ZDC A;  3HZA A;  5ECT A;  3TTA A;  3ZF6 A;  4DHK A;  3T60 A;  2HXB A;  2J4H A;  3TSL A;  3TRL A;  3CA9 A;  1PKH A;  2D4L A;  3C2T A;  3SO2 A;  2WE2 A;  4GCY A;  3ZF3 A;  5CCO A;  3TQ3 A;  3TPW A;  3GF0 A;  2Y8C A;  2BAZ A;  3T64 A;  3ZF4 A;  3ZF0 A;  1SYL A;  3HHQ A;  1Q5U X;  4OOP A;  3P48 A;  1F7D A;  2OL0 A;  1F7N A;  2WE3 A;  2Y1T A;  2QXX A;  1SEH A;  2PC5 A;  1XS4 A;  2R9Q A;  1EUW A;  1F7K A;  3TPN A;  1VYQ A;  5F9K A;  2J4Q A;  1SLH A;  1XS6 A;  2YZJ A;  1TUL A;  2V9X A;  2XCD A;  3TPY A;  2XX6 A;  2XCE A;  3ZF1 A;  3TP1 A;  1Q5H A;  2BT1 A;  3TPS A;  3T6Y A;  1SMC A;  3F4F A;  2WE1 A;  1DUT A;  2OKD A;  4AOZ A;  2WE0 A;  1DUD A;  2PY4 A;  3ARA A;  1F7P A;  1DUN A;  3ZF2 A;  2HXD A;  3LQW A;  4A6A A;  1OGH A;  1EU5 A;  2OKB A;  4GV8 A;  1RNJ A; 
#chains in the Genus database with same CATH homology
 2BSY A;  1PKJ A;  3TQ4 A;  1F7Q A;  2OKE A;  1F7R A;  1RN8 A;  1SIX A;  2OL1 A;  3MDX A;  4B0H A;  3ARN A;  2XY3 A;  2D4M A;  4OOQ A;  3TQ5 A;  1DUP A;  1DUC A;  3ECY A;  2D4N A;  3I93 A;  4GK6 A;  3ZEZ A;  3LOJ A;  3C3I A;  2HRM A;  2HQU A;  2HR6 A;  3TS6 A;  1F7O A;  3EHW A;  4AOO A;  1SNF A;  3TRN A;  3ZF5 A;  3MBQ A;  4AO5 A;  4XJC A;  3H6D A;  4WRK A;  4APZ 1;  3KM3 A;  1SM8 A;  1MQ7 A;  3H6X A;  1SJN A;  1PKK A;  3TQZ A;  3T70 A;  1XS1 A;  5CCT A;  5EDD A;  2QLP A;  4LHR A;  2ZDC A;  3HZA A;  5ECT A;  3TTA A;  3ZF6 A;  4DHK A;  3T60 A;  2HXB A;  2J4H A;  3TSL A;  3TRL A;  3CA9 A;  1PKH A;  2D4L A;  3C2T A;  3SO2 A;  2WE2 A;  4GCY A;  3ZF3 A;  5CCO A;  3TQ3 A;  3TPW A;  3GF0 A;  2Y8C A;  2BAZ A;  3T64 A;  3ZF4 A;  3ZF0 A;  1SYL A;  3HHQ A;  1Q5U X;  4OOP A;  3P48 A;  1F7D A;  2OL0 A;  1F7N A;  2WE3 A;  2Y1T A;  2QXX A;  1SEH A;  2PC5 A;  1XS4 A;  2R9Q A;  1EUW A;  1F7K A;  3TPN A;  1VYQ A;  5F9K A;  2J4Q A;  1SLH A;  1XS6 A;  2YZJ A;  2V9X A;  2XCD A;  3TPY A;  2XX6 A;  2XCE A;  3ZF1 A;  3TP1 A;  1Q5H A;  2BT1 A;  3TPS A;  3T6Y A;  1SMC A;  3F4F A;  2WE1 A;  1DUT A;  2OKD A;  4AOZ A;  2WE0 A;  1DUD A;  2PY4 A;  3ARA A;  1F7P A;  1DUN A;  3ZF2 A;  2HXD A;  3LQW A;  4A6A A;  1OGH A;  1EU5 A;  2OKB A;  4GV8 A;  1RNJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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