2WE3A

Ebv dutpase inactive mutant deleted of motif v
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
256
structure length
240
Chain Sequence
MEACPHIRYAFQNDKLLLQQGRLTLVNKTTILLRPMKTTTVDLGLYARPPEGHGLMLWGSTSRPVTSHVGIIDPGYTGELRLILQNQRRYNSTLRPSELKIHLAAFRYATPQPGDVGLDVSLPKDLALFPHQTVSVTLTVPPPSIPHHRPTIFGRSGLAMQGILVKPCRWRRGGVDVSLTNFSDQTVFLNKYRRFCQLVYLHKHHLTSFYSPHSDAGVLGPRSLFRWASCTFEEVPSLAM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Flexible Motif V of Epstein-Barr Virus Deoxyuridine 5'-Triphosphate Pyrophosphatase is Essential for Catalysis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Human herpesvirus 4
molecule keywords DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE
total genus 42
structure length 240
sequence length 256
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2009-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 2we3A01
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 2we3A02
2Y1TA 3MDXA 1EU5A 3ZEZA 2XCDA 4XJCA 3GF0A 5F9KA 3TPYA 4GK6A 4APZ1 1F7RA 2D4NA 3ZF4A 3TQ3A 2HXBA 3T70A 2HXDA 3TRLA 3HZAA 5ECTA 3TQ4A 4AOZA 2J4HA 3C2TA 3TS6A 1F7QA 1SJNA 2WE0A 2PY4A 3TTAA 1XS4A 3MBQA 1Q5UX 2YZJA 1Q5HA 2J4QA 2WE3A 2ZDCA 1SMCA 5CCOA 3TQ5A 1SEHA 5CCTA 2XX6A 3ZF5A 1PKJA 4LHRA 3KM3A 2V9XA 3H6DA 3ZF6A 4GV8A 3ECYA 3ZF1A 1EUWA 1MQ7A 4OOQA 2R9QA 4GCYA 1F7NA 3TQZA 4OOPA 3C3IA 3TPSA 1OGHA 3T64A 3ARAA 3T6YA 2PC5A 2Y8CA 1SNFA 3TPNA 2D4LA 1DUTA 4AO5A 1SLHA 2OL1A 2BSYA 2OKEA 3TPWA 4B0HA 4WRKA 3LOJA 3EHWA 1F7KA 3TP1A 1RNJA 1SM8A 4DHKA 2HR6A 1F7OA 1XS1A 2QLPA 1F7DA 2D4MA 3H6XA 3LQWA 1RN8A 4AOOA 3ZF0A 4A6AA 2HQUA 2BAZA 3ZF2A 3F4FA 3TSLA 1SIXA 2WE1A 3I93A 2OKBA 2XY3A 2HRMA 1SYLA 1PKKA 3HHQA 5EDDA 2XCEA 1F7PA 3CA9A 3ARNA 1DUPA 2WE2A 2OKDA 3SO2A 3TRNA 1XS6A 1DUCA 3ZF3A 2BT1A 3T60A 1PKHA 1DUDA 2QXXA 1DUNA 1VYQA 3P48A 2OL0A
chains in the Genus database with same CATH superfamily
2Y1TA 3MDXA 1EU5A 3ZEZA 2XCDA 4XJCA 3GF0A 5F9KA 3TPYA 4GK6A 4APZ1 1F7RA 2D4NA 3ZF4A 3TQ3A 2HXBA 3T70A 2HXDA 3TRLA 3HZAA 5ECTA 3TQ4A 4AOZA 2J4HA 3C2TA 3TS6A 1F7QA 1SJNA 2WE0A 2PY4A 3TTAA 1XS4A 3MBQA 1Q5UX 2YZJA 1Q5HA 2J4QA 2WE3A 2ZDCA 1SMCA 5CCOA 3TQ5A 1SEHA 5CCTA 2XX6A 3ZF5A 1PKJA 4LHRA 3KM3A 2V9XA 3H6DA 3ZF6A 4GV8A 3ECYA 3ZF1A 1EUWA 1MQ7A 4OOQA 2R9QA 4GCYA 1F7NA 3TQZA 4OOPA 3C3IA 3TPSA 1OGHA 3T64A 3ARAA 3T6YA 1TULA 2PC5A 2Y8CA 1SNFA 3TPNA 2D4LA 1DUTA 4AO5A 1SLHA 2OL1A 2BSYA 2OKEA 3TPWA 4B0HA 4WRKA 3LOJA 3EHWA 1F7KA 3TP1A 1RNJA 1SM8A 4DHKA 2HR6A 1F7OA 1XS1A 2QLPA 1F7DA 2D4MA 3H6XA 3LQWA 1RN8A 4AOOA 3ZF0A 4A6AA 2HQUA 2BAZA 3ZF2A 3F4FA 3TSLA 1SIXA 2WE1A 3I93A 2OKBA 2XY3A 2HRMA 1SYLA 1PKKA 3HHQA 5EDDA 2XCEA 1F7PA 3CA9A 3ARNA 1DUPA 2WE2A 2OKDA 3SO2A 3TRNA 1XS6A 1DUCA 3ZF3A 2BT1A 3T60A 1PKHA 1DUDA 2QXXA 1DUNA 1VYQA 3P48A 2OL0A
chains in the Genus database with same CATH topology
2Y1TA 3MDXA 1EU5A 3ZEZA 2XCDA 4XJCA 3GF0A 5F9KA 3TPYA 4GK6A 4APZ1 1F7RA 2D4NA 3ZF4A 3TQ3A 2HXBA 3T70A 2HXDA 3TRLA 3HZAA 5ECTA 3TQ4A 4AOZA 2J4HA 3C2TA 3TS6A 1F7QA 1SJNA 2WE0A 2PY4A 3TTAA 1XS4A 3MBQA 1Q5UX 2YZJA 1Q5HA 2J4QA 2WE3A 2ZDCA 1SMCA 5CCOA 3TQ5A 1SEHA 5CCTA 2XX6A 3ZF5A 1PKJA 4LHRA 3KM3A 2V9XA 3H6DA 3ZF6A 4GV8A 3ECYA 3ZF1A 1EUWA 1MQ7A 4OOQA 2R9QA 4GCYA 1F7NA 3TQZA 4OOPA 3C3IA 3TPSA 1OGHA 3T64A 3ARAA 3T6YA 2PC5A 2Y8CA 1SNFA 3TPNA 2D4LA 1DUTA 4AO5A 1SLHA 2OL1A 2BSYA 2OKEA 3TPWA 4B0HA 4WRKA 3LOJA 3EHWA 1F7KA 3TP1A 1RNJA 1SM8A 4DHKA 2HR6A 1F7OA 1XS1A 2QLPA 1F7DA 2D4MA 3H6XA 3LQWA 1RN8A 4AOOA 3ZF0A 4A6AA 2HQUA 2BAZA 3ZF2A 3F4FA 3TSLA 1SIXA 2WE1A 3I93A 2OKBA 2XY3A 2HRMA 1SYLA 1PKKA 3HHQA 5EDDA 2XCEA 1F7PA 3CA9A 3ARNA 1DUPA 2WE2A 2OKDA 3SO2A 3TRNA 1XS6A 1DUCA 3ZF3A 2BT1A 3T60A 1PKHA 1DUDA 2QXXA 1DUNA 1VYQA 3P48A 2OL0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y1T A;  3MDX A;  1EU5 A;  3ZEZ A;  2XCD A;  4XJC A;  3GF0 A;  5F9K A;  3TPY A;  4GK6 A;  4APZ 1;  1F7R A;  2D4N A;  3ZF4 A;  3TQ3 A;  2HXB A;  3T70 A;  2HXD A;  3TRL A;  3HZA A;  5ECT A;  3TQ4 A;  4AOZ A;  2J4H A;  3C2T A;  3TS6 A;  1F7Q A;  1SJN A;  2WE0 A;  2PY4 A;  3TTA A;  1XS4 A;  3MBQ A;  1Q5U X;  2YZJ A;  1Q5H A;  2J4Q A;  2WE3 A;  2ZDC A;  1SMC A;  5CCO A;  3TQ5 A;  1SEH A;  5CCT A;  2XX6 A;  3ZF5 A;  1PKJ A;  4LHR A;  3KM3 A;  2V9X A;  3H6D A;  3ZF6 A;  4GV8 A;  3ECY A;  3ZF1 A;  1EUW A;  1MQ7 A;  4OOQ A;  2R9Q A;  4GCY A;  1F7N A;  3TQZ A;  4OOP A;  3C3I A;  3TPS A;  1OGH A;  3T64 A;  3ARA A;  3T6Y A;  2PC5 A;  2Y8C A;  1SNF A;  3TPN A;  2D4L A;  1DUT A;  4AO5 A;  1SLH A;  2OL1 A;  2BSY A;  2OKE A;  3TPW A;  4B0H A;  4WRK A;  3LOJ A;  3EHW A;  1F7K A;  3TP1 A;  1RNJ A;  1SM8 A;  4DHK A;  2HR6 A;  1F7O A;  1XS1 A;  2QLP A;  1F7D A;  2D4M A;  3H6X A;  3LQW A;  1RN8 A;  4AOO A;  3ZF0 A;  4A6A A;  2HQU A;  2BAZ A;  3ZF2 A;  3F4F A;  3TSL A;  1SIX A;  2WE1 A;  3I93 A;  2OKB A;  2XY3 A;  2HRM A;  1SYL A;  1PKK A;  3HHQ A;  5EDD A;  2XCE A;  1F7P A;  3CA9 A;  3ARN A;  1DUP A;  2WE2 A;  2OKD A;  3SO2 A;  3TRN A;  1XS6 A;  1DUC A;  3ZF3 A;  2BT1 A;  3T60 A;  1PKH A;  1DUD A;  2QXX A;  1DUN A;  1VYQ A;  3P48 A;  2OL0 A; 
#chains in the Genus database with same CATH topology
 2Y1T A;  3MDX A;  1EU5 A;  3ZEZ A;  2XCD A;  4XJC A;  3GF0 A;  5F9K A;  3TPY A;  4GK6 A;  4APZ 1;  1F7R A;  2D4N A;  3ZF4 A;  3TQ3 A;  2HXB A;  3T70 A;  2HXD A;  3TRL A;  3HZA A;  5ECT A;  3TQ4 A;  4AOZ A;  2J4H A;  3C2T A;  3TS6 A;  1F7Q A;  1SJN A;  2WE0 A;  2PY4 A;  3TTA A;  1XS4 A;  3MBQ A;  1Q5U X;  2YZJ A;  1Q5H A;  2J4Q A;  2WE3 A;  2ZDC A;  1SMC A;  5CCO A;  3TQ5 A;  1SEH A;  5CCT A;  2XX6 A;  3ZF5 A;  1PKJ A;  4LHR A;  3KM3 A;  2V9X A;  3H6D A;  3ZF6 A;  4GV8 A;  3ECY A;  3ZF1 A;  1EUW A;  1MQ7 A;  4OOQ A;  2R9Q A;  4GCY A;  1F7N A;  3TQZ A;  4OOP A;  3C3I A;  3TPS A;  1OGH A;  3T64 A;  3ARA A;  3T6Y A;  1TUL A;  2PC5 A;  2Y8C A;  1SNF A;  3TPN A;  2D4L A;  1DUT A;  4AO5 A;  1SLH A;  2OL1 A;  2BSY A;  2OKE A;  3TPW A;  4B0H A;  4WRK A;  3LOJ A;  3EHW A;  1F7K A;  3TP1 A;  1RNJ A;  1SM8 A;  4DHK A;  2HR6 A;  1F7O A;  1XS1 A;  2QLP A;  1F7D A;  2D4M A;  3H6X A;  3LQW A;  1RN8 A;  4AOO A;  3ZF0 A;  4A6A A;  2HQU A;  2BAZ A;  3ZF2 A;  3F4F A;  3TSL A;  1SIX A;  2WE1 A;  3I93 A;  2OKB A;  2XY3 A;  2HRM A;  1SYL A;  1PKK A;  3HHQ A;  5EDD A;  2XCE A;  1F7P A;  3CA9 A;  3ARN A;  1DUP A;  2WE2 A;  2OKD A;  3SO2 A;  3TRN A;  1XS6 A;  1DUC A;  3ZF3 A;  2BT1 A;  3T60 A;  1PKH A;  1DUD A;  2QXX A;  1DUN A;  1VYQ A;  3P48 A;  2OL0 A; 
#chains in the Genus database with same CATH homology
 2Y1T A;  3MDX A;  1EU5 A;  3ZEZ A;  2XCD A;  4XJC A;  3GF0 A;  5F9K A;  3TPY A;  4GK6 A;  4APZ 1;  1F7R A;  2D4N A;  3ZF4 A;  3TQ3 A;  2HXB A;  3T70 A;  2HXD A;  3TRL A;  3HZA A;  5ECT A;  3TQ4 A;  4AOZ A;  2J4H A;  3C2T A;  3TS6 A;  1F7Q A;  1SJN A;  2WE0 A;  2PY4 A;  3TTA A;  1XS4 A;  3MBQ A;  1Q5U X;  2YZJ A;  1Q5H A;  2J4Q A;  2WE3 A;  2ZDC A;  1SMC A;  5CCO A;  3TQ5 A;  1SEH A;  5CCT A;  2XX6 A;  3ZF5 A;  1PKJ A;  4LHR A;  3KM3 A;  2V9X A;  3H6D A;  3ZF6 A;  4GV8 A;  3ECY A;  3ZF1 A;  1EUW A;  1MQ7 A;  4OOQ A;  2R9Q A;  4GCY A;  1F7N A;  3TQZ A;  4OOP A;  3C3I A;  3TPS A;  1OGH A;  3T64 A;  3ARA A;  3T6Y A;  2PC5 A;  2Y8C A;  1SNF A;  3TPN A;  2D4L A;  1DUT A;  4AO5 A;  1SLH A;  2OL1 A;  2BSY A;  2OKE A;  3TPW A;  4B0H A;  4WRK A;  3LOJ A;  3EHW A;  1F7K A;  3TP1 A;  1RNJ A;  1SM8 A;  4DHK A;  2HR6 A;  1F7O A;  1XS1 A;  2QLP A;  1F7D A;  2D4M A;  3H6X A;  3LQW A;  1RN8 A;  4AOO A;  3ZF0 A;  4A6A A;  2HQU A;  2BAZ A;  3ZF2 A;  3F4F A;  3TSL A;  1SIX A;  2WE1 A;  3I93 A;  2OKB A;  2XY3 A;  2HRM A;  1SYL A;  1PKK A;  3HHQ A;  5EDD A;  2XCE A;  1F7P A;  3CA9 A;  3ARN A;  1DUP A;  2WE2 A;  2OKD A;  3SO2 A;  3TRN A;  1XS6 A;  1DUC A;  3ZF3 A;  2BT1 A;  3T60 A;  1PKH A;  1DUD A;  2QXX A;  1DUN A;  1VYQ A;  3P48 A;  2OL0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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