2WQIA

Crystal structure of the human p73 tetramerization domain
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
45
structure length
45
Chain Sequence
EDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords TUMOR PROTEIN P73
total genus 14
structure length 45
sequence length 45
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2009-08-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.170.10 Few Secondary Structures Irregular p53, subunit A p53-like tetramerisation domain 2wqiA00
1SALA 1SAEA 5HOCA 4A9ZA 2WTTA 1OLGA 1SAFA 2MW4A 2WQIA 5HOBA 2KBYA 3ZY1A 1SAKA 3SAKA 1OLHA
chains in the Genus database with same CATH superfamily
1SALA 1SAEA 5HOCA 4A9ZA 2WTTA 1OLGA 1SAFA 2MW4A 2WQIA 5HOBA 2KBYA 3ZY1A 1SAKA 3SAKA 1OLHA
chains in the Genus database with same CATH topology
1SALA 1SAEA 5HOCA 4A9ZA 2WTTA 1OLGA 1SAFA 2MW4A 2WQIA 5HOBA 2KBYA 3ZY1A 1SAKA 3SAKA 1OLHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SAL A;  1SAE A;  5HOC A;  4A9Z A;  2WTT A;  1OLG A;  1SAF A;  2MW4 A;  2WQI A;  5HOB A;  2KBY A;  3ZY1 A;  1SAK A;  3SAK A;  1OLH A; 
#chains in the Genus database with same CATH topology
 1SAL A;  1SAE A;  5HOC A;  4A9Z A;  2WTT A;  1OLG A;  1SAF A;  2MW4 A;  2WQI A;  5HOB A;  2KBY A;  3ZY1 A;  1SAK A;  3SAK A;  1OLH A; 
#chains in the Genus database with same CATH homology
 1SAL A;  1SAE A;  5HOC A;  4A9Z A;  2WTT A;  1OLG A;  1SAF A;  2MW4 A;  2WQI A;  5HOB A;  2KBY A;  3ZY1 A;  1SAK A;  3SAK A;  1OLH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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