2WTTA

Structure of the human p73 tetramerization domain (crystal form ii)
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
42
structure length
42
Chain Sequence
EDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords TUMOR PROTEIN P73
total genus 10
structure length 42
sequence length 42
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
ec nomenclature
pdb deposition date 2009-09-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.170.10 Few Secondary Structures Irregular p53, subunit A p53-like tetramerisation domain 2wttA00
2WTTA 1SAFA 2KBYA 1SALA 5HOBA 5HOCA 3ZY1A 2WQIA 3SAKA 4A9ZA 1OLGA 2MW4A 1SAKA 1OLHA 1SAEA
chains in the Genus database with same CATH superfamily
2WTTA 1SAFA 2KBYA 1SALA 5HOBA 5HOCA 3ZY1A 2WQIA 3SAKA 4A9ZA 1OLGA 2MW4A 1SAKA 1OLHA 1SAEA
chains in the Genus database with same CATH topology
2WTTA 1SAFA 2KBYA 1SALA 5HOBA 5HOCA 3ZY1A 2WQIA 3SAKA 4A9ZA 1OLGA 2MW4A 1SAKA 1OLHA 1SAEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WTT A;  1SAF A;  2KBY A;  1SAL A;  5HOB A;  5HOC A;  3ZY1 A;  2WQI A;  3SAK A;  4A9Z A;  1OLG A;  2MW4 A;  1SAK A;  1OLH A;  1SAE A; 
#chains in the Genus database with same CATH topology
 2WTT A;  1SAF A;  2KBY A;  1SAL A;  5HOB A;  5HOC A;  3ZY1 A;  2WQI A;  3SAK A;  4A9Z A;  1OLG A;  2MW4 A;  1SAK A;  1OLH A;  1SAE A; 
#chains in the Genus database with same CATH homology
 2WTT A;  1SAF A;  2KBY A;  1SAL A;  5HOB A;  5HOC A;  3ZY1 A;  2WQI A;  3SAK A;  4A9Z A;  1OLG A;  2MW4 A;  1SAK A;  1OLH A;  1SAE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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