3A8MA

Crystal structure of nitrile hydratase mutant y72f complexed with trimethylacetonitrile
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
197
structure length
195
Chain Sequence
ENAAPAQAPVSDRAWALFRALDGKGLVPDGYVEGWKKTFEEDFSPRRGAELVARAWTDPEFRQLLLTDGTAAVAQYGYLGPQGEYIVAVEDTPTLKNVIVCSLSTAWPILGLPPTWYKSFEYRARVVREPRKVLSEMGTEIASDIEIRVYDTTAETRYMVLPQRPAGTEGWSQEQLQEIVTKDCLIGVAIPQVPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Kinetic and structural studies on roles of the serine ligand and a strictly conserved tyrosine residue in nitrile hydratase
pubmed doi rcsb
molecule tags Lyase
source organism Rhodococcus erythropolis
molecule keywords Nitrile hydratase subunit alpha
total genus 59
structure length 195
sequence length 197
ec nomenclature ec 4.2.1.84: Nitrile hydratase.
pdb deposition date 2009-10-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02979 NHase_alpha Nitrile hydratase, alpha chain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.330.10 Alpha Beta Alpha-Beta Complex Nitrile Hydratase; Chain A Nitrile hydratase alpha /Thiocyanate hydrolase gamma 3a8mA00
2ZPBA 2DXCC 3HHTA 1UGQA 3A8OA 2QDYA 3WVEA 2ZPHA 3A8HA 4FM4A 4OB3A 2CYZA 3QXEA 3VYGC 3X25A 3X26A 2ZPFA 1IREA 1UGSA 2CZ1A 4ZGEA 4OB0A 3QZ9A 4OB2A 2ZZDC 2DD5C 2DPPA 1UGRA 3A8MA 1UGPA 2ZPGA 3VYHA 1AHJA 2ZPEA 3A8LA 3A8GA 3QYHA 2ZCFA 2AHJA 3QZ5A 2CZ7A 4OB1A 3X24A 4ZGDA 2D0QA 2DXBC 3X20A 2ZPIA 3QYGA 3X28A 3WVDA 1V29A 2DD4C 4ZGJA 2CZ0A 2CZ6A
chains in the Genus database with same CATH superfamily
2ZPBA 2DXCC 3HHTA 1UGQA 3A8OA 2QDYA 3WVEA 2ZPHA 3A8HA 4FM4A 4OB3A 2CYZA 3QXEA 3VYGC 3X25A 3X26A 2ZPFA 1IREA 1UGSA 2CZ1A 4ZGEA 4OB0A 3QZ9A 4OB2A 2ZZDC 2DD5C 2DPPA 1UGRA 3A8MA 1UGPA 2ZPGA 3VYHA 1AHJA 2ZPEA 3A8LA 3A8GA 3QYHA 2ZCFA 2AHJA 3QZ5A 2CZ7A 4OB1A 3X24A 4ZGDA 2D0QA 2DXBC 3X20A 2ZPIA 3QYGA 3X28A 3WVDA 1V29A 2DD4C 4ZGJA 2CZ0A 2CZ6A
chains in the Genus database with same CATH topology
2ZPBA 2DXCC 3HHTA 1UGQA 3A8OA 2QDYA 3WVEA 2ZPHA 3A8HA 4FM4A 4OB3A 2CYZA 3QXEA 3VYGC 3X25A 3X26A 2ZPFA 1IREA 1UGSA 2CZ1A 4ZGEA 4OB0A 3QZ9A 4OB2A 2ZZDC 2DD5C 2DPPA 1UGRA 3A8MA 1UGPA 2ZPGA 3VYHA 1AHJA 2ZPEA 3A8LA 3A8GA 3QYHA 2ZCFA 2AHJA 3QZ5A 2CZ7A 4OB1A 3X24A 4ZGDA 2D0QA 2DXBC 3X20A 2ZPIA 3QYGA 3X28A 3WVDA 1V29A 2DD4C 4ZGJA 2CZ0A 2CZ6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZPB A;  2DXC C;  3HHT A;  1UGQ A;  3A8O A;  2QDY A;  3WVE A;  2ZPH A;  3A8H A;  4FM4 A;  4OB3 A;  2CYZ A;  3QXE A;  3VYG C;  3X25 A;  3X26 A;  2ZPF A;  1IRE A;  1UGS A;  2CZ1 A;  4ZGE A;  4OB0 A;  3QZ9 A;  4OB2 A;  2ZZD C;  2DD5 C;  2DPP A;  1UGR A;  3A8M A;  1UGP A;  2ZPG A;  3VYH A;  1AHJ A;  2ZPE A;  3A8L A;  3A8G A;  3QYH A;  2ZCF A;  2AHJ A;  3QZ5 A;  2CZ7 A;  4OB1 A;  3X24 A;  4ZGD A;  2D0Q A;  2DXB C;  3X20 A;  2ZPI A;  3QYG A;  3X28 A;  3WVD A;  1V29 A;  2DD4 C;  4ZGJ A;  2CZ0 A;  2CZ6 A; 
#chains in the Genus database with same CATH topology
 2ZPB A;  2DXC C;  3HHT A;  1UGQ A;  3A8O A;  2QDY A;  3WVE A;  2ZPH A;  3A8H A;  4FM4 A;  4OB3 A;  2CYZ A;  3QXE A;  3VYG C;  3X25 A;  3X26 A;  2ZPF A;  1IRE A;  1UGS A;  2CZ1 A;  4ZGE A;  4OB0 A;  3QZ9 A;  4OB2 A;  2ZZD C;  2DD5 C;  2DPP A;  1UGR A;  3A8M A;  1UGP A;  2ZPG A;  3VYH A;  1AHJ A;  2ZPE A;  3A8L A;  3A8G A;  3QYH A;  2ZCF A;  2AHJ A;  3QZ5 A;  2CZ7 A;  4OB1 A;  3X24 A;  4ZGD A;  2D0Q A;  2DXB C;  3X20 A;  2ZPI A;  3QYG A;  3X28 A;  3WVD A;  1V29 A;  2DD4 C;  4ZGJ A;  2CZ0 A;  2CZ6 A; 
#chains in the Genus database with same CATH homology
 2ZPB A;  2DXC C;  3HHT A;  1UGQ A;  3A8O A;  2QDY A;  3WVE A;  2ZPH A;  3A8H A;  4FM4 A;  4OB3 A;  2CYZ A;  3QXE A;  3VYG C;  3X25 A;  3X26 A;  2ZPF A;  1IRE A;  1UGS A;  2CZ1 A;  4ZGE A;  4OB0 A;  3QZ9 A;  4OB2 A;  2ZZD C;  2DD5 C;  2DPP A;  1UGR A;  3A8M A;  1UGP A;  2ZPG A;  3VYH A;  1AHJ A;  2ZPE A;  3A8L A;  3A8G A;  3QYH A;  2ZCF A;  2AHJ A;  3QZ5 A;  2CZ7 A;  4OB1 A;  3X24 A;  4ZGD A;  2D0Q A;  2DXB C;  3X20 A;  2ZPI A;  3QYG A;  3X28 A;  3WVD A;  1V29 A;  2DD4 C;  4ZGJ A;  2CZ0 A;  2CZ6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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