3CCLC

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 63
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 3cclC00
1QVFC 1W2BC 1Q7YE 1M1KE 1YITC 1YJNC 1VQPC 1VQOC 1VQ8C 1VQ7C 3CC4C 1VQKC 1KC8E 3CMAC 1N8RE 3G71C 1DMGA 3CCSC 3CXCC 3CCJC 1K9ME 1NJIE 1QVGC 1VQ6C 1VQMC 1YJWC 5DM7C 3J7YF 3I56C 3CPWC 3CCEC 1K8AE 2OTLC 1JJ2C 1VQNC 3G4SC 1Q86E 2QEXC 1K73E 1VQ5C 3CCQC 3CMEC 3CCRC 1S72C 1KD1E 3CC7C 1VQ9C 1YHQC 2QA4C 1KQSC 1YJ9C 1VQ4C 2OTJC 3OW2C 1M90E 1VQLC 4V19F 3CCLC 3CCMC 1Q81E 1Q82E 3CCVC 3CD6C 3I55C 1YI2C 3G6EC 3CCUC 3CC2C 1YIJC
chains in the Genus database with same CATH superfamily
1QVFC 1W2BC 1Q7YE 1M1KE 1YITC 1YJNC 1VQPC 1VQOC 1VQ8C 1VQ7C 3CC4C 1VQKC 1KC8E 3CMAC 1N8RE 3G71C 1DMGA 3CCSC 3CXCC 3CCJC 1K9ME 1NJIE 1QVGC 1VQ6C 1VQMC 1YJWC 5DM7C 3J7YF 3I56C 3CPWC 3CCEC 1K8AE 2OTLC 1JJ2C 1VQNC 3G4SC 1Q86E 2QEXC 1K73E 1VQ5C 3CCQC 3CMEC 3CCRC 1S72C 1KD1E 3CC7C 1VQ9C 1YHQC 2QA4C 1KQSC 1YJ9C 1VQ4C 2OTJC 3OW2C 1M90E 1VQLC 4V19F 3CCLC 3CCMC 1Q81E 1Q82E 3CCVC 3CD6C 3I55C 1YI2C 3G6EC 3CCUC 3CC2C 1YIJC
chains in the Genus database with same CATH topology
1QVFC 1W2BC 1Q7YE 1M1KE 1YITC 1YJNC 1VQPC 1VQOC 1VQ8C 1VQ7C 3CC4C 1VQKC 1KC8E 3CMAC 1N8RE 3G71C 1DMGA 3CCSC 3CXCC 3CCJC 1K9ME 1NJIE 1QVGC 1VQ6C 1VQMC 1YJWC 5DM7C 3J7YF 3I56C 3CPWC 3CCEC 1K8AE 2OTLC 1JJ2C 1VQNC 3G4SC 1Q86E 2QEXC 1K73E 1VQ5C 3CCQC 3CMEC 3CCRC 1S72C 1KD1E 3CC7C 1VQ9C 1YHQC 2QA4C 1KQSC 1YJ9C 1VQ4C 2OTJC 3OW2C 1M90E 1VQLC 4V19F 3CCLC 3CCMC 1Q81E 1Q82E 3CCVC 3CD6C 3I55C 1YI2C 3G6EC 3CCUC 3CC2C 1YIJC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QVF C;  1W2B C;  1Q7Y E;  1M1K E;  1YIT C;  1YJN C;  1VQP C;  1VQO C;  1VQ8 C;  1VQ7 C;  3CC4 C;  1VQK C;  1KC8 E;  3CMA C;  1N8R E;  3G71 C;  1DMG A;  3CCS C;  3CXC C;  3CCJ C;  1K9M E;  1NJI E;  1QVG C;  1VQ6 C;  1VQM C;  1YJW C;  5DM7 C;  3J7Y F;  3I56 C;  3CPW C;  3CCE C;  1K8A E;  2OTL C;  1JJ2 C;  1VQN C;  3G4S C;  1Q86 E;  2QEX C;  1K73 E;  1VQ5 C;  3CCQ C;  3CME C;  3CCR C;  1S72 C;  1KD1 E;  3CC7 C;  1VQ9 C;  1YHQ C;  2QA4 C;  1KQS C;  1YJ9 C;  1VQ4 C;  2OTJ C;  3OW2 C;  1M90 E;  1VQL C;  4V19 F;  3CCL C;  3CCM C;  1Q81 E;  1Q82 E;  3CCV C;  3CD6 C;  3I55 C;  1YI2 C;  3G6E C;  3CCU C;  3CC2 C;  1YIJ C; 
#chains in the Genus database with same CATH topology
 1QVF C;  1W2B C;  1Q7Y E;  1M1K E;  1YIT C;  1YJN C;  1VQP C;  1VQO C;  1VQ8 C;  1VQ7 C;  3CC4 C;  1VQK C;  1KC8 E;  3CMA C;  1N8R E;  3G71 C;  1DMG A;  3CCS C;  3CXC C;  3CCJ C;  1K9M E;  1NJI E;  1QVG C;  1VQ6 C;  1VQM C;  1YJW C;  5DM7 C;  3J7Y F;  3I56 C;  3CPW C;  3CCE C;  1K8A E;  2OTL C;  1JJ2 C;  1VQN C;  3G4S C;  1Q86 E;  2QEX C;  1K73 E;  1VQ5 C;  3CCQ C;  3CME C;  3CCR C;  1S72 C;  1KD1 E;  3CC7 C;  1VQ9 C;  1YHQ C;  2QA4 C;  1KQS C;  1YJ9 C;  1VQ4 C;  2OTJ C;  3OW2 C;  1M90 E;  1VQL C;  4V19 F;  3CCL C;  3CCM C;  1Q81 E;  1Q82 E;  3CCV C;  3CD6 C;  3I55 C;  1YI2 C;  3G6E C;  3CCU C;  3CC2 C;  1YIJ C; 
#chains in the Genus database with same CATH homology
 1QVF C;  1W2B C;  1Q7Y E;  1M1K E;  1YIT C;  1YJN C;  1VQP C;  1VQO C;  1VQ8 C;  1VQ7 C;  3CC4 C;  1VQK C;  1KC8 E;  3CMA C;  1N8R E;  3G71 C;  1DMG A;  3CCS C;  3CXC C;  3CCJ C;  1K9M E;  1NJI E;  1QVG C;  1VQ6 C;  1VQM C;  1YJW C;  5DM7 C;  3J7Y F;  3I56 C;  3CPW C;  3CCE C;  1K8A E;  2OTL C;  1JJ2 C;  1VQN C;  3G4S C;  1Q86 E;  2QEX C;  1K73 E;  1VQ5 C;  3CCQ C;  3CME C;  3CCR C;  1S72 C;  1KD1 E;  3CC7 C;  1VQ9 C;  1YHQ C;  2QA4 C;  1KQS C;  1YJ9 C;  1VQ4 C;  2OTJ C;  3OW2 C;  1M90 E;  1VQL C;  4V19 F;  3CCL C;  3CCM C;  1Q81 E;  1Q82 E;  3CCV C;  3CD6 C;  3I55 C;  1YI2 C;  3G6E C;  3CCU C;  3CC2 C;  1YIJ C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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