3CCM2

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2611u
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
49
structure length
46
Chain Sequence
GKKSKATKKRLAKLDNQNSRVPAWVMLKTDRRNHKRRHWRRNDTDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 10
structure length 46
sequence length 49
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
2 PF00832 Ribosomal_L39 Ribosomal L39 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1620.10 Mainly Alpha Orthogonal Bundle Atp Synthase Epsilon Chain; Chain: I; Ribosomal protein L39e 3ccm200
1VQO2 1VQM2 1Q813 1KD13 3CD62 2QA42 1Q863 1YJN2 1K8A3 3CCV2 1M1K3 3CCE2 3CC42 3CME2 1JJ21 1K9M3 1K733 3CCS2 1YHQ2 1KC83 1N8R3 3CPW1 1NJI3 1VQ72 1Q823 1Q7Y3 1VQ82 1VQK2 3CCM2 3CCJ2 1QVF1 3CC22 3G712 1VQ62 3CCR2 1KQS1 3I562 2OTL2 3CCU2 1YI22 3OW21 1M903 1YJW2 1QVG1 3G6E2 1S722 1VQP2 1YIJ2 1VQN2 2OTJ2 3CC72 3CXC1 3CMA2 1VQ92 3I552 3G4S2 3CCQ2 3CCL2 1YIT2 1W2B1 1VQL2 1VQ52 1YJ92 2QEX2 1VQ42
chains in the Genus database with same CATH superfamily
3OFNI 1VQO2 1VQM2 1Q813 1KD13 3CD62 2WSSI 2WPDI 2QA42 1Q863 1YJN2 1K8A3 3CCV2 1M1K3 3CCE2 3CC42 3CME2 1JJ21 1K9M3 1K733 3CCS2 1YHQ2 1KC83 4YXWI 2XOKI 1N8R3 3CPW1 1NJI3 1VQ72 1Q823 1Q7Y3 1VQ82 1VQK2 3CCM2 3CCJ2 1QVF1 3CC22 2V7QI 3G712 3CCR2 1VQ62 1KQS1 3I562 2OTL2 3CCU2 1YI22 3OW21 1M903 1YJW2 3ZIAI 1QVG1 3G6E2 2XNDI 1S722 1E79I 1VQP2 1YIJ2 1VQN2 2OTJ2 3CC72 3CXC1 3CMA2 1VQ92 3I552 3G4S2 3CCQ2 3CCL2 1YIT2 1W2B1 1VQL2 1VQ52 1YJ92 2QEX2 1VQ42
chains in the Genus database with same CATH topology
1VQO2 1VQM2 1Q813 1KD13 3CD62 2QA42 1Q863 1YJN2 1K8A3 3CCV2 1M1K3 3CCE2 3CC42 3CME2 1JJ21 1K9M3 1K733 3CCS2 1YHQ2 1KC83 1N8R3 3CPW1 1NJI3 1VQ72 1Q823 1Q7Y3 1VQ82 1VQK2 3CCM2 3CCJ2 1QVF1 3CC22 3G712 1VQ62 3CCR2 1KQS1 3I562 2OTL2 3CCU2 1YI22 3OW21 1M903 1YJW2 1QVG1 3G6E2 1S722 1VQP2 1YIJ2 1VQN2 2OTJ2 3CC72 3CXC1 3CMA2 1VQ92 3I552 3G4S2 3CCQ2 3CCL2 1YIT2 1W2B1 1VQL2 1VQ52 1YJ92 2QEX2 1VQ42
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQO 2;  1VQM 2;  1Q81 3;  1KD1 3;  3CD6 2;  2QA4 2;  1Q86 3;  1YJN 2;  1K8A 3;  3CCV 2;  1M1K 3;  3CCE 2;  3CC4 2;  3CME 2;  1JJ2 1;  1K9M 3;  1K73 3;  3CCS 2;  1YHQ 2;  1KC8 3;  1N8R 3;  3CPW 1;  1NJI 3;  1VQ7 2;  1Q82 3;  1Q7Y 3;  1VQ8 2;  1VQK 2;  3CCM 2;  3CCJ 2;  1QVF 1;  3CC2 2;  3G71 2;  1VQ6 2;  3CCR 2;  1KQS 1;  3I56 2;  2OTL 2;  3CCU 2;  1YI2 2;  3OW2 1;  1M90 3;  1YJW 2;  1QVG 1;  3G6E 2;  1S72 2;  1VQP 2;  1YIJ 2;  1VQN 2;  2OTJ 2;  3CC7 2;  3CXC 1;  3CMA 2;  1VQ9 2;  3I55 2;  3G4S 2;  3CCQ 2;  3CCL 2;  1YIT 2;  1W2B 1;  1VQL 2;  1VQ5 2;  1YJ9 2;  2QEX 2;  1VQ4 2; 
#chains in the Genus database with same CATH topology
 3OFN I;  1VQO 2;  1VQM 2;  1Q81 3;  1KD1 3;  3CD6 2;  2WSS I;  2WPD I;  2QA4 2;  1Q86 3;  1YJN 2;  1K8A 3;  3CCV 2;  1M1K 3;  3CCE 2;  3CC4 2;  3CME 2;  1JJ2 1;  1K9M 3;  1K73 3;  3CCS 2;  1YHQ 2;  1KC8 3;  4YXW I;  2XOK I;  1N8R 3;  3CPW 1;  1NJI 3;  1VQ7 2;  1Q82 3;  1Q7Y 3;  1VQ8 2;  1VQK 2;  3CCM 2;  3CCJ 2;  1QVF 1;  3CC2 2;  2V7Q I;  3G71 2;  3CCR 2;  1VQ6 2;  1KQS 1;  3I56 2;  2OTL 2;  3CCU 2;  1YI2 2;  3OW2 1;  1M90 3;  1YJW 2;  3ZIA I;  1QVG 1;  3G6E 2;  2XND I;  1S72 2;  1E79 I;  1VQP 2;  1YIJ 2;  1VQN 2;  2OTJ 2;  3CC7 2;  3CXC 1;  3CMA 2;  1VQ9 2;  3I55 2;  3G4S 2;  3CCQ 2;  3CCL 2;  1YIT 2;  1W2B 1;  1VQL 2;  1VQ5 2;  1YJ9 2;  2QEX 2;  1VQ4 2; 
#chains in the Genus database with same CATH homology
 1VQO 2;  1VQM 2;  1Q81 3;  1KD1 3;  3CD6 2;  2QA4 2;  1Q86 3;  1YJN 2;  1K8A 3;  3CCV 2;  1M1K 3;  3CCE 2;  3CC4 2;  3CME 2;  1JJ2 1;  1K9M 3;  1K73 3;  3CCS 2;  1YHQ 2;  1KC8 3;  1N8R 3;  3CPW 1;  1NJI 3;  1VQ7 2;  1Q82 3;  1Q7Y 3;  1VQ8 2;  1VQK 2;  3CCM 2;  3CCJ 2;  1QVF 1;  3CC2 2;  3G71 2;  1VQ6 2;  3CCR 2;  1KQS 1;  3I56 2;  2OTL 2;  3CCU 2;  1YI2 2;  3OW2 1;  1M90 3;  1YJW 2;  1QVG 1;  3G6E 2;  1S72 2;  1VQP 2;  1YIJ 2;  1VQN 2;  2OTJ 2;  3CC7 2;  3CXC 1;  3CMA 2;  1VQ9 2;  3I55 2;  3G4S 2;  3CCQ 2;  3CCL 2;  1YIT 2;  1W2B 1;  1VQL 2;  1VQ5 2;  1YJ9 2;  2QEX 2;  1VQ4 2; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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