3CCQ2

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488u
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
49
structure length
46
Chain Sequence
GKKSKATKKRLAKLDNQNSRVPAWVMLKTDRRNHKRRHWRRNDTDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 9
structure length 46
sequence length 49
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
2 PF00832 Ribosomal_L39 Ribosomal L39 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1620.10 Mainly Alpha Orthogonal Bundle Atp Synthase Epsilon Chain; Chain: I; Ribosomal protein L39e 3ccq200
1VQK2 3CCR2 1QVG1 1JJ21 3I562 1YJN2 2QEX2 3CC72 1VQM2 1YI22 1QVF1 1W2B1 3CD62 1VQO2 3CCU2 1K8A3 1VQN2 1VQP2 3CMA2 3CCM2 1VQ72 2QA42 3CCS2 3CCL2 1M1K3 1YIJ2 3CC22 1KD13 3G6E2 1NJI3 1VQ62 2OTL2 1VQ42 1Q813 3OW21 1YIT2 1KQS1 3CPW1 3CCJ2 1Q863 1VQL2 1M903 1VQ52 1YJW2 1Q7Y3 3CCV2 3CCQ2 3CC42 1YHQ2 3G712 1Q823 1K9M3 3I552 3CXC1 1N8R3 1S722 1VQ92 2OTJ2 3CCE2 1KC83 1YJ92 1K733 3G4S2 3CME2 1VQ82
chains in the Genus database with same CATH superfamily
1VQK2 3CCR2 1QVG1 1JJ21 3I562 1YJN2 2QEX2 3CC72 1VQM2 1YI22 1QVF1 1W2B1 3CD62 3ZIAI 1VQO2 3CCU2 3OFNI 1K8A3 1VQN2 1VQP2 2WPDI 3CMA2 3CCM2 1VQ72 2QA42 3CCS2 3CCL2 1M1K3 2V7QI 1YIJ2 3CC22 1KD13 3G6E2 1NJI3 2WSSI 1VQ62 2OTL2 1VQ42 1Q813 3OW21 1YIT2 1KQS1 2XNDI 3CPW1 3CCJ2 1Q863 1VQL2 1M903 1VQ52 1YJW2 1Q7Y3 3CCV2 3CCQ2 3CC42 1YHQ2 3G712 1Q823 4YXWI 3I552 3CXC1 1N8R3 1S722 1VQ92 1K9M3 2OTJ2 3CCE2 1E79I 1KC83 2XOKI 1YJ92 1K733 3G4S2 3CME2 1VQ82
chains in the Genus database with same CATH topology
1VQK2 3CCR2 1QVG1 1JJ21 3I562 1YJN2 2QEX2 3CC72 1VQM2 1YI22 1QVF1 1W2B1 3CD62 1VQO2 3CCU2 1K8A3 1VQN2 1VQP2 3CMA2 3CCM2 1VQ72 2QA42 3CCS2 3CCL2 1M1K3 1YIJ2 3CC22 1KD13 3G6E2 1NJI3 1VQ62 2OTL2 1VQ42 1Q813 3OW21 1YIT2 1KQS1 3CPW1 3CCJ2 1Q863 1VQL2 1M903 1VQ52 1YJW2 1Q7Y3 3CCV2 3CCQ2 3CC42 1YHQ2 3G712 1Q823 1K9M3 3I552 3CXC1 1N8R3 1S722 1VQ92 2OTJ2 3CCE2 1KC83 1YJ92 1K733 3G4S2 3CME2 1VQ82
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQK 2;  3CCR 2;  1QVG 1;  1JJ2 1;  3I56 2;  1YJN 2;  2QEX 2;  3CC7 2;  1VQM 2;  1YI2 2;  1QVF 1;  1W2B 1;  3CD6 2;  1VQO 2;  3CCU 2;  1K8A 3;  1VQN 2;  1VQP 2;  3CMA 2;  3CCM 2;  1VQ7 2;  2QA4 2;  3CCS 2;  3CCL 2;  1M1K 3;  1YIJ 2;  3CC2 2;  1KD1 3;  3G6E 2;  1NJI 3;  1VQ6 2;  2OTL 2;  1VQ4 2;  1Q81 3;  3OW2 1;  1YIT 2;  1KQS 1;  3CPW 1;  3CCJ 2;  1Q86 3;  1VQL 2;  1M90 3;  1VQ5 2;  1YJW 2;  1Q7Y 3;  3CCV 2;  3CCQ 2;  3CC4 2;  1YHQ 2;  3G71 2;  1Q82 3;  1K9M 3;  3I55 2;  3CXC 1;  1N8R 3;  1S72 2;  1VQ9 2;  2OTJ 2;  3CCE 2;  1KC8 3;  1YJ9 2;  1K73 3;  3G4S 2;  3CME 2;  1VQ8 2; 
#chains in the Genus database with same CATH topology
 1VQK 2;  3CCR 2;  1QVG 1;  1JJ2 1;  3I56 2;  1YJN 2;  2QEX 2;  3CC7 2;  1VQM 2;  1YI2 2;  1QVF 1;  1W2B 1;  3CD6 2;  3ZIA I;  1VQO 2;  3CCU 2;  3OFN I;  1K8A 3;  1VQN 2;  1VQP 2;  2WPD I;  3CMA 2;  3CCM 2;  1VQ7 2;  2QA4 2;  3CCS 2;  3CCL 2;  1M1K 3;  2V7Q I;  1YIJ 2;  3CC2 2;  1KD1 3;  3G6E 2;  1NJI 3;  2WSS I;  1VQ6 2;  2OTL 2;  1VQ4 2;  1Q81 3;  3OW2 1;  1YIT 2;  1KQS 1;  2XND I;  3CPW 1;  3CCJ 2;  1Q86 3;  1VQL 2;  1M90 3;  1VQ5 2;  1YJW 2;  1Q7Y 3;  3CCV 2;  3CCQ 2;  3CC4 2;  1YHQ 2;  3G71 2;  1Q82 3;  4YXW I;  3I55 2;  3CXC 1;  1N8R 3;  1S72 2;  1VQ9 2;  1K9M 3;  2OTJ 2;  3CCE 2;  1E79 I;  1KC8 3;  2XOK I;  1YJ9 2;  1K73 3;  3G4S 2;  3CME 2;  1VQ8 2; 
#chains in the Genus database with same CATH homology
 1VQK 2;  3CCR 2;  1QVG 1;  1JJ2 1;  3I56 2;  1YJN 2;  2QEX 2;  3CC7 2;  1VQM 2;  1YI2 2;  1QVF 1;  1W2B 1;  3CD6 2;  1VQO 2;  3CCU 2;  1K8A 3;  1VQN 2;  1VQP 2;  3CMA 2;  3CCM 2;  1VQ7 2;  2QA4 2;  3CCS 2;  3CCL 2;  1M1K 3;  1YIJ 2;  3CC2 2;  1KD1 3;  3G6E 2;  1NJI 3;  1VQ6 2;  2OTL 2;  1VQ4 2;  1Q81 3;  3OW2 1;  1YIT 2;  1KQS 1;  3CPW 1;  3CCJ 2;  1Q86 3;  1VQL 2;  1M90 3;  1VQ5 2;  1YJW 2;  1Q7Y 3;  3CCV 2;  3CCQ 2;  3CC4 2;  1YHQ 2;  3G71 2;  1Q82 3;  1K9M 3;  3I55 2;  3CXC 1;  1N8R 3;  1S72 2;  1VQ9 2;  2OTJ 2;  3CCE 2;  1KC8 3;  1YJ9 2;  1K73 3;  3G4S 2;  3CME 2;  1VQ8 2; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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