3CCQC

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488u
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 61
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 3ccqC00
1VQ9C 1K73E 3I56C 1Q86E 2OTJC 3CC4C 5DM7C 3CCVC 3CPWC 1VQPC 1QVFC 1VQ4C 1Q82E 1NJIE 1M1KE 1VQ5C 1VQ7C 2OTLC 3CD6C 2QEXC 1VQKC 3G71C 3CC7C 1YI2C 3G4SC 3CCEC 1VQMC 1S72C 1W2BC 2QA4C 1VQOC 1VQLC 1QVGC 3CMEC 1M90E 3CXCC 1YITC 3CCRC 3CCSC 3G6EC 1YHQC 1YJ9C 1Q7YE 1KC8E 1YJNC 1KQSC 3CCMC 3CCQC 1DMGA 1YIJC 4V19F 1K9ME 3CCJC 1YJWC 1K8AE 3I55C 1VQNC 1VQ6C 1N8RE 3CMAC 3J7YF 1KD1E 1JJ2C 1Q81E 1VQ8C 3CCUC 3CC2C 3CCLC 3OW2C
chains in the Genus database with same CATH superfamily
1VQ9C 1K73E 3I56C 1Q86E 2OTJC 3CC4C 5DM7C 3CCVC 3CPWC 1VQPC 1QVFC 1VQ4C 1Q82E 1NJIE 1M1KE 1VQ5C 1VQ7C 2OTLC 3CD6C 2QEXC 1VQKC 3G71C 3CC7C 1YI2C 3G4SC 3CCEC 1VQMC 1S72C 1W2BC 2QA4C 1VQOC 1VQLC 1QVGC 3CMEC 1M90E 3CXCC 1YITC 3CCRC 3CCSC 3G6EC 1YHQC 1YJ9C 1Q7YE 1KC8E 1YJNC 1KQSC 3CCMC 3CCQC 1DMGA 1YIJC 4V19F 1K9ME 3CCJC 1YJWC 1K8AE 3I55C 1VQNC 1VQ6C 1N8RE 3CMAC 3J7YF 1KD1E 1JJ2C 1Q81E 1VQ8C 3CCUC 3CC2C 3CCLC 3OW2C
chains in the Genus database with same CATH topology
1VQ9C 1K73E 3I56C 1Q86E 2OTJC 3CC4C 5DM7C 3CCVC 3CPWC 1VQPC 1QVFC 1VQ4C 1Q82E 1NJIE 1M1KE 1VQ5C 1VQ7C 2OTLC 3CD6C 2QEXC 1VQKC 3G71C 3CC7C 1YI2C 3G4SC 3CCEC 1VQMC 1S72C 1W2BC 2QA4C 1VQOC 1VQLC 1QVGC 3CMEC 1M90E 3CXCC 1YITC 3CCRC 3CCSC 3G6EC 1YHQC 1YJ9C 1Q7YE 1KC8E 1YJNC 1KQSC 3CCMC 3CCQC 1DMGA 1YIJC 4V19F 1K9ME 3CCJC 1YJWC 1K8AE 3I55C 1VQNC 1VQ6C 1N8RE 3CMAC 3J7YF 1KD1E 1JJ2C 1Q81E 1VQ8C 3CCUC 3CC2C 3CCLC 3OW2C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ9 C;  1K73 E;  3I56 C;  1Q86 E;  2OTJ C;  3CC4 C;  5DM7 C;  3CCV C;  3CPW C;  1VQP C;  1QVF C;  1VQ4 C;  1Q82 E;  1NJI E;  1M1K E;  1VQ5 C;  1VQ7 C;  2OTL C;  3CD6 C;  2QEX C;  1VQK C;  3G71 C;  3CC7 C;  1YI2 C;  3G4S C;  3CCE C;  1VQM C;  1S72 C;  1W2B C;  2QA4 C;  1VQO C;  1VQL C;  1QVG C;  3CME C;  1M90 E;  3CXC C;  1YIT C;  3CCR C;  3CCS C;  3G6E C;  1YHQ C;  1YJ9 C;  1Q7Y E;  1KC8 E;  1YJN C;  1KQS C;  3CCM C;  3CCQ C;  1DMG A;  1YIJ C;  4V19 F;  1K9M E;  3CCJ C;  1YJW C;  1K8A E;  3I55 C;  1VQN C;  1VQ6 C;  1N8R E;  3CMA C;  3J7Y F;  1KD1 E;  1JJ2 C;  1Q81 E;  1VQ8 C;  3CCU C;  3CC2 C;  3CCL C;  3OW2 C; 
#chains in the Genus database with same CATH topology
 1VQ9 C;  1K73 E;  3I56 C;  1Q86 E;  2OTJ C;  3CC4 C;  5DM7 C;  3CCV C;  3CPW C;  1VQP C;  1QVF C;  1VQ4 C;  1Q82 E;  1NJI E;  1M1K E;  1VQ5 C;  1VQ7 C;  2OTL C;  3CD6 C;  2QEX C;  1VQK C;  3G71 C;  3CC7 C;  1YI2 C;  3G4S C;  3CCE C;  1VQM C;  1S72 C;  1W2B C;  2QA4 C;  1VQO C;  1VQL C;  1QVG C;  3CME C;  1M90 E;  3CXC C;  1YIT C;  3CCR C;  3CCS C;  3G6E C;  1YHQ C;  1YJ9 C;  1Q7Y E;  1KC8 E;  1YJN C;  1KQS C;  3CCM C;  3CCQ C;  1DMG A;  1YIJ C;  4V19 F;  1K9M E;  3CCJ C;  1YJW C;  1K8A E;  3I55 C;  1VQN C;  1VQ6 C;  1N8R E;  3CMA C;  3J7Y F;  1KD1 E;  1JJ2 C;  1Q81 E;  1VQ8 C;  3CCU C;  3CC2 C;  3CCL C;  3OW2 C; 
#chains in the Genus database with same CATH homology
 1VQ9 C;  1K73 E;  3I56 C;  1Q86 E;  2OTJ C;  3CC4 C;  5DM7 C;  3CCV C;  3CPW C;  1VQP C;  1QVF C;  1VQ4 C;  1Q82 E;  1NJI E;  1M1K E;  1VQ5 C;  1VQ7 C;  2OTL C;  3CD6 C;  2QEX C;  1VQK C;  3G71 C;  3CC7 C;  1YI2 C;  3G4S C;  3CCE C;  1VQM C;  1S72 C;  1W2B C;  2QA4 C;  1VQO C;  1VQL C;  1QVG C;  3CME C;  1M90 E;  3CXC C;  1YIT C;  3CCR C;  3CCS C;  3G6E C;  1YHQ C;  1YJ9 C;  1Q7Y E;  1KC8 E;  1YJN C;  1KQS C;  3CCM C;  3CCQ C;  1DMG A;  1YIJ C;  4V19 F;  1K9M E;  3CCJ C;  1YJW C;  1K8A E;  3I55 C;  1VQN C;  1VQ6 C;  1N8R E;  3CMA C;  3J7Y F;  1KD1 E;  1JJ2 C;  1Q81 E;  1VQ8 C;  3CCU C;  3CC2 C;  3CCL C;  3OW2 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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