3CCVC

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 61
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 3ccvC00
3CCQC 1YIJC 1VQNC 1VQPC 1YJNC 1K9ME 3CMEC 1QVGC 3G4SC 1VQMC 3OW2C 1N8RE 2QEXC 1Q81E 3CC4C 3CCUC 3CPWC 1K8AE 1YJWC 1K73E 1KQSC 1VQ7C 4V19F 1Q86E 1YI2C 1VQ6C 3G6EC 1YHQC 1VQ5C 1VQKC 1VQ4C 3G71C 2QA4C 3CCMC 3CCRC 1W2BC 1NJIE 1YJ9C 3CCSC 1QVFC 3CCJC 1Q7YE 1M1KE 1VQ8C 3CCVC 2OTLC 3CD6C 1JJ2C 1S72C 1VQOC 1KC8E 3CCEC 1M90E 1VQ9C 5DM7C 3J7YF 3CCLC 1YITC 3I56C 3I55C 3CC2C 1DMGA 1VQLC 3CMAC 3CC7C 1KD1E 3CXCC 2OTJC 1Q82E
chains in the Genus database with same CATH superfamily
3CCQC 1YIJC 1VQNC 1VQPC 1YJNC 1K9ME 3CMEC 1QVGC 3G4SC 1VQMC 3OW2C 1N8RE 2QEXC 1Q81E 3CC4C 3CCUC 3CPWC 1K8AE 1YJWC 1K73E 1KQSC 1VQ7C 4V19F 1Q86E 1YI2C 1VQ6C 3G6EC 1YHQC 1VQ5C 1VQKC 1VQ4C 3G71C 2QA4C 3CCMC 3CCRC 1W2BC 1NJIE 1YJ9C 3CCSC 1QVFC 3CCJC 1Q7YE 1M1KE 1VQ8C 3CCVC 2OTLC 3CD6C 1JJ2C 1S72C 1VQOC 1KC8E 3CCEC 1M90E 1VQ9C 5DM7C 3J7YF 3CCLC 1YITC 3I56C 3I55C 3CC2C 1DMGA 1VQLC 3CMAC 3CC7C 1KD1E 3CXCC 2OTJC 1Q82E
chains in the Genus database with same CATH topology
3CCQC 1YIJC 1VQNC 1VQPC 1YJNC 1K9ME 3CMEC 1QVGC 3G4SC 1VQMC 3OW2C 1N8RE 2QEXC 1Q81E 3CC4C 3CCUC 3CPWC 1K8AE 1YJWC 1K73E 1KQSC 1VQ7C 4V19F 1Q86E 1YI2C 1VQ6C 3G6EC 1YHQC 1VQ5C 1VQKC 1VQ4C 3G71C 2QA4C 3CCMC 3CCRC 1W2BC 1NJIE 1YJ9C 3CCSC 1QVFC 3CCJC 1Q7YE 1M1KE 1VQ8C 3CCVC 2OTLC 3CD6C 1JJ2C 1S72C 1VQOC 1KC8E 3CCEC 1M90E 1VQ9C 5DM7C 3J7YF 3CCLC 1YITC 3I56C 3I55C 3CC2C 1DMGA 1VQLC 3CMAC 3CC7C 1KD1E 3CXCC 2OTJC 1Q82E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCQ C;  1YIJ C;  1VQN C;  1VQP C;  1YJN C;  1K9M E;  3CME C;  1QVG C;  3G4S C;  1VQM C;  3OW2 C;  1N8R E;  2QEX C;  1Q81 E;  3CC4 C;  3CCU C;  3CPW C;  1K8A E;  1YJW C;  1K73 E;  1KQS C;  1VQ7 C;  4V19 F;  1Q86 E;  1YI2 C;  1VQ6 C;  3G6E C;  1YHQ C;  1VQ5 C;  1VQK C;  1VQ4 C;  3G71 C;  2QA4 C;  3CCM C;  3CCR C;  1W2B C;  1NJI E;  1YJ9 C;  3CCS C;  1QVF C;  3CCJ C;  1Q7Y E;  1M1K E;  1VQ8 C;  3CCV C;  2OTL C;  3CD6 C;  1JJ2 C;  1S72 C;  1VQO C;  1KC8 E;  3CCE C;  1M90 E;  1VQ9 C;  5DM7 C;  3J7Y F;  3CCL C;  1YIT C;  3I56 C;  3I55 C;  3CC2 C;  1DMG A;  1VQL C;  3CMA C;  3CC7 C;  1KD1 E;  3CXC C;  2OTJ C;  1Q82 E; 
#chains in the Genus database with same CATH topology
 3CCQ C;  1YIJ C;  1VQN C;  1VQP C;  1YJN C;  1K9M E;  3CME C;  1QVG C;  3G4S C;  1VQM C;  3OW2 C;  1N8R E;  2QEX C;  1Q81 E;  3CC4 C;  3CCU C;  3CPW C;  1K8A E;  1YJW C;  1K73 E;  1KQS C;  1VQ7 C;  4V19 F;  1Q86 E;  1YI2 C;  1VQ6 C;  3G6E C;  1YHQ C;  1VQ5 C;  1VQK C;  1VQ4 C;  3G71 C;  2QA4 C;  3CCM C;  3CCR C;  1W2B C;  1NJI E;  1YJ9 C;  3CCS C;  1QVF C;  3CCJ C;  1Q7Y E;  1M1K E;  1VQ8 C;  3CCV C;  2OTL C;  3CD6 C;  1JJ2 C;  1S72 C;  1VQO C;  1KC8 E;  3CCE C;  1M90 E;  1VQ9 C;  5DM7 C;  3J7Y F;  3CCL C;  1YIT C;  3I56 C;  3I55 C;  3CC2 C;  1DMG A;  1VQL C;  3CMA C;  3CC7 C;  1KD1 E;  3CXC C;  2OTJ C;  1Q82 E; 
#chains in the Genus database with same CATH homology
 3CCQ C;  1YIJ C;  1VQN C;  1VQP C;  1YJN C;  1K9M E;  3CME C;  1QVG C;  3G4S C;  1VQM C;  3OW2 C;  1N8R E;  2QEX C;  1Q81 E;  3CC4 C;  3CCU C;  3CPW C;  1K8A E;  1YJW C;  1K73 E;  1KQS C;  1VQ7 C;  4V19 F;  1Q86 E;  1YI2 C;  1VQ6 C;  3G6E C;  1YHQ C;  1VQ5 C;  1VQK C;  1VQ4 C;  3G71 C;  2QA4 C;  3CCM C;  3CCR C;  1W2B C;  1NJI E;  1YJ9 C;  3CCS C;  1QVF C;  3CCJ C;  1Q7Y E;  1M1K E;  1VQ8 C;  3CCV C;  2OTL C;  3CD6 C;  1JJ2 C;  1S72 C;  1VQO C;  1KC8 E;  3CCE C;  1M90 E;  1VQ9 C;  5DM7 C;  3J7Y F;  3CCL C;  1YIT C;  3I56 C;  3I55 C;  3CC2 C;  1DMG A;  1VQL C;  3CMA C;  3CC7 C;  1KD1 E;  3CXC C;  2OTJ C;  1Q82 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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