3CXCL

The structure of an enhanced oxazolidinone inhibitor bound to the 50s ribosomal subunit of h. marismortui
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
194
structure length
194
Chain Sequence
ARSAYSYIREAWKRPKEGQIAELMWHRMQEWRNEPAVVRIERPTRLDRARSLGYKAKQGIIVVRVAIRKGSSRRTRFNKGRRSKRMMVNRITRKKNIQRIAEERANRKFPNLRVLNSYSVGEDGRHKWHEVILIDPDHPAIKSDDQLSWISRTRHRLRTFRGLTSAGRRCRGLRGQGKGSEKVRPSLRVNGAKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 52
structure length 194
sequence length 194
ec nomenclature
pdb deposition date 2008-04-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1120.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal protein L15e Ribosomal protein l15e 3cxcL00
2OTJM 3CC4M 3CCVM 1VQPM 1K73N 1VQ4M 1Q86N 3CXCL 1VQ5M 1VQ7M 2OTLM 1KQSL 3CD6M 2QEXM 1VQKM 3G71M 1YI2M 1S72M 3G4SM 1Q82N 1NJIN 1M1KN 1VQ8M 2QA4M 1VQOM 1VQLM 3CCEM 3CMEM 1KD1N 1YITM 3CCRM 3CCSM 3G6EM 1YHQM 1YJ9M 1YJNM 1M90N 3CCQM 3CCMM 1KC8N 1Q7YN 3CC7M 1YIJM 3CCJM 3OW2L 1YJWM 1JJ2L 3I55M 1K9MN 1VQNM 1VQ6M 1K8AN 3CPWL 3CMAM 1QVFL 1N8RN 3CC2M 1VQMM 3CCLM 3CCUM 1Q81N 1W2BL 1VQ9M 1QVGL 3I56M
chains in the Genus database with same CATH superfamily
2OTJM 3CC4M 3CCVM 1VQPM 1K73N 1VQ4M 1Q86N 3CXCL 1VQ5M 1VQ7M 2OTLM 1KQSL 3CD6M 2QEXM 1VQKM 3G71M 1YI2M 1S72M 3G4SM 1Q82N 1NJIN 1M1KN 1VQ8M 2QA4M 1VQOM 1VQLM 3CCEM 3CMEM 1KD1N 1YITM 3CCRM 3CCSM 3G6EM 1YHQM 1YJ9M 1YJNM 1M90N 3CCQM 3CCMM 1KC8N 1Q7YN 3CC7M 1YIJM 3CCJM 3OW2L 1YJWM 1JJ2L 3I55M 1K9MN 1VQNM 1VQ6M 1K8AN 3CPWL 3CMAM 1QVFL 1N8RN 3CC2M 1VQMM 3CCLM 3CCUM 1Q81N 1W2BL 1VQ9M 1QVGL 3I56M
chains in the Genus database with same CATH topology
2OTJM 3CC4M 3CCVM 1VQPM 1K73N 1VQ4M 1Q86N 3CXCL 1VQ5M 1VQ7M 2OTLM 1KQSL 3CD6M 2QEXM 1VQKM 3G71M 1YI2M 1S72M 3G4SM 1Q82N 1NJIN 1M1KN 1VQ8M 2QA4M 1VQOM 1VQLM 3CCEM 3CMEM 1KD1N 1YITM 3CCRM 3CCSM 3G6EM 1YHQM 1YJ9M 1YJNM 1M90N 3CCQM 3CCMM 1KC8N 1Q7YN 3CC7M 1YIJM 3CCJM 3OW2L 1YJWM 1JJ2L 3I55M 1K9MN 1VQNM 1VQ6M 1K8AN 3CPWL 3CMAM 1QVFL 1N8RN 3CC2M 1VQMM 3CCLM 3CCUM 1Q81N 1W2BL 1VQ9M 1QVGL 3I56M
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OTJ M;  3CC4 M;  3CCV M;  1VQP M;  1K73 N;  1VQ4 M;  1Q86 N;  3CXC L;  1VQ5 M;  1VQ7 M;  2OTL M;  1KQS L;  3CD6 M;  2QEX M;  1VQK M;  3G71 M;  1YI2 M;  1S72 M;  3G4S M;  1Q82 N;  1NJI N;  1M1K N;  1VQ8 M;  2QA4 M;  1VQO M;  1VQL M;  3CCE M;  3CME M;  1KD1 N;  1YIT M;  3CCR M;  3CCS M;  3G6E M;  1YHQ M;  1YJ9 M;  1YJN M;  1M90 N;  3CCQ M;  3CCM M;  1KC8 N;  1Q7Y N;  3CC7 M;  1YIJ M;  3CCJ M;  3OW2 L;  1YJW M;  1JJ2 L;  3I55 M;  1K9M N;  1VQN M;  1VQ6 M;  1K8A N;  3CPW L;  3CMA M;  1QVF L;  1N8R N;  3CC2 M;  1VQM M;  3CCL M;  3CCU M;  1Q81 N;  1W2B L;  1VQ9 M;  1QVG L;  3I56 M; 
#chains in the Genus database with same CATH topology
 2OTJ M;  3CC4 M;  3CCV M;  1VQP M;  1K73 N;  1VQ4 M;  1Q86 N;  3CXC L;  1VQ5 M;  1VQ7 M;  2OTL M;  1KQS L;  3CD6 M;  2QEX M;  1VQK M;  3G71 M;  1YI2 M;  1S72 M;  3G4S M;  1Q82 N;  1NJI N;  1M1K N;  1VQ8 M;  2QA4 M;  1VQO M;  1VQL M;  3CCE M;  3CME M;  1KD1 N;  1YIT M;  3CCR M;  3CCS M;  3G6E M;  1YHQ M;  1YJ9 M;  1YJN M;  1M90 N;  3CCQ M;  3CCM M;  1KC8 N;  1Q7Y N;  3CC7 M;  1YIJ M;  3CCJ M;  3OW2 L;  1YJW M;  1JJ2 L;  3I55 M;  1K9M N;  1VQN M;  1VQ6 M;  1K8A N;  3CPW L;  3CMA M;  1QVF L;  1N8R N;  3CC2 M;  1VQM M;  3CCL M;  3CCU M;  1Q81 N;  1W2B L;  1VQ9 M;  1QVG L;  3I56 M; 
#chains in the Genus database with same CATH homology
 2OTJ M;  3CC4 M;  3CCV M;  1VQP M;  1K73 N;  1VQ4 M;  1Q86 N;  3CXC L;  1VQ5 M;  1VQ7 M;  2OTL M;  1KQS L;  3CD6 M;  2QEX M;  1VQK M;  3G71 M;  1YI2 M;  1S72 M;  3G4S M;  1Q82 N;  1NJI N;  1M1K N;  1VQ8 M;  2QA4 M;  1VQO M;  1VQL M;  3CCE M;  3CME M;  1KD1 N;  1YIT M;  3CCR M;  3CCS M;  3G6E M;  1YHQ M;  1YJ9 M;  1YJN M;  1M90 N;  3CCQ M;  3CCM M;  1KC8 N;  1Q7Y N;  3CC7 M;  1YIJ M;  3CCJ M;  3OW2 L;  1YJW M;  1JJ2 L;  3I55 M;  1K9M N;  1VQN M;  1VQ6 M;  1K8A N;  3CPW L;  3CMA M;  1QVF L;  1N8R N;  3CC2 M;  1VQM M;  3CCL M;  3CCU M;  1Q81 N;  1W2B L;  1VQ9 M;  1QVG L;  3I56 M; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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