3DXKE

Structure of bos taurus arp2/3 complex with bound inhibitor ck0944636
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
174
structure length
174
Chain Sequence
PAYHSSLMDPDTKLIGNMALLPIRSQFKGPAPRETKDTDIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFPLNAIYAKPANKQEDEVMRAYLQQLRQETGLRLCEKVFDPQNDKPSKWWTCFVKRQFMNKSLSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterization of two classes of small molecule inhibitors of Arp2/3 complex
pubmed doi rcsb
molecule keywords Actin-related protein 3
molecule tags Structural protein
total genus 57
structure length 174
sequence length 174
ec nomenclature
pdb deposition date 2008-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF04062 P21-Arc ARP2/3 complex ARPC3 (21 kDa) subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1760.10 Mainly Alpha Orthogonal Bundle Arp2/3 complex 21 kDa subunit ARPC3 Actin-related protein 2/3 complex subunit 3 3dxkE00
4XEIE 1K8KE 2P9IE 1U2VE 4JD2E 3ULEE 3DXME 2P9LE 2P9KE 3RSEE 3UKRE 3UKUE 2P9SE 1TYQE 2P9PE 2P9NE 2P9UE 3DXKE
chains in the Genus database with same CATH superfamily
4TKRA 1K8KE 4M5BA 4HZUS 3DXKE 4HUQS 4DVEA 4N4DA 3ULEE 1U2VE 5KC0A 3UKRE 4POPA 5KC4A 5D0YA 2P9SE 4JD2E 2P9KE 2P9NE 2P9UE 4XEIE 4MESA 4MUUA 4Z7FA 5KBWA 3DXME 2P9LE 3RSEE 4MHWA 4M5CA 3UKUE 5JSZC 5D3MC 2P9PE 4POVA 2P9IE 4M58A 3RLBA 3P5NA 4RFSS 1TYQE
chains in the Genus database with same CATH topology
4XEIE 1K8KE 2P9IE 1U2VE 4JD2E 3ULEE 3DXME 2P9LE 2P9KE 3RSEE 3UKRE 3UKUE 2P9SE 1TYQE 2P9PE 2P9NE 2P9UE 3DXKE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XEI E;  1K8K E;  2P9I E;  1U2V E;  4JD2 E;  3ULE E;  3DXM E;  2P9L E;  2P9K E;  3RSE E;  3UKR E;  3UKU E;  2P9S E;  1TYQ E;  2P9P E;  2P9N E;  2P9U E;  3DXK E; 
#chains in the Genus database with same CATH topology
 4TKR A;  1K8K E;  4M5B A;  4HZU S;  3DXK E;  4HUQ S;  4DVE A;  4N4D A;  3ULE E;  1U2V E;  5KC0 A;  3UKR E;  4POP A;  5KC4 A;  5D0Y A;  2P9S E;  4JD2 E;  2P9K E;  2P9N E;  2P9U E;  4XEI E;  4MES A;  4MUU A;  4Z7F A;  5KBW A;  3DXM E;  2P9L E;  3RSE E;  4MHW A;  4M5C A;  3UKU E;  5JSZ C;  5D3M C;  2P9P E;  4POV A;  2P9I E;  4M58 A;  3RLB A;  3P5N A;  4RFS S;  1TYQ E; 
#chains in the Genus database with same CATH homology
 4XEI E;  1K8K E;  2P9I E;  1U2V E;  4JD2 E;  3ULE E;  3DXM E;  2P9L E;  2P9K E;  3RSE E;  3UKR E;  3UKU E;  2P9S E;  1TYQ E;  2P9P E;  2P9N E;  2P9U E;  3DXK E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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