3E2WA

H. influenzae beta-carbonic anhydrase, variant y181f with 1m bicarbonate
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
218
structure length
208
Chain Sequence
MDKIKQLFANNYSWAQRMKEENQTPHYLWIGCSDSRVPAEKLTNLEPGELFVHRNVANQVIHTDFNCLSVVQYAVDVLKIEHIIICGHTNCGGIHAAMADKDLGLINNWLLHIRDIWFKHGHLLGKLSPEKRADMLTKINVAEQVYNLGRTSIVKSAWERGQKLSLHGWVFDVNDGFLVDQGVMATSRETLEISYRNAIARLSILDEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Allosteric site variants of Haemophilus influenzae beta-carbonic anhydrase.
pubmed doi rcsb
molecule tags Lyase
source organism Haemophilus influenzae
molecule keywords Carbonic anhydrase 2
total genus 75
structure length 208
sequence length 218
chains with identical sequence B, C, D, E, F
ec nomenclature ec 4.2.1.1: Carbonic anhydrase.
pdb deposition date 2008-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00484 Pro_CA Carbonic anhydrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1050.10 Alpha Beta 3-Layer(aba) Sandwich Beta-carbonic Anhydrase; Chain A Carbonic anhydrase 3e2wA00
1I6PA 2A8CA 1DDZA 3E2XA 4YF5A 5BQ1A 4YF4A 5JJ8A 1T75A 2A8DA 4O1KA 3E31A 5CXKA 4ZNZA 3VQJA 4WAMA 3TEOA 3LASA 3VRKA 3UCNA 3E28A 3UCMA 4WAJA 4YF6A 2W3NA 3UCOA 3E2AA 4WAKA 2W3QA 5SWCA 3MF3A 1YM3A 4O1JA 3UCJA 3E3IA 3EYXA 3E1WA 1G5CA 3TENA 3E2WA 3E3GA 1EKJA 2ESFA 3E24A 2A5VA 3E3FA 3E1VA 3UCKA 1I6OA 4RXYA 1YLKA 3QY1A
chains in the Genus database with same CATH superfamily
1I6PA 2A8CA 1DDZA 3E2XA 4YF5A 5BQ1A 4YF4A 5JJ8A 1T75A 2A8DA 4O1KA 3E31A 5CXKA 4ZNZA 3VQJA 4WAMA 3TEOA 3LASA 3VRKA 3UCNA 3E28A 3UCMA 4WAJA 4YF6A 2W3NA 3UCOA 3E2AA 4WAKA 2W3QA 5SWCA 3MF3A 1YM3A 4O1JA 3UCJA 3E3IA 3EYXA 3E1WA 1G5CA 3TENA 3E2WA 3E3GA 1EKJA 2ESFA 3E24A 2A5VA 3E3FA 3E1VA 3UCKA 1I6OA 4RXYA 1YLKA 3QY1A
chains in the Genus database with same CATH topology
1I6PA 2A8CA 1DDZA 3E2XA 4YF5A 5BQ1A 4YF4A 5JJ8A 1T75A 2A8DA 4O1KA 3E31A 5CXKA 4ZNZA 3VQJA 4WAMA 3TEOA 3LASA 3VRKA 3UCNA 3E28A 3UCMA 4WAJA 4YF6A 2W3NA 3UCOA 3E2AA 4WAKA 2W3QA 5SWCA 3MF3A 1YM3A 4O1JA 3UCJA 3E3IA 3EYXA 3E1WA 1G5CA 3TENA 3E2WA 3E3GA 1EKJA 2ESFA 3E24A 2A5VA 3E3FA 3E1VA 3UCKA 1I6OA 4RXYA 1YLKA 3QY1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I6P A;  2A8C A;  1DDZ A;  3E2X A;  4YF5 A;  5BQ1 A;  4YF4 A;  5JJ8 A;  1T75 A;  2A8D A;  4O1K A;  3E31 A;  5CXK A;  4ZNZ A;  3VQJ A;  4WAM A;  3TEO A;  3LAS A;  3VRK A;  3UCN A;  3E28 A;  3UCM A;  4WAJ A;  4YF6 A;  2W3N A;  3UCO A;  3E2A A;  4WAK A;  2W3Q A;  5SWC A;  3MF3 A;  1YM3 A;  4O1J A;  3UCJ A;  3E3I A;  3EYX A;  3E1W A;  1G5C A;  3TEN A;  3E2W A;  3E3G A;  1EKJ A;  2ESF A;  3E24 A;  2A5V A;  3E3F A;  3E1V A;  3UCK A;  1I6O A;  4RXY A;  1YLK A;  3QY1 A; 
#chains in the Genus database with same CATH topology
 1I6P A;  2A8C A;  1DDZ A;  3E2X A;  4YF5 A;  5BQ1 A;  4YF4 A;  5JJ8 A;  1T75 A;  2A8D A;  4O1K A;  3E31 A;  5CXK A;  4ZNZ A;  3VQJ A;  4WAM A;  3TEO A;  3LAS A;  3VRK A;  3UCN A;  3E28 A;  3UCM A;  4WAJ A;  4YF6 A;  2W3N A;  3UCO A;  3E2A A;  4WAK A;  2W3Q A;  5SWC A;  3MF3 A;  1YM3 A;  4O1J A;  3UCJ A;  3E3I A;  3EYX A;  3E1W A;  1G5C A;  3TEN A;  3E2W A;  3E3G A;  1EKJ A;  2ESF A;  3E24 A;  2A5V A;  3E3F A;  3E1V A;  3UCK A;  1I6O A;  4RXY A;  1YLK A;  3QY1 A; 
#chains in the Genus database with same CATH homology
 1I6P A;  2A8C A;  1DDZ A;  3E2X A;  4YF5 A;  5BQ1 A;  4YF4 A;  5JJ8 A;  1T75 A;  2A8D A;  4O1K A;  3E31 A;  5CXK A;  4ZNZ A;  3VQJ A;  4WAM A;  3TEO A;  3LAS A;  3VRK A;  3UCN A;  3E28 A;  3UCM A;  4WAJ A;  4YF6 A;  2W3N A;  3UCO A;  3E2A A;  4WAK A;  2W3Q A;  5SWC A;  3MF3 A;  1YM3 A;  4O1J A;  3UCJ A;  3E3I A;  3EYX A;  3E1W A;  1G5C A;  3TEN A;  3E2W A;  3E3G A;  1EKJ A;  2ESF A;  3E24 A;  2A5V A;  3E3F A;  3E1V A;  3UCK A;  1I6O A;  4RXY A;  1YLK A;  3QY1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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