3G4SC

Co-crystal structure of tiamulin bound to the large ribosomal subunit
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 54
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2009-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 3g4sC00
3I55C 3CC4C 3CCMC 3CCRC 1VQOC 2QEXC 1K8AE 3CCLC 1YJWC 1KC8E 1Q7YE 1M1KE 1VQKC 3CXCC 3I56C 3CCEC 1VQ9C 2QA4C 1K9ME 3CPWC 1JJ2C 4V19F 1VQ5C 1W2BC 1K73E 3OW2C 1VQ4C 3CD6C 1VQPC 1QVGC 3CCSC 1YHQC 3G6EC 1KD1E 2OTLC 1YITC 1VQ6C 3CCJC 3CC7C 1DMGA 3G4SC 1NJIE 1VQNC 3CC2C 3CCVC 1N8RE 1VQ7C 1QVFC 1M90E 3G71C 1VQ8C 1YIJC 5DM7C 3CCQC 1VQLC 1YJ9C 3CMAC 1VQMC 3CMEC 3J7YF 1S72C 1YJNC 1Q82E 2OTJC 1Q86E 3CCUC 1KQSC 1YI2C 1Q81E
chains in the Genus database with same CATH superfamily
3I55C 3CC4C 3CCMC 3CCRC 1VQOC 2QEXC 1K8AE 3CCLC 1YJWC 1KC8E 1Q7YE 1M1KE 1VQKC 3CXCC 3I56C 3CCEC 1VQ9C 2QA4C 1K9ME 3CPWC 1JJ2C 4V19F 1VQ5C 1W2BC 1K73E 3OW2C 1VQ4C 3CD6C 1VQPC 1QVGC 3CCSC 1YHQC 3G6EC 1KD1E 2OTLC 1YITC 1VQ6C 3CCJC 3CC7C 1DMGA 3G4SC 1NJIE 1VQNC 3CC2C 3CCVC 1N8RE 1VQ7C 1QVFC 1M90E 3G71C 1VQ8C 1YIJC 5DM7C 3CCQC 1VQLC 1YJ9C 3CMAC 1VQMC 3CMEC 3J7YF 1S72C 1YJNC 1Q82E 2OTJC 1Q86E 3CCUC 1KQSC 1YI2C 1Q81E
chains in the Genus database with same CATH topology
3I55C 3CC4C 3CCMC 3CCRC 1VQOC 2QEXC 1K8AE 3CCLC 1YJWC 1KC8E 1Q7YE 1M1KE 1VQKC 3CXCC 3I56C 3CCEC 1VQ9C 2QA4C 1K9ME 3CPWC 1JJ2C 4V19F 1VQ5C 1W2BC 1K73E 3OW2C 1VQ4C 3CD6C 1VQPC 1QVGC 3CCSC 1YHQC 3G6EC 1KD1E 2OTLC 1YITC 1VQ6C 3CCJC 3CC7C 1DMGA 3G4SC 1NJIE 1VQNC 3CC2C 3CCVC 1N8RE 1VQ7C 1QVFC 1M90E 3G71C 1VQ8C 1YIJC 5DM7C 3CCQC 1VQLC 1YJ9C 3CMAC 1VQMC 3CMEC 3J7YF 1S72C 1YJNC 1Q82E 2OTJC 1Q86E 3CCUC 1KQSC 1YI2C 1Q81E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I55 C;  3CC4 C;  3CCM C;  3CCR C;  1VQO C;  2QEX C;  1K8A E;  3CCL C;  1YJW C;  1KC8 E;  1Q7Y E;  1M1K E;  1VQK C;  3CXC C;  3I56 C;  3CCE C;  1VQ9 C;  2QA4 C;  1K9M E;  3CPW C;  1JJ2 C;  4V19 F;  1VQ5 C;  1W2B C;  1K73 E;  3OW2 C;  1VQ4 C;  3CD6 C;  1VQP C;  1QVG C;  3CCS C;  1YHQ C;  3G6E C;  1KD1 E;  2OTL C;  1YIT C;  1VQ6 C;  3CCJ C;  3CC7 C;  1DMG A;  3G4S C;  1NJI E;  1VQN C;  3CC2 C;  3CCV C;  1N8R E;  1VQ7 C;  1QVF C;  1M90 E;  3G71 C;  1VQ8 C;  1YIJ C;  5DM7 C;  3CCQ C;  1VQL C;  1YJ9 C;  3CMA C;  1VQM C;  3CME C;  3J7Y F;  1S72 C;  1YJN C;  1Q82 E;  2OTJ C;  1Q86 E;  3CCU C;  1KQS C;  1YI2 C;  1Q81 E; 
#chains in the Genus database with same CATH topology
 3I55 C;  3CC4 C;  3CCM C;  3CCR C;  1VQO C;  2QEX C;  1K8A E;  3CCL C;  1YJW C;  1KC8 E;  1Q7Y E;  1M1K E;  1VQK C;  3CXC C;  3I56 C;  3CCE C;  1VQ9 C;  2QA4 C;  1K9M E;  3CPW C;  1JJ2 C;  4V19 F;  1VQ5 C;  1W2B C;  1K73 E;  3OW2 C;  1VQ4 C;  3CD6 C;  1VQP C;  1QVG C;  3CCS C;  1YHQ C;  3G6E C;  1KD1 E;  2OTL C;  1YIT C;  1VQ6 C;  3CCJ C;  3CC7 C;  1DMG A;  3G4S C;  1NJI E;  1VQN C;  3CC2 C;  3CCV C;  1N8R E;  1VQ7 C;  1QVF C;  1M90 E;  3G71 C;  1VQ8 C;  1YIJ C;  5DM7 C;  3CCQ C;  1VQL C;  1YJ9 C;  3CMA C;  1VQM C;  3CME C;  3J7Y F;  1S72 C;  1YJN C;  1Q82 E;  2OTJ C;  1Q86 E;  3CCU C;  1KQS C;  1YI2 C;  1Q81 E; 
#chains in the Genus database with same CATH homology
 3I55 C;  3CC4 C;  3CCM C;  3CCR C;  1VQO C;  2QEX C;  1K8A E;  3CCL C;  1YJW C;  1KC8 E;  1Q7Y E;  1M1K E;  1VQK C;  3CXC C;  3I56 C;  3CCE C;  1VQ9 C;  2QA4 C;  1K9M E;  3CPW C;  1JJ2 C;  4V19 F;  1VQ5 C;  1W2B C;  1K73 E;  3OW2 C;  1VQ4 C;  3CD6 C;  1VQP C;  1QVG C;  3CCS C;  1YHQ C;  3G6E C;  1KD1 E;  2OTL C;  1YIT C;  1VQ6 C;  3CCJ C;  3CC7 C;  1DMG A;  3G4S C;  1NJI E;  1VQN C;  3CC2 C;  3CCV C;  1N8R E;  1VQ7 C;  1QVF C;  1M90 E;  3G71 C;  1VQ8 C;  1YIJ C;  5DM7 C;  3CCQ C;  1VQL C;  1YJ9 C;  3CMA C;  1VQM C;  3CME C;  3J7Y F;  1S72 C;  1YJN C;  1Q82 E;  2OTJ C;  1Q86 E;  3CCU C;  1KQS C;  1YI2 C;  1Q81 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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